Description

Book Synopsis
Meeting the needs of patients while minimizing blood transfusions requires special expertise, precise monitoring and innovative techniques. This cutting-edge resource covers all the important clinical aspects of transfusion medicine in diverse clinical settings, with a special emphasis on alternatives to transfusion.

Edited by a multidisciplinary team consisting of a transfusion specialist, an anesthesiologist and an intensive care specialist this book is endorsed by the Network for Advancement of Transfusion Alternatives. The contributors review the appropriate use of fluids and of blood products, and describe the latest treatment options available to decrease the need for allogeneic blood products including:

  • Argon beam
  • Cell saver
  • Harmonic scalpel
  • Normovolemic haemodilution
  • Synthetic erythropoietin
  • Antifibrinolytics
  • Recombinant factor VIIa
  • Advanced monitoring of hemostasis
  • Intravenous iron


    • Trade Review
    "It would be of great interest to students or practitioners in laboratory and/or transfusion medicine, anesthesiology, and surgery interested in alternatives to blood transfusion. The editors and authors are credible authorities in their fields." (Doody's, 9 September 2011)

    "The book provides the state of the art in blood transfusion management and I shall certainly be referring to it often as I continue to develop a blood conservation programme in my own hospital." (The Bulletin of the Royal College of Pathologists, 1 July 2011)



    Table of Contents

    Contributors List ix

    Part 1 History and Development of Transfusion Medicine 1

    1 From Blood Transfusion to Transfusion Medicine 3
    Alice Maniatis

    Part 2 Allogeneic Blood Usage—Risks and Benefits 9

    2 Allogeneic Blood Components 11
    Rebecca Cardigan & Sheila MacLennan

    3 Current Information on the Infectious Risks of Allogeneic Blood Transfusion 21
    Alan D. Kitchen & John A. J. Barbara

    4 Immunological Complications of Blood Transfusion 31
    Clare Taylor Cristina Navarrete & Marcela Contreras

    5 Immunomodulation and Allogeneic Blood Transfusion 47
    Marloes Waanders Leo Van De Watering & Anneke Brand

    6 Pathogen Inactivation of Blood Components 60
    Chris Prowse

    7 The Benefits of Allogeneic Erythrocyte Transfusion: What Evidence Do We Have? 68
    Neil Soni & Benjamin Thomas

    Part 3 Volume Replacement 83

    Section 1 Plasma and Albumin 85

    8 Plasma and Albumin 87
    Philippe L. Baele

    Section 2 Crystalloids and Synthetic Colloids 109

    9 Pharmacology of Intravenous Fluids 111
    Michael F.M. James

    10 Crystalloids versus Colloids: The Controversy 119
    Hengo Haljamäe

    11 Effects of Synthetic Colloids on Hemostasis 137
    Sibylle A. Kozek-Langenecker & Gisela Scharbert

    12 Hydroxyethyl Starch and Renal Dysfunction 150
    Laurent Jacob Nicholas Heming & Bertrand Guidet

    13 Choice of a Synthetic Colloid for Surgery 158
    Joachim Boldt

    14 Choice of Colloid for Intensive Care Patients 168
    Yasser Sakr & Yalcin Inel

    15 Hypertonic Saline Solutions for the Initial Treatment of Patients with Traumatic Injuries 179
    Charles E. Wade & Michael A. Dubick

    16 Hyperchloremic Acidosis 194
    Edward Burdett & Andre Vercueil

    Part 4 Tolerance of Anemia 203

    17 Basic Principles of Oxygen Transport and Calculations 205
    Jean-Louis Vincent Pongdhep Theerawit & Davide Simion

    18 Assessment of Tissue Oxygenation 210
    Michael Piagnerelli Ann Dierick & Philippe Van der Linden

    19 Tissue Oxygenation and Blood Transfusion 218
    Stefan Suttner & Joachim Boldt

    20 Anemia and Cardiovascular Disease 229
    Antonis S. Manolis Spyridon Koulouris Kostas Triantafyllou Dimitris Sakellariou Sokratis Pastromas & Helen Melita

    Part 5 Perioperative Hemostasis 253

    21 Monitoring of Hemostasis in the Perioperative Setting 255
    Sibylle A. Kozek-Langenecker & Eva Schaden

    22 Antifibrinolytics in Open-Heart Surgery 267
    Wulf Dietrich

    23 Efficacy and Safety of Recombinant Activated Factor VII to Control Bleeding in Nonhemophiliac Patients 278
    Jean-François Hardy Sylvain Bélisle & Philippe Van der Linden

    Part 6 Transfusion Triggers 293

    24 Role of Hemoglobin/Hematocrit 295
    Kristine J. Guleserian Hae W. Kim Bruce Pearce Arkadiy Pitman & A. Gerson Greenburg

    25 Calculation of Blood Loss 303
    Mark E. Brecher

    26 Management of Massive Transfusion 313
    Jean-François Hardy & Marc Samama

    Part 7 Alternatives to Allogeneic Blood Transfusion 329 Section 1 Pharmaceutical Approaches 331

    27 Iron Deficiency: Causes Diagnosis and Management 335
    Manuel Muñoz José Antonio García-Erce & Elvira Bisbe

    28 Current Status of Perisurgical Erythropoietin Therapy 350
    Lawrence T. Goodnough

    29 Erythropoietin and Iron Therapy in Patients with Renal Failure 357
    Lucia Del Vecchio & Francesco Locatelli

    30 Hemoglobin-based Blood Substitutes 368
    G. Deby-Dupont Bernadette Remy & Maurice Lamy

    31 Perfluorocarbon Emulsions 380
    Pedro Cabrales

    Section 2 Surgical Techniques 389

    32 Minimally Invasive Cardiac Surgery: Impact on Blood Loss and Transfusion 391
    He Tao & Fraser Rubens

    33 Adjunctive Strategies to Impact Blood Transfusion in Cardiac Surgery 408
    L. Ressler & Fraser Rubens

    Section 3 Anesthetic Techniques 419

    34 Anesthetic Techniques to Reduce Blood Loss 421
    Dafydd Thomas

    35 Controlled Hypotension Decreases Blood Transfusion Requirement: Fact or Fallacy? 430
    Richard P. Dutton

    36 Acute Normovolemic Hemodilution 439
    Javad Bidgoli & Philippe Van der Linden

    37 Hyperoxic Hemodilution 450
    Jens Meier Konrad Messmer & Oliver Habler

    38 Intraoperative and Postoperative Cell Salvage 458
    Ernil Hansen & Hans Gombotz

    Section 4 Special Settings 475

    39 Anemia and Red Blood Transfusion in Critical Care 477
    Tim Walsh

    40 Red Blood Cell Transfusions and Alternatives to Treat the Anemia of Prematurity 490
    Ronald G. Strauss

    41 Transfusion Alternatives in Orthopedic Surgery 498
    Manuel Muñoz José Antonio García-Erce & Jorge Cuenca

    42 Transfusion Alternatives in Obstetrics 509
    Christian Breymann

    Part 8 Legal and Ethical Issues in Transfusion Medicine 521

    43 Ethical Aspects of Informed Consent: American Models 523
    Ronald E. Domen

    44 Blood Transfusions Jehovah’s Witnesses and the American Patients’ Rights Movement 531
    Charles H. Baron

    Part 9 Cost Issues 557

    45 The Cost and Cost-Effectiveness of Allogeneic and Autologous Blood 559
    Brian Custer

    46 Autologous Blood Predonation in Cardiac Surgery 569
    Wulf Dietrich

    47 Cost-Effectiveness of Pharmacological Alternatives 575
    Dean Fergusson & Brian Hutton

    Index 581

Alternatives to Blood Transfusion in Transfusion

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    A Hardback by Alice Maniatis, Jean-François Hardy, Phillipe van der Linden

      Trusted by thousands of customers. See 2,385+ Customer Reviews

      View other formats and editions of Alternatives to Blood Transfusion in Transfusion by Alice Maniatis

      Publisher: John Wiley and Sons Ltd
      Publication Date: 22/10/2010
      ISBN13: 9781405163217, 978-1405163217
      ISBN10: 1405163216
      Also in:
      Haematology

      Description

      Book Synopsis
      Meeting the needs of patients while minimizing blood transfusions requires special expertise, precise monitoring and innovative techniques. This cutting-edge resource covers all the important clinical aspects of transfusion medicine in diverse clinical settings, with a special emphasis on alternatives to transfusion.

      Edited by a multidisciplinary team consisting of a transfusion specialist, an anesthesiologist and an intensive care specialist this book is endorsed by the Network for Advancement of Transfusion Alternatives. The contributors review the appropriate use of fluids and of blood products, and describe the latest treatment options available to decrease the need for allogeneic blood products including:

      • Argon beam
      • Cell saver
      • Harmonic scalpel
      • Normovolemic haemodilution
      • Synthetic erythropoietin
      • Antifibrinolytics
      • Recombinant factor VIIa
      • Advanced monitoring of hemostasis
      • Intravenous iron


        • Trade Review
        "It would be of great interest to students or practitioners in laboratory and/or transfusion medicine, anesthesiology, and surgery interested in alternatives to blood transfusion. The editors and authors are credible authorities in their fields." (Doody's, 9 September 2011)

        "The book provides the state of the art in blood transfusion management and I shall certainly be referring to it often as I continue to develop a blood conservation programme in my own hospital." (The Bulletin of the Royal College of Pathologists, 1 July 2011)



        Table of Contents

        Contributors List ix

        Part 1 History and Development of Transfusion Medicine 1

        1 From Blood Transfusion to Transfusion Medicine 3
        Alice Maniatis

        Part 2 Allogeneic Blood Usage—Risks and Benefits 9

        2 Allogeneic Blood Components 11
        Rebecca Cardigan & Sheila MacLennan

        3 Current Information on the Infectious Risks of Allogeneic Blood Transfusion 21
        Alan D. Kitchen & John A. J. Barbara

        4 Immunological Complications of Blood Transfusion 31
        Clare Taylor Cristina Navarrete & Marcela Contreras

        5 Immunomodulation and Allogeneic Blood Transfusion 47
        Marloes Waanders Leo Van De Watering & Anneke Brand

        6 Pathogen Inactivation of Blood Components 60
        Chris Prowse

        7 The Benefits of Allogeneic Erythrocyte Transfusion: What Evidence Do We Have? 68
        Neil Soni & Benjamin Thomas

        Part 3 Volume Replacement 83

        Section 1 Plasma and Albumin 85

        8 Plasma and Albumin 87
        Philippe L. Baele

        Section 2 Crystalloids and Synthetic Colloids 109

        9 Pharmacology of Intravenous Fluids 111
        Michael F.M. James

        10 Crystalloids versus Colloids: The Controversy 119
        Hengo Haljamäe

        11 Effects of Synthetic Colloids on Hemostasis 137
        Sibylle A. Kozek-Langenecker & Gisela Scharbert

        12 Hydroxyethyl Starch and Renal Dysfunction 150
        Laurent Jacob Nicholas Heming & Bertrand Guidet

        13 Choice of a Synthetic Colloid for Surgery 158
        Joachim Boldt

        14 Choice of Colloid for Intensive Care Patients 168
        Yasser Sakr & Yalcin Inel

        15 Hypertonic Saline Solutions for the Initial Treatment of Patients with Traumatic Injuries 179
        Charles E. Wade & Michael A. Dubick

        16 Hyperchloremic Acidosis 194
        Edward Burdett & Andre Vercueil

        Part 4 Tolerance of Anemia 203

        17 Basic Principles of Oxygen Transport and Calculations 205
        Jean-Louis Vincent Pongdhep Theerawit & Davide Simion

        18 Assessment of Tissue Oxygenation 210
        Michael Piagnerelli Ann Dierick & Philippe Van der Linden

        19 Tissue Oxygenation and Blood Transfusion 218
        Stefan Suttner & Joachim Boldt

        20 Anemia and Cardiovascular Disease 229
        Antonis S. Manolis Spyridon Koulouris Kostas Triantafyllou Dimitris Sakellariou Sokratis Pastromas & Helen Melita

        Part 5 Perioperative Hemostasis 253

        21 Monitoring of Hemostasis in the Perioperative Setting 255
        Sibylle A. Kozek-Langenecker & Eva Schaden

        22 Antifibrinolytics in Open-Heart Surgery 267
        Wulf Dietrich

        23 Efficacy and Safety of Recombinant Activated Factor VII to Control Bleeding in Nonhemophiliac Patients 278
        Jean-François Hardy Sylvain Bélisle & Philippe Van der Linden

        Part 6 Transfusion Triggers 293

        24 Role of Hemoglobin/Hematocrit 295
        Kristine J. Guleserian Hae W. Kim Bruce Pearce Arkadiy Pitman & A. Gerson Greenburg

        25 Calculation of Blood Loss 303
        Mark E. Brecher

        26 Management of Massive Transfusion 313
        Jean-François Hardy & Marc Samama

        Part 7 Alternatives to Allogeneic Blood Transfusion 329 Section 1 Pharmaceutical Approaches 331

        27 Iron Deficiency: Causes Diagnosis and Management 335
        Manuel Muñoz José Antonio García-Erce & Elvira Bisbe

        28 Current Status of Perisurgical Erythropoietin Therapy 350
        Lawrence T. Goodnough

        29 Erythropoietin and Iron Therapy in Patients with Renal Failure 357
        Lucia Del Vecchio & Francesco Locatelli

        30 Hemoglobin-based Blood Substitutes 368
        G. Deby-Dupont Bernadette Remy & Maurice Lamy

        31 Perfluorocarbon Emulsions 380
        Pedro Cabrales

        Section 2 Surgical Techniques 389

        32 Minimally Invasive Cardiac Surgery: Impact on Blood Loss and Transfusion 391
        He Tao & Fraser Rubens

        33 Adjunctive Strategies to Impact Blood Transfusion in Cardiac Surgery 408
        L. Ressler & Fraser Rubens

        Section 3 Anesthetic Techniques 419

        34 Anesthetic Techniques to Reduce Blood Loss 421
        Dafydd Thomas

        35 Controlled Hypotension Decreases Blood Transfusion Requirement: Fact or Fallacy? 430
        Richard P. Dutton

        36 Acute Normovolemic Hemodilution 439
        Javad Bidgoli & Philippe Van der Linden

        37 Hyperoxic Hemodilution 450
        Jens Meier Konrad Messmer & Oliver Habler

        38 Intraoperative and Postoperative Cell Salvage 458
        Ernil Hansen & Hans Gombotz

        Section 4 Special Settings 475

        39 Anemia and Red Blood Transfusion in Critical Care 477
        Tim Walsh

        40 Red Blood Cell Transfusions and Alternatives to Treat the Anemia of Prematurity 490
        Ronald G. Strauss

        41 Transfusion Alternatives in Orthopedic Surgery 498
        Manuel Muñoz José Antonio García-Erce & Jorge Cuenca

        42 Transfusion Alternatives in Obstetrics 509
        Christian Breymann

        Part 8 Legal and Ethical Issues in Transfusion Medicine 521

        43 Ethical Aspects of Informed Consent: American Models 523
        Ronald E. Domen

        44 Blood Transfusions Jehovah’s Witnesses and the American Patients’ Rights Movement 531
        Charles H. Baron

        Part 9 Cost Issues 557

        45 The Cost and Cost-Effectiveness of Allogeneic and Autologous Blood 559
        Brian Custer

        46 Autologous Blood Predonation in Cardiac Surgery 569
        Wulf Dietrich

        47 Cost-Effectiveness of Pharmacological Alternatives 575
        Dean Fergusson & Brian Hutton

        Index 581

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