Education

The renowned translator Bhikkhu Bodhi has crafted this anthology of suttas from the Samyutta Nikaya to enable students of Early Buddhism to penetrate into the heart of the Buddha’s teachings on the four noble truths and the eightfold path as directly and clearly as possible. The aim is to attain direct insight into foundational Buddhist teachings on liberation.Brilliantly translated by Bhikkhu Bodhi, this anthology of suttas from the Samyutta Nikaya takes us straight to the heart of the Buddha’s teaching on liberation through the four noble truths and the noble eightfold path—the two mainstays of Buddhist doctrine that illuminate the nature of things and generate direct insight into the teachings. These suttas all pertain to the ultimate good, the attainment of nibbana, or liberation. They illuminate the Buddha’s radical diagnosis of the human condition—and more broadly, the condition of all sentient existence—in light of the four nobl

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Evidence-based insights into physical signs have evolved and progressed greatly over the past few years, further defining how physical findings identify disease, solve clinical problems, and forecast patient outcomes. Evidence-Based Physical Diagnosis, 5th Edition, is an up-to-date, authoritative resource for guidance on interpreting physical signs, enabling you to determine the most appropriate physical finding to confirm a diagnosis. Incorporating more than 200 new studies, this definitive text helps you glean the most from what you hear, see, and feel at the bedside-information that, combined with modern technologic testing, will grant clinicians the keys to outstanding patient care. Emphasizes the most important physical signs needed to determine the underlying condition or disease. Internationally renowned author Dr. Steven McGee shows readers how to pare down the multiple tests needed to confirm a diagnosis, saving both the physician and patient time and money. Features a reader-friendly outline format, including dozens of "EBM boxes" and accompanying "EBM ruler" illustrations. Contains thorough updates from cover to cover, including new evidence on the scientific value of the Romberg test (spinal stenosis); oximeter paradoxus (cardiac tamponade); platypnea (liver disease); pupil size in red eye (acute glaucoma); hum test (hearing loss); and many more. Begins each chapter with a list of Key Teaching Points, intended for readers desiring quick summaries and for teachers constructing concise bedside lessons. Features a unique evidence-based calculator online that enables you to easily determine probability using likelihood ratios. Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices.

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Master Your Minutes in Private and You’ll Master Your Life in PublicIn The Alone Advantage, Terri Savelle Foy shows how simple habits behind closed doors can reshape every aspect of your life.She knows what it’s like to be in a rut, repeating the same routine with no significant progress toward deep-down dreams. Terri started noticing that although the average person does not spend time alone—the average successful person does.Whatever your unique, God-given dream is, Terri reveals what successful people do in private to prepare and achieve the dreams in their heart. Discover: the morning routine that can change your life before breakfast, how to harness your imagination to visualize the future you want, and why successful people spend time alone.  Step-by-step, Terri shows you how realizing your biggest dream starts with a daily to-do list. As you learn the hab

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Who? Him. The Husband. Hero. Hunk.The Boy Next Door. The Paramour. The Je t'adore.Behind every famous man is a great woman – and from the quick-tongued Mrs Darwin to the lascivious Frau Freud, from the adoring Queen Kong to the long-suffering wife of the Devil himself, each one steps from her counterpart's shadow to tell her side of the story in this irresistible collection.Original, subversive, full of imagination and quicksilver wit, The World's Wife is Poet Laureate Carol Ann Duffy at her beguiling best.

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“Wade Davis is a true wayfinder, and these essays offer new insight into his visionary approach to culture, landscape, and the planet he loves as fiercely as any writer working today.”—John Vaillant, author of Fire WeatherA timely and eclectic collection from one of the foremost thinkers of our time, “a powerful, penetrating and immensely knowledgeable writer” (The Guardian).The essays in this collection came about during the unhurried months when one who had traveled incessantly was obliged to stay still, even as events flared on all sides in a world that never stops moving. Wade Davis brings his unique cultural perspective to such varied topics as the demonization of coca, the sacred plant of the Inca; the Great War and the birth of modernity; the British conquest of Everest; the endless conflict in the Middle East; reaching beyond climate fear and trepidation; on the meaning of the sacred. His essay, ̶

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This comprehensive book is an exploration of the history of veterinary medicine from the ancient world to the present as well as an examination of the development of man’s relationship with animals through early domestication, usage for food, fiber, traction, and transport to the current therapies and companion animals. The development of the discipline of veterinary medicine is explored through the transition from art to science and man’s deeper understanding of animals through research and investigation. It is now possible to read both the recorded 4000-year history of animal disease and veterinary development together with the story of the animal-human relationships and welfare as one cohesive text, with extensive backup. The book is organized so that it can be read in a linear manner, or for those researching a particular topic, by direct access to specific content. The species covered in detail are equine, bovine, ovine, caprine, porcine, canine, feline, avian, and aquatic, on every continent. The History of Veterinary Medicine and the Animal-Human Relationship is both an informative read and a definitive reference text for veterinary historians, veterinary history societies, veterinary librarians, and archivists.

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An incisive look into the early Buddhist teachings on emptiness, and a manual for bringing those teachings into our everyday lives.Before the growth of the Mahayana and the Perfection of Wisdom, the Buddha gave his own teachings, to his attendant Ananda, on the importance of emptiness (Pali sunnata, Sanskrit sunyata) in formal meditation and everyday practice. In this volume, renowned scholar-monk Bhikkhu Analayo explores these teachings and shows us how to integrate them into our lives. Bhikkhu Analayo draws from instructions found in the Greater and the Smaller Discourses on Emptiness (the Mahasunnatasutta and the Culasunnatasutta). In each chapter, he provides a translation of a pertinent excerpt from the discourses, follows this with clear and precise explanations of the text, and concludes by offering instructions for practice. Step by step, beginning with daily life and concluding with Nirvana, Bhikkhu Analayo unpacks t

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Every animal on earth has its own unique character—the slow sloth, the burrowing mole, the towering giraffe, the huge but flexible elephant. In nine vivid portrayals of different animals, Craig Holdrege shows how an animal's features are interconnected and reveal the animal as a whole. This insightful book presents readers with a fresh view of animals and nature by addressing each animal individually and succinctly asking, ‘who are you?’. This leads to a ground-breaking understanding of animal development and evolution as creative processes in which the animals are active participants. These revelations can help us find a way to learn from nature, rather than work against it, in order to improve the health of the planet in the future. An insightful and inspiring guide which encourages readers to change the way they think about animals, in order to understand how we can learn and grow from them.

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Authentic and practical teachings on what lies at the heart of Tibetan Buddhism, including karma, renunciation, bodhichitta, kindness, preparing for death, and much more.Perfect for practitioners, meditators, and anyone who wishes to better understand their own mind, this is an important message from a fresh voice within the tradition.Discover thoughtful advice and applicable practices for following a genuine Buddhist path and living a meaningful life in this succinct book. This profoundly graspable introduction to the heart of Tibetan Buddhism comes from a fresh voice within the tradition who has a growing online teaching presence. Khenpo Sherab Sangpo studied for decades with some of modern history''s greatest teachers in the Dzogchen lineage of Tibetan Buddhism, achieving impressive theoretical knowledge and experiential realization.This wide-ranging book offers easy-to-follow teachings and practices to cultivate a kind mind—bodhichitta&mdas

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Company Law Concentrate is written and designed to help you succeed. Accurate and reliable, Concentrate guides help consolidate your learning, focus your revision, and maximise your exam performance. Each guide includes revision tips, advice on how to achieve extra marks, and a thorough and focused breakdown of the key topics and cases. Key features: · Learn how to improve your performance in assessments - how to focus your revision, how to answer the question, and how to pick up extra marks · Written by experts and covering all the key topics so you can use alongside your textbook to consolidate notes and understanding, as well as approach your exams with confidence · Clear, concise, and easy-to-use, helping you get the most out of your revision · Full of learning features and tips to show you how best to impress your examiner · A wide array of accompanying online resources, including self-test questions, interactive key cases, and advice on revision and exam technique · Also available as an e-book with functionality and navigation features, as well as links that offer extra learning support Revision guides you can rely on: trusted by lecturers, loved by students... "The Concentrate books are my favourite revision guides as the quality of the information is always more comprehensive than others." Carly Hatchard, law student, University of Bolton "I am hugely impressed by this little textbook on the substance: it does a better and clearer job at explaining key issues than many of the core texts." Dr Eleni Frantziou, Associate Professor in Public Law & Human Rights, Durham University Digital Formats and Resources The 7th edition is available for students and institutions to purchase in a variety of formats, and is supported by extensive online resources to take your learning further. The e-book offers a mobile experience and convenient access along with functionality tools, navigation features, and links that offer extra learning support: www.oxfordtextbooks.co.uk/ebooks The online resources include: - advice on revision and exam technique from experienced examiner Nigel Foster; - a diagnostic test to help you pinpoint areas to focus your revision on; - interactive glossary and key cases to help you revise key terminology, facts, and principles; - multiple choice questions to test your knowledge; and - outline answers to questions in the book; - the author's accompanying Twitter feed (@UKCompanyLaw) to keep you updated.

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Two questions guide this seven-year project: First, how can we approach the phenomenon, representation, and interpretation of total solar eclipses? Second, how can we heal the historical divide separating the natural sciences from the humanities, arts, history, and theology? The result of this interdisciplinary investigation into eclipses is an exciting look behind the scenes - into labs, archives, and museums, as well as around fieldwork in astronomy, meteorology, animal behaviour, and ecophysiology. Carefully prepared for readers from all backgrounds, these voices invite us to imagine a liberated mode of discovery, perception, creativity, and knowledge-production across the traditional academic divisions. A uniquely prismatic representation of total solar eclipses emerges, itself rising to a model of communal thinking, together, across disciplinary borders. This book is Tom McLeish's final project and scholarly testament. Dedicated to him and to astrophysicist Jay M. Pasachoff (contributing author of a chapter about the solar corona, also Pasachoff's final piece of writing), the volume is a friendly companion to the chase of knowledge, encouraging its readers to embark upon their own interdisciplinary journey of discovery.

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Become proficient with the latest coding guidelines and codes with Bowie���s UNDERSTANDING ICD-10-CM AND ICD-10-PCS: A WORKTEXT, 2024 Edition. Updated each year, this hands-on worktext presents the most current diagnostic and procedural coding systems. Updates detail codes released in the 2024 revision with examples of new codes for various body systems. New ICD-10-PCS codes with explanations detailing specific directions for coding various procedures are also covered. An easy-to-follow approach incorporates professional exercises, expanded actual coding assignments and real case studies. Illustrations and links to medical research websites strengthen your knowledge of anatomy and disease processes to increase coding accuracy. MindTap online tools with Medical Coding Trainer and over 200 digital cases help prepare you for certification exams and diagnostic and procedural coding success.

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This Norton Critical Edition includes: Hans Walter Gabler’s acclaimed text of Joyce’s 1916 coming-of-age novel, accompanied by Gabler’s introduction and textual notes. Preface and revised and expanded explanatory annotations by John Paul Riquelme. Other writings by James Joyce closely related to A Portrait of the Artist as a Young Man, new to the Second Edition. Nine illustrations “Backgrounds and Contexts” including a wealth of materials, topically organised: “Political Nationalism: Irish History, 1798–1916”, “The Irish Literary and Cultural Revival”, “Religion” and “Aesthetic Backgrounds”. Twelve major critical assessments, seven of them new to the Second Edition. A chronology and a selected bibliography. About the Series Read by more than 12 million students over fifty-five years, Norton Critical Editions set the standard for apparatus that is right for undergraduate readers. The three-part format—annotated text, contexts and criticism—helps students to better understand, analyse and appreciate the literature, while opening a wide range of teaching possibilities for instructors. Whether in print or in digital format, Norton Critical Editions provide all the resources students need.

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‘Brilliant, eye-opening, and absolutely inspiring – and a riveting read.’ Cass Sunstein, author of How Change Happens and co-author of Nudge What is the secret to humanity’s evolutionary success? Could it be our strength, our intellect… or something much nicer? From the authors of New York Times bestseller The Genius of Dogs comes a powerful new idea about how ‘friendliness’ is the key factor in the flourishing of our species. Hare and Woods present an elegant new theory called self-domestication, looking at examples of co-operation and empathy and what this can tell us about the evolutionary success of Homo sapiens…

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'One can't help where one is born. Or one's station, of course. The trick to happiness is to be content where one is. Or so I am told.' 1979. Clarence House, London. The Queen Mother's receptions are in full swing and the champagne is flowing. Guiding the proceedings is William 'Billy' Tallon, page of the backstairs, keeper of the keys, holder of the royal corgis – and the royal secrets. Outside the palace walls, unemployment, inflation and industrial action are bringing Britain to its knees, and the country is on the verge of changing seismically under Prime Minister Margaret Thatcher. These two worlds are about to collide, with dizzying consequences for everyone... Backstairs Billy examines the fifty-year relationship between the Queen Mother and her most loyal, most outrageous servant, who joined her household at the age of fifteen. Marcelo Dos Santos's irreverent comedy was first produced by the Michael Grandage Company at the Duke of York's Theatre, London, in 2023, directed by Grandage and starring Penelope Wilton and Luke Evans.

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Withholding taxes have become a significant element of the system of international taxation in the wake of globalization and increased cross-border transactions. Deducting taxes at source has become a key tool for countries to ensure that individuals and entities do not escape their tax liabilities. This new work presents a comprehensive overview of the general mechanisms by which taxation is withheld in Europe and explores their practical implications.Florian Haase expertly navigates the complexities of international tax law and provides a rigorous examination of the challenges currently facing this area of legislation, including tax evasion and avoidance, double taxation, and tax treaties. Chapters cover key topics including the efforts towards harmonization and simplification, the impact of the digital economy, and the aim for tax transparency and base erosion prevention. Finally, the work covers the future of withholding taxes and the discussions and negotiations required to achieve consensus on common rules and practices.Key Features: Country-by-country analysis of relevant rules Comprehensive legislative and case law analysis Interaction between withholding taxes and EU law Thorough treatment of key substantive issues facing international tax law Detailed coverage of the technical and procedural aspects of withholding taxes This timely book will be an essential reference work for tax lawyers and practitioners and for scholars, researchers and students interested in tax law, European law and fiscal policy.

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Elgar Advanced Introductions are stimulating and thoughtful introductions to major fields in the social sciences, business and law, expertly written by the world’s leading scholars. Designed to be accessible yet rigorous, they offer concise and lucid surveys of the substantive and policy issues associated with discrete subject areas.This thoroughly updated second edition of Advanced Introduction to European Union Law provides an essential overview of the diverse fields of EU law and their relevant politics. In precise but accessible language, Jacques Ziller analyses the latest developments in EU law following Brexit, the Covid-19 pandemic, and the Russia-Ukraine war, focusing on the main fields of action for the EU: the internal market, area of freedom, security and justice, and external action.Key Features: Citations of critical legal texts to aid clarity for readers Insights on the EU’s founding treaties and how they have developed over time Analysis of the interactions and relations between the EU and its member states Discussion of both the legal and political aspects of the EU’s policies and institutions Providing an engaging entry point into the study of EU law, this Advanced Introduction will prove invaluable for students and academics in law, political science, and economics. It will also be an important resource for officials within the EU and its member states seeking a deeper understanding of the EU’s many laws and policies.

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#1 New York Times Best SellerThe national-bestselling, must-have science experiment series is back! MIT engineer Emily Calandrelli, host of Netflix’s Emily’s Wonder Lab and FOX’s Xploration Outer Space, is taking curiosity to the next level with 50 big, bold, brand-new experiments that sparkle, bubble, and explode. With this follow-up to the national bestseller Stay Curious and Keep Exploring, scientists of all ages will have a blast learning about STEAM concepts, playing, discovering spectacular Did You Know? facts, and being introduced to Who to Know, diverse biographies of rock stars in the science and technology world. Using easy-to-find items you'll learn to think like a scientist and conduct jaw-dropping experiments, including: Color-changing slimes to discover if dogs really do see the world in black and white A glow-in-t

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The radiography student’s ultimate guide to acing the ARRT® Certification ExamHailed by Doody’s Review Service as “the gold standard among instructors and students,” Radiography PREP delivers a concise summary of the entire radiography curriculum in a readable narrative. Written by an experienced program director, this is a true “must read” for certification or recertification. The book includes more than 900 ARRT-style review questions with detailed answer explanations for correct and incorrect answers, a practice exam, hundreds of illustrations and radiographic images, and powerful learning aids such as summary boxes and a glossary.This tenth edition features: Updated to reflect the most recent ARRT® Radiography Examination Accessible narrative style makes it easier to understand and remember key concepts Covers all the ARRT®content specifications More than 900 Q&A with detailed answer explanations Includes a comprehensive practice exam New: PowerPoint slide deck for instructors

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In Disaffected Xine Yao explores the racial and sexual politics of unfeeling—affects that are not recognized as feeling—as a means of survival and refusal in nineteenth-century America. She positions unfeeling beyond sentimentalism's paradigm of universal feeling. Yao traces how works by Herman Melville, Martin R. Delany, Elizabeth Stuart Phelps, Frances Ellen Watkins Harper, and Sui Sin Far engaged major sociopolitical issues in ways that resisted the weaponization of white sentimentalism against the lives of people of color. Exploring variously pathologized, racialized, queer, and gendered affective modes like unsympathetic Blackness, queer female frigidity, and Oriental inscrutability, these authors departed from the values that undergird the politics of recognition and the liberal project of inclusion. By theorizing feeling otherwise as an antisocial affect, form of dissent, and mode of care, Yao suggests that unfeeling can serve as a contemporary political strategy for people of color to survive in the face of continuing racism and white fragility. Duke University Press Scholars of Color First Book Award recipient

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Soaring Gothic cathedrals, violent crusades, the Black Death: these are the dramatic forces that shaped the medieval era. But the so-called Dark Ages also gave us the first universities, eyeglasses, and mechanical clocks. As medieval thinkers sought to understand the world around them, from the passing of the seasons to the stars in the sky, they came to develop a vibrant scientific culture. In The Light Ages, Cambridge science historian Seb Falk takes us on a tour of medieval science through the eyes of one fourteenth-century monk, John of Westwyk. Born in a rural manor, educated in England’s grandest monastery, and then exiled to a clifftop priory, Westwyk was an intrepid crusader, inventor, and astrologer. From multiplying Roman numerals to navigating by the stars, curing disease, and telling time with an ancient astrolabe, we learn emerging science alongside Westwyk and travel with him through the length and breadth of England and beyond its shores. On our way, we encounter a remarkable cast of characters: the clock-building English abbot with leprosy, the French craftsman-turned-spy, and the Persian polymath who founded the world’s most advanced observatory. The Light Ages offers a gripping story of the struggles and successes of an ordinary man in a precarious world and conjures a vivid picture of medieval life as we have never seen it before. An enlightening history that argues that these times weren’t so dark after all, The Light Ages shows how medieval ideas continue to color how we see the world today.

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If you know how to program, you're ready to tackle Bayesian statistics. With this book, you'll learn how to solve statistical problems with Python code instead of mathematical formulas, using discrete probability distributions rather than continuous mathematics. Once you get the math out of the way, the Bayesian fundamentals will become clearer and you'll begin to apply these techniques to real-world problems. Bayesian statistical methods are becoming more common and more important, but not many resources are available to help beginners. Based on undergraduate classes taught by author Allen B. Downey, this book's computational approach helps you get a solid start. Use your programming skills to learn and understand Bayesian statistics Work with problems involving estimation, prediction, decision analysis, evidence, and Bayesian hypothesis testing Get started with simple examples, using coins, dice, and a bowl of cookies Learn computational methods for solving real-world problems

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Anti-Money Laundering Regulation and Compliance: Key Problems and Practice Areas is a comprehensive treatment of the anti-money laundering/combatting the financing of terrorism (AML/CFT) and sanctions compliance programs, recordkeeping and reporting requirements, and the best practices under the Bank Secrecy Act (BSA) and sanctions regulatory regimes. AML/CFT and sanctions provisions are highly interrelated. Onboarding and customer due diligence requirements generate the data entered into transaction monitoring and screening systems.This book is unique in placing the prescriptive and program elements within the 'risk-based approach'that is foundational to AML/CFT compliance and the related risk management systems. Relatedly, the book describes corporate governance best practices and the 'three lines of defense' model that hold management accountable for exposure to money laundering and terrorist financing risks created by their business strategies. The book includes practical guidance on AML/CFT and sanctions model risk management, reflecting firms' growing reliance on machine learning and AI compliance solutions and the compliance risk of firms that adhere to Federal Reserve model risk management expectations. Also unique in the literature, it identifies a 'compliance paradox' that arises from the sharp tension between firms' modes of generating revenue and the law enforcement focus of AML/CFT and sanctions regulation and explains how this tension can compromise compliance.Anti-Money Laundering Regulation and Compliance also serves as a go-to guide for practitioners and beginners in the field or as a required text in graduate, certificate, and law school programs.

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The statistical analyses that students of the life-sciences are being expected to perform are becoming increasingly advanced. Whether at the undergraduate, graduate, or post-graduate level, this book provides the tools needed to properly analyze your data in an efficient, accessible, plainspoken, frank, and occasionally humorous manner, ensuring that readers come away with the knowledge of which analyses they should use and when they should use them. The book uses the statistical language R, which is the choice of ecologists worldwide and is rapidly becoming the 'go-to' stats program throughout the life-sciences. Furthermore, by using a single, real-world dataset throughout the book, readers are encouraged to become deeply familiar with an imperfect but realistic set of data. Indeed, early chapters are specifically designed to teach basic data manipulation skills and build good habits in preparation for learning more advanced analyses. This approach also demonstrates the importance of viewing data through different lenses, facilitating an easy and natural progression from linear and generalized linear models through to mixed effects versions of those same analyses. Readers will also learn advanced plotting and data-wrangling techniques, and gain an introduction to writing their own functions. Applied Statistics with R is suitable for senior undergraduate and graduate students, professional researchers, and practitioners throughout the life-sciences, whether in the fields of ecology, evolution, environmental studies, or computational biology.

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Impeccably researched and masterfully written, this book explains how and why humanity is driving itself off the cliff. — Dahr Jamail, author, The End of Ice Weaving together findings from a wide range of disciplines, Power traces how four key elements developed to give humans extraordinary power: tool making ability, language, social complexity, and the ability to harness energy sources ― most significantly, fossil fuels. It asks whether we have, at this point, overpowered natural and social systems, and if we have, what we can do about it. Has Homo sapiens — one species among millions — become powerful enough to threaten a mass extinction and disrupt the Earth's climate? Why have we developed so many ways of oppressing one another? Can we change our relationship with power to avert ecological catastrophe, reduce social inequality, and stave off collapse? These questions — and their answers — will determine our fate.

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The world can and will go on without us but I have to think that we have made this world a better place. That we have left it richer, wiser than had we not chosen the way of art. The 1996 Tony Award winner for Best Play. Terrence McNally's Master Class presents the legendary opera diva, Maria Callas, as she puts aspiring young singers through their paces in a series of master classes. Both moving and entertaining, this theatrical tour de force dramatizes the Callas phenomenon and "is an unembarrassed, involving meditation on Callas's life and the nature of her art. Such subjects are not easily dramatized, certainly not with this brio." (New York Times) After opening on Broadway in 1995 with Zoe Caldwell and Audra McDonald, the play premiered in London in 1997 with Patti LuPone. It was last revived on Broadway and in the West End in 2011-12 starring Tyne Daly.

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The twenty-first century has seen a breathtaking expansion of statistical methodology, both in scope and influence. 'Data science' and 'machine learning' have become familiar terms in the news, as statistical methods are brought to bear upon the enormous data sets of modern science and commerce. How did we get here? And where are we going? How does it all fit together? Now in paperback and fortified with exercises, this book delivers a concentrated course in modern statistical thinking. Beginning with classical inferential theories - Bayesian, frequentist, Fisherian - individual chapters take up a series of influential topics: survival analysis, logistic regression, empirical Bayes, the jackknife and bootstrap, random forests, neural networks, Markov Chain Monte Carlo, inference after model selection, and dozens more. The distinctly modern approach integrates methodology and algorithms with statistical inference. Each chapter ends with class-tested exercises, and the book concludes with speculation on the future direction of statistics and data science.

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This is an indispensable companion to the 'Sunflower book' - the highly acclaimed Illustrated Textbook of Paediatrics (6th Edition). It is essential for those who wish to test or improve their learning, or for exam revision for undergraduate or early postgraduate speciality exams. It includes high quality questions, some including images or diagrams, on important topics covering the paediatrics and child health curriculum. Explanations about both correct and incorrect answers are provided. The authors are highly experienced examiners and question writers, ensuring that the questions are similar to those encountered in exams or help explain difficult topics. Over 250 Single Best Answer questions Over 200 question stems for Extended Matching questions Explanations provided not only of the correct but also of incorrect answers Clinical photographs included to ask questions about clinical signs

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Written primarily for students embarking on an undergraduate bioscience degree, this primer introduces students to the essential topics in protein science clearly and concisely by describing the basic chemical structure of proteins, the factors that stabilize protein structures, protein function, and protein evolution. It begins by placing proteins in their general context in life. They are synthesized as amino-acid sequences encoded in genomes, and fold spontaneously to three-dimensional structures. This is the point where life makes the tremendous leap from the one-dimensional world of genome and amino-acid sequences, to the three-dimensional world of protein structures - indeed, the world which we inhabit. Protein Science prepares readers for later more advanced study of the subject, but will also leave readers who do not go on to such advanced study with a satisfying grasp of the essentials of the subject. Protein Science is supported by online resources and is available for students and institutions to purchase in a variety of formats. The e-book offers a mobile experience and convenient access along with functionality tools, navigation features and links that offer extra learning support: www.oxfordtextbooks.co.uk/ebooks The online resources include: For students: - Self-test questions - Animations of protein structures introduced in the text For registered adopters of the book: · Figures from the book, available to download

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Cybersecurity Risk Management In Cybersecurity Risk Management: Mastering the Fundamentals Using the NIST Cybersecurity Framework, veteran technology analyst Cynthia Brumfield, with contributions from cybersecurity expert Brian Haugli, delivers a straightforward and up-to-date exploration of the fundamentals of cybersecurity risk planning and management. The book offers readers easy-to-understand overviews of cybersecurity risk management principles, user, and network infrastructure planning, as well as the tools and techniques for detecting cyberattacks. The book also provides a roadmap to the development of a continuity of operations plan in the event of a cyberattack. With incisive insights into the Framework for Improving Cybersecurity of Critical Infrastructure produced by the United States National Institute of Standards and Technology (NIST), Cybersecurity Risk Management presents the gold standard in practical guidance for the implementation of risk management best practices. Filled with clear and easy-to-follow advice, this book also offers readers: A concise introduction to the principles of cybersecurity risk management and the steps necessary to manage digital risk to systems, assets, data, and capabilities A valuable exploration of modern tools that can improve an organization’s network infrastructure protection A practical discussion of the challenges involved in detecting and responding to a cyberattack and the importance of continuous security monitoring A helpful examination of the recovery from cybersecurity incidents Perfect for undergraduate and graduate students studying cybersecurity, Cybersecurity Risk Management is also an ideal resource for IT professionals working in private sector and government organizations worldwide who are considering implementing, or who may be required to implement, the NIST Framework at their organization.

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Endocrinology Enables readers to form an integrated understanding of endocrine physiology by examining the mechanisms of action of medical therapies Endocrinology: Pathophysiology to Therapy is a comprehensive resource on medical therapies; in each chapter, the relevant endocrine physiology of the medical therapy is presented, followed by a review of the detailed mechanism of action of selected medical interventions. Where applicable, emphasis is placed on clinical pharmacology pearls, such as side effects and therapeutic monitoring guidelines. Supplementary chapters address additional topics, including immune checkpoint inhibitor-related endocrinopathies, anabolic steroid abuse, pseudo-endocrine conditions, and dynamic tests in clinical endocrinology. Rather than emphasizing guideline-defined treatment protocols, this??book directs attention towards the pathophysiology and fundamental principles of endocrine therapies. Categories of therapies covered in Endocrinology include: Pituitary gland therapies, including Cushing’s disease, Acromegaly, Prolactinoma, adult growth hormone insufficiency, central diabetes insipidus, and syndrome of inappropriate ADH secretion Thyroid gland therapies, including Hashimoto’s thyroiditis, Graves’ Disease, Thyroid Eye Disease, Riedel’s thyroiditis, Thyroid hormone resistance, and RSH secreting tumors Adrenal gland therapies, including primary adrenal insufficiency, primary hyperaldosteronism, classic congenital adrenal hyperplasia, and nonclassic congenital adrenal hyperplasia Pancreatic gland therapies, including diabetes mellitus, neuroendocrine tumors, and hypoglycemia syndromes such as somatostatin analogs and calcium channel blockers Discussing the rationale for using various therapies and enabling readers to appreciate complex concepts in a clinically relevant manner, Endocrinology is an essential reference for practitioners in related fields looking for an accessible and comprehensive resource on the subject.

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Thomas Nail approaches the theory of objects historically in order to tell a completely new story in which objects themselves are the true agents of scientific knowledge. They are processes, not things. This is the first history of science and technology, from prehistory to the present, illuminating the agency, knowledge and mobility of objects.

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Groundwater Science, Third Edition covers physical and chemical aspects of groundwater science, with emphasis on applications in the hydrologic cycle and in water supply, including contamination, mining, and construction issues. This interdisciplinary text weaves important methods and applications from the disciplines of physics, chemistry, mathematics, geology, biology, and environmental science, introducing the mathematical modeling of groundwater flow and contaminant transport. This fully updated edition includes all new case studies, expanded ancillary materials (including software), and expanded problems. The book is a valuable resource for students and instructors in the geosciences, environmental sciences, and civil engineering with a focus on hydrology and hydrogeology.

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Arriving from his East Midlands beginnings into a London thick with the grime of industrialisation, Joseph Merrick is an anomaly. In a city of factories that churn out uniformity, there is no place for someone like him. But Merrick and the city are evolving into something new. We follow him through the workhouse, the freak show and the hospital, as he searches for acceptance in a society that just wants to stare at him. Powerful, angry and surprising, Tom Wright's acclaimed play imagines an alternative history of the person who came to be known as 'the Elephant Man'. It restores Joseph Merrick to the centre of his own story: a man fighting for his right to be and to belong. The Real & Imagined History of the Elephant Man was first performed at Melbourne's Malthouse Theatre, before receiving its European premiere at Nottingham Playhouse in 2023, directed by Stephen Bailey, and supported by a grant from The Royal Theatrical Support Trust.

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