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Book Synopsis
Vincristine is a naturally occurring alkaloid isolated from the leaves of the plant Catharanthus roseus. It has a wide range of clinical applications. Extracts of the plant have found application in wound healing, in the treatment of diabetic ulcers and diabetes mellitus, and in cancer chemotherapy. In this book, the authors discuss the clinical uses, pharmacokinetics and impacts on health of Vincristine. Topics discussed include Vincristine as an inductor of drug resistance marker expression in neoplastic cells; clinical utility of Vincristine in the treatment of human carcinomas; inadvertent intrathecal administration of Vincristine; and Vincristine''s mechanism of anti-tumor activity.

Vincristine: Clinical Uses, Pharmacokinetics &

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    A Hardback by Juan M Coello, Yolanda D Sabres

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      Publisher: Nova Science Publishers Inc
      Publication Date: 25/10/2013
      ISBN13: 9781628088861, 978-1628088861
      ISBN10: 1628088869
      Also in:
      Pharmacology

      Description

      Book Synopsis
      Vincristine is a naturally occurring alkaloid isolated from the leaves of the plant Catharanthus roseus. It has a wide range of clinical applications. Extracts of the plant have found application in wound healing, in the treatment of diabetic ulcers and diabetes mellitus, and in cancer chemotherapy. In this book, the authors discuss the clinical uses, pharmacokinetics and impacts on health of Vincristine. Topics discussed include Vincristine as an inductor of drug resistance marker expression in neoplastic cells; clinical utility of Vincristine in the treatment of human carcinomas; inadvertent intrathecal administration of Vincristine; and Vincristine''s mechanism of anti-tumor activity.

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