Description

Book Synopsis
The leading guide to the principles and clinical applications of evidence-based medicineâupdated with new examples and new chapters

A Doody's Core Title for 2022 & 2024!


  • Revised and updated to reflect the latest in medical research and evidence-based resources
  • Practical focus and organization to guide clinicians through the fundamentals of using the medical literature to the more advanced strategies and skills for use in patient care, using the key questions to assess any new research:
    • What are the results?
    • How serious is the risk of bias?
    • How do I apply the results to patient care?
  • Updated real-world examples drawn from the medical literature
  • New chapters that reflect the changing complexity of medical research and literature, including genetic association studies, systematic reviews and meta-analyses, network meta-analysis, noninferiority trials, quality improvement, and evidence-based med

    Table of Contents
    Foreword
    Preface
    The Foundations
    1 How to Use the Medical Literature—and This Book—to Improve Your Patient Care
    2 What Is Evidence-Based Medicine?
    3 Evidence-Based Medicine and the Theory of Knowledge
    4 What Is the Question?
    5 Finding Current Best Evidence
    6 Why Study Results Mislead: Bias and Random Error
    Therapy
    7 Therapy (Randomized Trials)
    8 How to Use a Noninferiority Trial
    9 Does Treatment Lower Risk? Understanding the Results
    10 Confidence Intervals: Was the Single Study or Meta-analysis Large Enough?
    11 Advanced Topics in the Risk of Bias of Therapy Trials
    11.1 An Illustration of Bias and Random Error
    11.2 Surprising Results of Randomized Trials
    11.3 Randomized Trials Stopped Early for Benefit
    11.4 The Principle of Intention to Treat and Ambiguous Dropouts
    11.5 N-of-1 Randomized Clinical Trials
    11.6 Clinical Decision Support Systems
    11.7 How to Use an Article About Quality Improvement
    12 Advanced Topics in the Results of Therapy Trials
    12.1 Hypothesis Testing
    12.2 Understanding the Results: More About Odds Ratios
    12.3 What Determines the Width of the Confidence Interval?
    12.4 Composite End Points
    12.5 Measuring Patients’ Experience
    13 Advanced Topics in Applying the Results of Therapy Trials
    13.1 Applying Results to Individual Patients
    13.2 Numbers Needed to Treat
    13.3 Misleading Presentations of Clinical Trial Results
    13.4 Surrogate Outcomes
    13.5 Qualitative Research
    Harm (Observational Studies)
    14 Harm (Observational Studies)
    15 Advanced Topics in Harm
    15.1 Correlation and Regression
    Diagnosis
    16 The Process of Diagnosis
    17 Differential Diagnosis
    18 Diagnostic Tests
    19 Advanced Topics in Diagnosis
    19.1 Spectrum Bias
    19.2 Examples of Likelihood Ratios
    19.3 Measuring Agreement Beyond Chance
    19.4 Clinical Prediction Rules
    Prognosis
    20 Prognosis
    21 Advanced Topics in Prognosis
    21.1 How to Use an Article About Genetic Association
    Summarizing the Evidence
    22 The Process of a Systematic Review and Meta-analysis
    23 Understanding and Applying the Results of a Systematic Review and Meta-analysis
    24 Network Meta-analysis
    25 Advanced Topics in Systematic Reviews
    25.1 Fixed-Effects and Random-Effects Models
    25.2 How to Use a Subgroup Analysis
    Moving From Evidence to Action
    26 How to Use a Patient Management Recommendation: Clinical Practice Guidelines and Decision Analyses
    27 Decision Making and the Patient
    28 Advanced Topics in Moving From Evidence to Action
    28.1 Assessing the Strength of Recommendations: The GRADE Approach
    28.2 Economic Analysis
    28.3 Recommendations About Screening
    28.4 Understanding Class Effects
    28.5 Evidence-Based Practitioners and Evidence-Based Care
    29 Teachers’ Guides to the Users’ Guides
    Glossary
    Index

Users Guides to the Medical Literature A Manual

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    £74.09

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    Order before 4pm today for delivery by Tue 7 Jul 2026.

    A Paperback / softback by Gordon Guyatt

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      Publisher: McGraw-Hill Education - Europe
      Publication Date: 16/02/2015
      ISBN13: 9780071790710, 978-0071790710
      ISBN10: 0071790713
      Also in:
      Medicine / Healthcare: general issues / topics

      Description

      Book Synopsis
      The leading guide to the principles and clinical applications of evidence-based medicineâupdated with new examples and new chapters

      A Doody's Core Title for 2022 & 2024!


      • Revised and updated to reflect the latest in medical research and evidence-based resources
      • Practical focus and organization to guide clinicians through the fundamentals of using the medical literature to the more advanced strategies and skills for use in patient care, using the key questions to assess any new research:
        • What are the results?
        • How serious is the risk of bias?
        • How do I apply the results to patient care?
      • Updated real-world examples drawn from the medical literature
      • New chapters that reflect the changing complexity of medical research and literature, including genetic association studies, systematic reviews and meta-analyses, network meta-analysis, noninferiority trials, quality improvement, and evidence-based med

        Table of Contents
        Foreword
        Preface
        The Foundations
        1 How to Use the Medical Literature—and This Book—to Improve Your Patient Care
        2 What Is Evidence-Based Medicine?
        3 Evidence-Based Medicine and the Theory of Knowledge
        4 What Is the Question?
        5 Finding Current Best Evidence
        6 Why Study Results Mislead: Bias and Random Error
        Therapy
        7 Therapy (Randomized Trials)
        8 How to Use a Noninferiority Trial
        9 Does Treatment Lower Risk? Understanding the Results
        10 Confidence Intervals: Was the Single Study or Meta-analysis Large Enough?
        11 Advanced Topics in the Risk of Bias of Therapy Trials
        11.1 An Illustration of Bias and Random Error
        11.2 Surprising Results of Randomized Trials
        11.3 Randomized Trials Stopped Early for Benefit
        11.4 The Principle of Intention to Treat and Ambiguous Dropouts
        11.5 N-of-1 Randomized Clinical Trials
        11.6 Clinical Decision Support Systems
        11.7 How to Use an Article About Quality Improvement
        12 Advanced Topics in the Results of Therapy Trials
        12.1 Hypothesis Testing
        12.2 Understanding the Results: More About Odds Ratios
        12.3 What Determines the Width of the Confidence Interval?
        12.4 Composite End Points
        12.5 Measuring Patients’ Experience
        13 Advanced Topics in Applying the Results of Therapy Trials
        13.1 Applying Results to Individual Patients
        13.2 Numbers Needed to Treat
        13.3 Misleading Presentations of Clinical Trial Results
        13.4 Surrogate Outcomes
        13.5 Qualitative Research
        Harm (Observational Studies)
        14 Harm (Observational Studies)
        15 Advanced Topics in Harm
        15.1 Correlation and Regression
        Diagnosis
        16 The Process of Diagnosis
        17 Differential Diagnosis
        18 Diagnostic Tests
        19 Advanced Topics in Diagnosis
        19.1 Spectrum Bias
        19.2 Examples of Likelihood Ratios
        19.3 Measuring Agreement Beyond Chance
        19.4 Clinical Prediction Rules
        Prognosis
        20 Prognosis
        21 Advanced Topics in Prognosis
        21.1 How to Use an Article About Genetic Association
        Summarizing the Evidence
        22 The Process of a Systematic Review and Meta-analysis
        23 Understanding and Applying the Results of a Systematic Review and Meta-analysis
        24 Network Meta-analysis
        25 Advanced Topics in Systematic Reviews
        25.1 Fixed-Effects and Random-Effects Models
        25.2 How to Use a Subgroup Analysis
        Moving From Evidence to Action
        26 How to Use a Patient Management Recommendation: Clinical Practice Guidelines and Decision Analyses
        27 Decision Making and the Patient
        28 Advanced Topics in Moving From Evidence to Action
        28.1 Assessing the Strength of Recommendations: The GRADE Approach
        28.2 Economic Analysis
        28.3 Recommendations About Screening
        28.4 Understanding Class Effects
        28.5 Evidence-Based Practitioners and Evidence-Based Care
        29 Teachers’ Guides to the Users’ Guides
        Glossary
        Index

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