Description

Book Synopsis

This brief is a concise guide that explores the theory and practical aspects of improving enantioselectivity in enzymatic kinetic resolution, with a specific focus on the role of hydrolases in this process. Enzymatic kinetic resolution is a valuable technique for obtaining enantiopure compounds, and hydrolases are highlighted as a crucial class of enzymes widely used in industries for chiral synthesis involving kinetic resolution. The book emphasizes the importance of tuning and optimizing the enzymatic kinetic resolution process to achieve the highest possible enantiomeric excess in the final product or starting material while maintaining the desired yield. Through illustrative examples, the text aims to make the concept accessible and appealing to graduate students, researchers, and young organic chemists seeking to incorporate hydrolases in their stereoselective synthesis endeavors.



Table of Contents

Understanding Enzymatic Kinetic Resolution.- Essential Parameters: Determination and Significance - Enantioselectivity: The Decisive Factors.- Dynamic Kinetic Resolution.

Understanding Kinetic Resolution by Hydrolases: Maximizing Enantioselectivity

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    A Paperback by Abir B. Majumder, Kalluri V. S. Ranganath

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      Book details

      Publisher Springer International Publishing AG
      Published 2 January 2024
      ISBN-13 9783031463525
      978-3031463525
      ISBN-10 3031463528
      Also in:
      Science & Nature Biochemistry Catalysis Organic chemistry

      Description

      Book Synopsis

      This brief is a concise guide that explores the theory and practical aspects of improving enantioselectivity in enzymatic kinetic resolution, with a specific focus on the role of hydrolases in this process. Enzymatic kinetic resolution is a valuable technique for obtaining enantiopure compounds, and hydrolases are highlighted as a crucial class of enzymes widely used in industries for chiral synthesis involving kinetic resolution. The book emphasizes the importance of tuning and optimizing the enzymatic kinetic resolution process to achieve the highest possible enantiomeric excess in the final product or starting material while maintaining the desired yield. Through illustrative examples, the text aims to make the concept accessible and appealing to graduate students, researchers, and young organic chemists seeking to incorporate hydrolases in their stereoselective synthesis endeavors.



      Table of Contents

      Understanding Enzymatic Kinetic Resolution.- Essential Parameters: Determination and Significance - Enantioselectivity: The Decisive Factors.- Dynamic Kinetic Resolution.

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