Description
Book SynopsisThis is a comprehensive and authoritative presentation of total intravenous anesthesia (TIVA) and target controlled infusion (TCI). The editors’ international reputation has enabled them to recruit leading experts from around the world to write single-author chapters in their area of expertise.
Total Intravenous Anesthesia and Target Controlled Infusions is the first multi-disciplinary, globally authored volume on the topic.
Providing a single source of information on all aspects of TIVA and TCI, from pharmacologic modeling and the pharmacology of intravenous anesthetic drugs to practical considerations in the clinical setting and the requirements of special populations,
Total Intravenous Anesthesia and Target Controlled Infusions examines the debate about the risks and advantages of TIVA, analyze outcome studies, and provides guidance on creating a curriculum to teach TIVA and TCI.
Trade Review“Total Intravenous Anesthesia and Target Controlled Infusions is a traditional textbook that bills itself as a comprehensive guide to the subject. … this textbook form part of the reference collection of all anesthetic department libraries. It is a high-quality volume, well bound with excellent color illustrations, printed on thick paper, and is a worthwhile purchase. … Those that take the time to read a good portion of it will be richly rewarded in their increased understanding of TIVA.” (Timothy G. Short and Gerard Willemsen, Anestesia & Analgesia, Vol. 125 (1), January, 2018)
Table of ContentsCONTENTS
PART 1. INTRODUCTION/BACKGROUND
1. When and How Did It All Begin? A Brief History of Intravenous Anesthesia
John Sear
2. The Development and Regulation of Commercial Devices for Target - Controlled Drug Infusion
John B Glen
3. The Memory Labyrinth: systems, processes and boundaries
Robert A. Veselis
4. Consciousness and Anaesthesia
Ram Adapa
5. Mechanisms of Intravenous Anaesthetic Action
Hugh C. Hemmings Jr and Karl F. Herold
PART 2. PRINCIPLES OF PHARMACOLOGICAL MODELING
6. Basic Pharmacology: Kinetics and Dynamics for Dummies
Johan Raeder
7. Pharmacokinetic-Pharmacodynamic Modelling of Anesthetic Drugs
Johannes Hans Proost
8. Principles of Target Controlled Infusions
Steven L. Shafer
9. Performance of Target-Controlled Infusion Systems
Matthew TV Chan
10. How to Select a PK/PD Model
Kenichi Masui
PART 3. PHARMACOLOGY OF THE INTRAVENOUS ANESTHETIC AGENTS
11. Propofol PK-PD
Douglas J. Eleveld
12. Etomidate and Etomidate Analogues: Molecular Pharmacology and Behavioral Actions
Douglas E. Raines
13. Dexmedetomidine: The Science and Clinical Aspects in Adults and Children
Mohamed Mahmoud
14. Clinical Effects and Applications of Ketamine
Mark G. Roback
15. Neuromuscular Blocking Drugs: Pharmacology, Physiology and Clinical Aspects
Claude Meistelman
16. New and Upcoming Drugs: Intravenous Anesthetic Agents
John William Sear
17. Drug Interactions in Anesthesia
Jaap Vuyk
PART 4. PRACTICAL CONDUCT OF SEDATION AND ANESTHESIA
18. Pumps Pitfalls and Practicalities
Frank Engbers
19. EEG Monitoring of Depth of Anesthesia
Michael Sury
20. Monitoring the analgesic component of anesthesia
Isabelle Constant<
21. Intravenous Drugs for Sedation: Target Controlled, Patient Controlled, and Patient Maintained Delivery
Keith J Anderson and Gavin NC Kenny
22. Pediatric TIVA/TCI: Case Presentations and Discussion
Vivian Man-ying Yuen
23. TCI/TIVA Adult Case Studies
Nicholas Sutcliffe
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PART 5. SPECIAL POPULATIONS AND PROCEDURES
24. Intravenous Anesthesia in Obese Patients
Pablo Sepúlveda and Ignacio Cortínez
25. Pharmacokinetics and Dynamics on the Pediatric Population
Brian J. Anderson
26. Clinical Pharmacology of Intravenous Sedation in Children
Oliver Bagshaw
27. Sedation of the Critically Ill Child
Arno Brouwers, Sanne Vaassen, Gijs D Vos, Jan NM Schieveld, and Piet L Leroy
28. TCI & TIVA for Neurosurgery: Considerations and Techniques
Massimo Lamperti and Fazil Ashiq
29. TCI in Special Patients Groups: The Elderly and Obese
Frederique S Servin
30. TIVA for Cardiac Surgery
Stefan Schraag
31. TIVA/TCI in Veterinary Practice
Thierry Beths
PART 6. OUTCOME, EDUCATION, SAFETY, AND THE FUTURE
32. Advantages, Disadvantages, and Risks of TIVA/TCI
Ken B Johnson
33. Economics of TIVA
Jane Montgomery and Mary Stocker
34. Teaching TCI with Human Patient Simulators
Wolfgang Heinrichs
35. Closed-Loop or Automated Titration of Intravenous Anesthesia: Background, Science and Clinical Impact
Ngai Liu
36. Health Care Technology, the Human-Machine Interface, and Patient Safety During Intravenous Anesthesia
Craig S. Webster
37. Can IV Sedatives Affect Outcome?
Christopher G. Hughes, Christina J. Hayhurst, and Pratik P. Pandharipande
38. The Benefit and Future of Pharmacogenetics
Janko Samardzic, Dubravka Svob Strac, and John N. van den Anker
39. Lessons from drug interaction displays
Ross Kennedy
40. The Role of Intravenous Agents in Delirium
Claudia Spies, Susanne Koch, Alissa Wolf, Rudolf Mörgeli, and Björn Weiss
41. Perioperative Cardioprotective Strategies in Noncardiac Surgery
Stefan De Hert
42. Opioid Induced Hyperalgesia after Surgery: Clinical Relevance
Dr. Philippe Richebe
43. Memory, Awareness and Intravenous Anaesthetics
Michael Wang
44. Awareness and Dreaming During TIVA
Kate Leslie
45. Apoptosis and Neurocognitive Effects of Intravenous Anesthetics
Sulipicio Soriano and Laszlo Vutskits
Epilogues
