Description
Book SynopsisA single source for accurate scientific information on herbal remedies!
This comprehensive handbook (comprised of two volumes of 700+ pages each) provides a snapshot of 160 herbal products that have been tested in clinical trials. Details of the products and the clinical trials they underwent are here in an easy-to-read, at-a-glance format.
Each botanical profile in The Handbook of Clinically Tested Herbal Remedies contains a summary section (table, text and references), followed by product information and clinical trials for that particular product. An evaluation of the strength of the evidence from the trials, along with the context for therapeutics is included to give you a complete picture of each remedy and its usefulness or lack thereof. If there is more than one product based on a particular botanical then the trials are grouped according to the product.
This valuable book also makes purchasing easy with manufacturer contact information. With o
Table of ContentsVOLUME 1
- About the Editor
- Contributors
- Preface
- Acknowledgments
- Editor’s Note
- PART I: FUNDAMENTALS OF HERBAL MEDICINE
- Chapter 1. History and Regulation of Botanicals in the United States (Loren D. Israelsen and Marilyn Barrett)
- Introduction
- History
- DSHEA Explained
- Drugs: OTC and Rx
- Prospectus
- Chapter 2. Product Definition Deficiencies in Clinical Studies of Herbal Medicines (Varro E. Tyler)
- Chapter 3. Identifying and Characterizing Botanical Products (Marilyn Barrett)
- Identifying Plants by Name
- Means of Assuring Plant Identity
- Preparations and Formulations
- Dose
- Bioavailability
- Guidelines
- Appendix: Preparations and Formulations
- Chapter 4. Standardization of Botanical Preparations: What It Does and Does Not Tell Us (Uwe Koetter and Marilyn Barrett)
- Introduction
- Standardization of Therapeutic Activity
- Standardization to Meet a Chemical Norm
- Standardization As a Reflection of Quality Assurance Programs
- Guidance
- Situation in the Marketplace
- Perspective
- Chapter 5. The Importance and Difficulty in Determining the Bioavailability of Herbal Preparations (Anton Biber and Friedrich Lang)
- Chapter 6. Borrowed Science and Phytoequivalence: Can Two Herbal Products Be Judged Equivalent? (Marilyn Barrett)
- Chemical or Pharmaceutical Equivalency
- Bioequivalency or Therapeutic Equivalency
- Application of the Concepts, Ginkgo As an Example
- Meta-Analyses
- Perspective
- Chapter 7. Determining Efficacy of Herbal Preparations (Tieraona Low Dog)
- Observational Medicine
- Evidence-Based Medicine
- Summary
- Chapter 8. Evaluating Safety of Herbal Preparations (Ezra Béjar, Joseph M. Betz, and Marilyn Barrett)
- Evaluation of Safety
- Adverse Reactions
- Adverse-Event Reporting Systems
- Categorization According to the Degree of Safety
- Product Quality As an Aspect of Safety
- Contraindications
- Drug-Herb Interactions
- Improving Our Knowledge of Safety
- Chapter 9. Conducting Clinical Trials on Herbal Dietary Supplements in North America: Commercialization, Confidence, and Conflicts (Anthony L. Almada)
- The Spirit to Sponsor: Is There an Adequate Economic Incentive to Fund Research?
- Extracting Value from Science
- Competitor Kevlar: Preventing Piracy of Product-Specific Data
- How Much Data Is Enough?
- We Have DataNow What?
- Who Has Science and How Did They Acquire It?
- Conclusion
- Chapter 10. Motives for Conducting Clinical Trials on Botanicals in Europe: A Focus on Germany (Joerg Gruenwald and Stefan Spiess)
- Chapter 11. Pharmacopoeias and Botanical Monographs (Marilyn Barrett, Roy Upton, and V. Srini Srinivasan)
- United States Pharmacopeia and National Formulary (USP-NF)
- American Herbal Pharmacopoeia (AHP) and Therapeutic Compendium
-
- European Pharmacopoeia (EP)
- British Herbal Pharmacopoeia (BHP) and British Herbal Compendium (BHC)
- German Commission E
- European Scientific Cooperative of Phytotherapy (ESCOP)
- Chinese Pharmacopoeia
- African Pharmacopoeia
-
- The Pharmacopoeia of Japan
- The Pharmacopoeias of India
- World Health Organization (WHO)
- Other Pharmacopoeias
- Summary and Perspective
- Sources of Pharmacopoeias
- PART II: METHODS
- Chapter 12. Methods of Product and Trial Inclusion and Evaluation (Marilyn Barrett)
- Gathering Information on Products and Trials
