Description
Book SynopsisOne of the most exciting developments in medicine in this century has been the discovery of opioid receptors and their pharmacology. The breadth of know- edge derived from such discovery has truly changed the practice of medicine today. The acceptance by the clinicians of the research data obtained by the basic scientist on spinal opioids is truly amazing. The clinical sequelae of the discovery of opioid receptors has been the development of the technique of intraspinal administration of opioids. In the last decade much has been written about indications, effects, and side effects of intraspinal opioids. The technique has become commonplace for cancer and postoperative pain. However, no standards of care and management of patients with spinally administered opioids have been developed. We need these standards to be developed and universally followed. The monograph was conceived t
Table of Contents1. Opioid receptors: Types, distribution, and pharmacological profiles.- 2. Systemic and local distribution of opioids after spinal administration: Implications for their clinical use.- 3. Indications for the use of intraspinal opioids.- 4. Perioperative stress reduction with intraspinal opioids.- 5. Adverse effects of spinal opioids in acute pain and their management.- 6. The role of intraspinal opioids in obstetrics.- 7. Delivery systems for chronic spinal analgesia.- 8. Spinal opioid analgesia: Present status and future developments.