Description
Book SynopsisThis comprehensive volume provides an homogeneous coverage of the whole area of solid-phase synthesis/combinatorial technology and clarifies the strategies used to plan, design, prepare and test combinatorial libraries.
Trade Review"For both experienced combinatorial chemists and newcomers ...Seneci...provides an overview of recent developments in the realm where chemistry intersects with automation, statistics, information science, and certain biological disciplines." (SciTech Book News, Vol. 25, No. 2, June 2001)
"...[a] comprehensive review of the whole combinatorial area" (Chemistry in Britain, January 2001)
"...a welcome addition to the rapidly developing field of combinatorial synthetic chemistry..." (Pharmaceutical Research, Vol. 18, No. 9, September 2001)
Table of ContentsSolid-Phase Synthesis: Basic Principles.
Solid-Phase Synthesis: Oligomeric Molecules.
Solid-Phase Synthesis: Small Organic Molecules.
Combinatorial Technologies: Basic Principles.
Synthetic Organic Libraries: Library Design and Properties.
Synthetic Organic Libraries: Solid-Phase Discrete Libraries.
Synthetic Organic Libraries: Solid-Phase Pool Libraries.
Synthetic Organic Libraries: Solution-Phase Libraries.
Applications of Synthetic Libraries.
Biosynthetic Combinatorial Libraries.
Materials and Polymeric Combinatorial Libraries.
Index.