Description

Book Synopsis

RNA therapeutics: Bridging discovery and clinical implementation.- Molecular mechanisms of innate immune sensing of exogenous RNAs.- Chemical modifications in nucleic acid therapeutic.- Effects of nucleoside modifications on mRNA Translation: Choosing the right modifications.- Generation of lipid nanoparticle mRNA vaccines and evaluation of antigen specific CD8+ T cell responses.- Assessing the immunogenicity of synthetic RNA using blood cells.- Lateral flow immunoassay for rapid and sensitive detection of dsRNA contaminants in in vitro-transcribed mRNA products.- Hydrophobic chromatography purification of linearized Plasmid DNA reduces dsRNA formation during in vitro transcription.- Optimization of In vitro transcription reaction for mRNA production using chromatographic at-line monitoring.- Large scale production of unmodified mRNA for reprogramming human dendritic cells and T cells.- Production of mRNA-loaded dendritic cell cancer vaccines.- Enhancing cancer vaccine efficacy: siRNA-based modulation of immune suppressive factors in dendritic cells.- mRNA-based engineering of viral antigen-specific TCR-T cells.- Engineering mRNA CAR-T cells for cancer immunotherapy.- Generating mRNA encoding anti-HBV designer epigenome modifiers.- Lipid nanoparticles for the delivery of mRN.- Optimization of DOTAP/cholesterol cationic lipid nanoparticles for nucleic acid delivery.- Formulation and characterization of cationic bicelles for siRNA delivery.- Bioinspired extracellular vesicles for enhanced delivery of siRNA to tumours.- Construction of nanotube-shaped mRNA vehicles using self-assembling peptides.- Nanoparticle-mediated siRNA delivery in human epithelial lung cells cultured at the air-liquid interface.- Developing aptamer-targeted mRNA for immunotherapy.- A facile method for assessing cellular stability and co-localization of Cas9 mRNA and sgRNA using confocal microscopy.- siRMSD: A structural parameter to reduce sequence-dependent off-target effects for siRNA design with chemical modifications.- Chemical strategies to enhance antisense strand selection and minimize off-target effect-mediated by siRNAs.- In vivo fermentation production of RNA interference agents.

RNA Therapeutics

    Product form

    £151.99

    Includes FREE delivery

    RRP £159.99 – you save £8.00 (5%)

    Order before 4pm tomorrow for delivery by Wed 17 Jun 2026.

    A Hardback by Mouldy Sioud

    Out of stock


      View other formats and editions of RNA Therapeutics by Mouldy Sioud

      Publisher: Humana
      Publication Date: 05/09/2025
      ISBN13: 9781071647417, 978-1071647417
      ISBN10:
      Also in:
      Materials science

      Description

      Book Synopsis

      RNA therapeutics: Bridging discovery and clinical implementation.- Molecular mechanisms of innate immune sensing of exogenous RNAs.- Chemical modifications in nucleic acid therapeutic.- Effects of nucleoside modifications on mRNA Translation: Choosing the right modifications.- Generation of lipid nanoparticle mRNA vaccines and evaluation of antigen specific CD8+ T cell responses.- Assessing the immunogenicity of synthetic RNA using blood cells.- Lateral flow immunoassay for rapid and sensitive detection of dsRNA contaminants in in vitro-transcribed mRNA products.- Hydrophobic chromatography purification of linearized Plasmid DNA reduces dsRNA formation during in vitro transcription.- Optimization of In vitro transcription reaction for mRNA production using chromatographic at-line monitoring.- Large scale production of unmodified mRNA for reprogramming human dendritic cells and T cells.- Production of mRNA-loaded dendritic cell cancer vaccines.- Enhancing cancer vaccine efficacy: siRNA-based modulation of immune suppressive factors in dendritic cells.- mRNA-based engineering of viral antigen-specific TCR-T cells.- Engineering mRNA CAR-T cells for cancer immunotherapy.- Generating mRNA encoding anti-HBV designer epigenome modifiers.- Lipid nanoparticles for the delivery of mRN.- Optimization of DOTAP/cholesterol cationic lipid nanoparticles for nucleic acid delivery.- Formulation and characterization of cationic bicelles for siRNA delivery.- Bioinspired extracellular vesicles for enhanced delivery of siRNA to tumours.- Construction of nanotube-shaped mRNA vehicles using self-assembling peptides.- Nanoparticle-mediated siRNA delivery in human epithelial lung cells cultured at the air-liquid interface.- Developing aptamer-targeted mRNA for immunotherapy.- A facile method for assessing cellular stability and co-localization of Cas9 mRNA and sgRNA using confocal microscopy.- siRMSD: A structural parameter to reduce sequence-dependent off-target effects for siRNA design with chemical modifications.- Chemical strategies to enhance antisense strand selection and minimize off-target effect-mediated by siRNAs.- In vivo fermentation production of RNA interference agents.

      Recently viewed products

      © 2026 Book Curl

        • American Express
        • Apple Pay
        • Diners Club
        • Discover
        • Google Pay
        • Maestro
        • Mastercard
        • PayPal
        • Shop Pay
        • Union Pay
        • Visa

        Login

        Forgot your password?

        Don't have an account yet?
        Create account