Description
Book SynopsisThis volume presents a snapshot of some of the most important ongoing research in cancer. With cancer as the second leading cause of death worldwide, extensive research is going on globally to decipher the molecular mechanism underlying cancer that will help in finding better targets for drug therapy. The book brings together new research on molecular mechanism and cancer therapeutics in one place. With chapters from experts in their respective fields, chapters cover molecular mechanisms, etiology, prognosis, detection, and treatment of cancer. Emphasis has been given to the intricate mechanism behind the deregulation of cell division, disruption of cell cycle check points, mutation in oncogenes and tumor suppressor genes, apoptosis, and erratic cell signaling. The book discusses in detail topics such as angiogenesis and tumor microenvironment, which are increasingly receiving attention, especially in the field of neoplastic vascularization and metastasis. The book also includes chapters detailing the current understanding and the future perspective of cancer stem cells.
Trade Review“One of the few books that sheds light on the causes and mechanisms of the disease itself as well as the possible therapeutic aspects. The book contains intricately woven chapters on cell cycle checkpoints on cancer, oncogenes, tumor suppressor genes, apoptosis, cell signaling, angiogenesis and metastasis. The modern approaches toward cancer diagnosis and therapy, like cancer stem cell, immunotherapy, chemotherapy, and nanoparticle-based therapy, have also been thoroughly covered. The contributors of each and every chapter are experts in their respective field and have summarized their research findings in a very concise manner. The best part of the book is that the chapters have been grouped into major divisions to have continuity and synchronization among them. The volume can be used by students and researchers who are working in the field of cancer. It covers new approaches toward cancer treatment and therefore may be useful handbook for clinicians. Overall, this informative volume covers the present knowledge and future direction on the field of cancer research.”
— Dr. Naibedya Chattopadhyay, Scientist G, CSIR-Central Drug Research Institute, Lucknow, India
Table of ContentsGenetic Instability in Cancer. Oncogenesis and Telomerase Activity in Cancer. Cell Cycle Checkpoints in Cancer. Angiogenesis, Its Importance and Implication in Tumor Growth and Progression and in Anticancer Therapy: An Update. The Tumor Microenvironment and Metastasis. Apoptosis: A Regulatory Mechanism in Cancer. Cytoplasmic Signaling Circuitry: An Important Trait of Cancer. Cancer: An Overview of Risk Factors. Single Nucleotide Polymorphisms as Susceptibility Markers for Cancer. Dietary Phytochemicals in the Prevention and Therapy of Cancer: Modulation of Molecular Targets. Health Benefits and Preventive Effects of Common Beverages in Cancer. Cancer Chemotherapy. Non-Coding RNAs: The New Reins in Malignancies. Epigenetics in Cancer Prevention and Therapy: Role of Phytochemicals. Cancer Stem Cell: Current Understanding and Future Perspectives. Tumor Microenvironment and Cancer Stem Cells: Therapeutic Potential of Epigenetic Inhibitors to Target CSCs. Nanoparticles in Cancer Therapy. Cancer Immunotherapy: Extending New Horizons in Cancer Treatment.
