Description
Book SynopsisProtein-mediated charge transport is of relevant importance in the design of protein-based electronics and in attaining an adequate level of understanding of protein functioning. This book reviews a variety of experiments devoted to the investigation of charge transport in proteins and presents a unified theoretical model to interpret macroscopic results in terms of the amino acids backbone-structure of the single protein. It aims to serve a broad audience of researchers involved in the field of electrical characterization of biological materials and in the development of new molecular devices based on proteins and also as a reference platform that surveys existing data and presents the basis for future development of a new branch of nano-electronics, which by mixing proteomics, that is, the large-scale study of proteins, particularly their structures and functions, and electronics is introduced here as proteotronics.
Trade Review"This book presents the first structured approach to the new field of protein-based electronics, which has opened possibilities for the development of new concepts of nanobiosensors for health applications. It presents a solid theoretical approach which is validated by the existing experimental evidence, and will be of relevance for both young and experienced researchers who are interested in the frontier between electronics and biology."
— Prof. Joan Bausells, Barcelona Microelectronics Institute (CSIC), Spain
"This book presents a newly emerging discipline, proteotronics, investigating the coupling between the protein world and electronics. It opens the field of protein-based nanobiosensors that are able to bypass the complicated sequence of biological events for signal generation in e-sensing."
— Prof. Nicole Jaffrezic-Renault, Institute of Analytical Chemistry, University of Lyon, France
"Alfinito and her coworkers have made the very first steps of analyzing the electrical transport characteristics of the building elements of potentially important protein-based electronics. Highly recommended reading for all those who are involved with these developments and anybody who is interested in these challenging issues."
— Prof. Lazlo B. Kish, Texas A&M University, USA
Table of ContentsPreface. Introduction. Sensing Proteins. Electrical Properties: Experiments. Electrical Properties: Theory. Bacteriorhodopsin as Testing Prototype. Survey of Other Proteins. Conclusion and Perspectives. Appendix: Computational Details. List of acronyms. Bibliography. Index.
