Description
Book SynopsisBridging the knowledge gap between scientists that develop and apply proteomics technologies and oncologists who focus on understanding the biological basis behind cancer manifestation and progression, this title provides an account of how the multiple facets of proteomics have been applied to cancer.
Trade Review“By guiding readers through the latest proteomic technologies and their applications in cancer research, “Proteomic Applications in Cancer Detection and Discovery" enhances the ability of researchers in proteomics and researchers in oncology to collaborate in order to better understand cancer and develop strategies to prevent and treat it.” (Newbooks.lib, 11 September 2014
Table of ContentsPreface vii
Acknowledgments ix
1 Systems Biology 1
2 Mass Spectrometry in Cancer Research 27
3 Quantitative Proteomics 59
4 Proteomic Analysis of Posttranslational Modifications 87
5 Characterization of Protein Complexes 117
6 Global Phosphorylation Analysis 145
7 the Search for Biomarkers in Biofluids 171
8 Proteomic Patterns: a New Paradigm in Diagnostics And Therapeutics? 195
9 the Emergence of Protein Arrays 215
10 the Role of Proteomics in Personalized Medicine 241
11 the Critical Role of Bioinformatics 263
12 Future Prospects of Proteomics in Cancer Research 281
Index 305
