Description

Book Synopsis
Highly Commended at the British Medical Association Book Awards 2016 Postgraduate Haematology provides up-to-date knowledge of the pathogenesis, clinical and laboratory features, management and treatment of a wide range of blood and bone marrow disorders in a concise and user friendly style.

Table of Contents

Contributor List vii

Preface to the Seventh Edition x

Preface to the First Edition xi

1 Stem cells and haemopoiesis 1
Emma de Pater, Elaine Dzierzak

2 Erythropoiesis 11
Douglas R Higgs, Noémi Roy, Deborah Hay

3 Iron metabolism, iron deficiency and disorders of haem synthesis 21
Clara Camaschella, A Victor Hoffbrand, Chaim Hershko

4 Iron overload 40
Clara Camaschella, A Victor Hoffbrand, Maria Domenica Cappellini

5 Megaloblastic anaemia 53
A Victor Hoffbrand

6 Haemoglobin and the inherited disorders of globin synthesis 72
Swee Lay Thein, David Rees

7 Sickle cell disease 98
Anne Marsh, Elliott P Vichinsky

8 Hereditary disorders of the red cell membrane and disorders of red cell metabolism 114
Paola Bianchi, Narla Mohandas

9 Acquired haemolytic anaemias 138
Modupe O Elebute, Rachel Kesse-Adu

10 Inherited aplastic anaemia/bone marrow failure syndromes 156
Inderjeet S Dokal

11 Acquired aplastic anaemia and paroxysmal nocturnal haemoglobinuria 174
Judith CW Marsh, Austin G Kulasekararaj, Neal S Young, Peter Hillmen

12 Red cell immunohaematology 195
Geoff Daniels, Marcela Contreras, Shubha Allard

13 Clinical blood transfusion 214
Shubha Allard, Marcela Contreras

14 Phagocytes 246
John Mascarenhas, Marina Kremyanskaya, Ronald Hoffman

15 Lysosomal storage disorders 270
Atul B Mehta, Derralynn A Hughes

16 Normal lymphocytes and non-neoplastic lymphocyte disorders 278
Paul Moss, Mark Drayson

17 The spleen 303
Paul Moss

18 The molecular basis of haematological malignancies 314
Niccolo Bolli, George Vassiliou

19 Laboratory diagnosis of haematological neoplasms 332
Torsten Haferlach, Barbara J Bain

20 Acute myeloid leukaemia 352
Alan K Burnett, David Grimwade

21 Adult acute lymphoblastic Llukaemia 371
Clare J Rowntree, Adele K Fielding

22 Childhood acute lymphoblastic leukaemia 384
Ajay Vora

23 Supportive care in the management of leukaemia 399
Eliza Gil, Vanya Gant, Panagiotis Kottaridis

24 Chronic myeloid leukaemia 419
David TO Yeung, Timothy P Hughes

25 The myelodysplastic syndromes 438
Kavita Raj, Ghulam J Mufti

26 Myeloproliferative neoplasms 474
Peter J Campbell, Claire Harrison, Anthony R Green

27 Chronic lymphocytic leukaemia and other chronic B-cell disorders 500
Emili Montserrat, Peter Hillmen

28 T-cell lymphoproliferative disorders 524
Pier Luigi Zinzani, Alessandro Broccoli

29 Multiple myeloma 537
Jesús San-Miguel, Joan Bladé

30 Amyloidosis 562
Simon DJ Gibbs, Philip N Hawkins

31 The classification of lymphomas: updating the WHO classification 575
Elias Campo, Stefano A Pileri

32 Hodgkin lymphoma 601
Piers Blombery, David Linch

33 Non-Hodgkin lymphoma: low grade 614
William Townsend, Robert Marcus

34 Non-Hodgkin lymphoma: high grade 631
Jessica Okosun, Kate Cwynarski

35 Stem cell transplantation 651
Charles Craddock, Ronjon Chakraverty

36 Normal haemostasis 676
Keith Gomez, John H McVey

37 The vascular function of platelets 699
Stephen P Watson, Neil V Morgan, Paul Harrison

38 Haemophilia and Von Willebrand disease 715
Michael A Laffan, K John Pasi

39 Rare inherited coagulation disorders 733
Flora Peyvandi, Marzia Menegatti

40 Acquired coagulation disorders 743
Peter W Collins, Jecko Thachil, Cheng-Hock Toh

41 Congenital platelet disorders 761
Maurizio Margaglione, Paul RJ Ames

42 Primary immune thrombocytopenia 773
Drew Provan, Adrian C Newland

43 Thrombotic thrombocytopenic purpura and haemolytic–uraemic syndrome (congenital and acquired) 783
Pier Mannuccio Mannucci, Flora Peyvandi, Roberta Palla

44 Heritable thrombophilia 795
Trevor Baglin, David Keeling

45 Acquired venous thrombosis 809
Beverley J Hunt, Henry G Watson

46 Antithrombotic agents 820
Trevor Baglin, David Keeling

47 Management of venous thromboembolism 830
Trevor Baglin, David Keeling

48 Haematologicalaspectsofsystemicdisease 838
A Victor Hoffbrand, Atul B Mehta

49 Haematological aspects of tropical diseases 854
Imelda Bates, Ivy Ekem

50 Neonatal haematology 870
Irene Roberts, Subarna Chakravorty

51 WHO Classification: Tumours of the Haematopoietic and Lymphoid Tissues (2008) 885

Index 888

Postgraduate Haematology

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    A Hardback by Victor Hoffbrand, Douglas R. Higgs, David M. Keeling

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      View other formats and editions of Postgraduate Haematology by Victor Hoffbrand

      Publisher: John Wiley and Sons Ltd
      Publication Date: Publication Date: 01/01/2016
      ISBN13: 9781118854327, 978-1118854327
      ISBN10: 1118854322

      Description

      Book Synopsis
      Highly Commended at the British Medical Association Book Awards 2016 Postgraduate Haematology provides up-to-date knowledge of the pathogenesis, clinical and laboratory features, management and treatment of a wide range of blood and bone marrow disorders in a concise and user friendly style.

      Table of Contents

      Contributor List vii

      Preface to the Seventh Edition x

      Preface to the First Edition xi

      1 Stem cells and haemopoiesis 1
      Emma de Pater, Elaine Dzierzak

      2 Erythropoiesis 11
      Douglas R Higgs, Noémi Roy, Deborah Hay

      3 Iron metabolism, iron deficiency and disorders of haem synthesis 21
      Clara Camaschella, A Victor Hoffbrand, Chaim Hershko

      4 Iron overload 40
      Clara Camaschella, A Victor Hoffbrand, Maria Domenica Cappellini

      5 Megaloblastic anaemia 53
      A Victor Hoffbrand

      6 Haemoglobin and the inherited disorders of globin synthesis 72
      Swee Lay Thein, David Rees

      7 Sickle cell disease 98
      Anne Marsh, Elliott P Vichinsky

      8 Hereditary disorders of the red cell membrane and disorders of red cell metabolism 114
      Paola Bianchi, Narla Mohandas

      9 Acquired haemolytic anaemias 138
      Modupe O Elebute, Rachel Kesse-Adu

      10 Inherited aplastic anaemia/bone marrow failure syndromes 156
      Inderjeet S Dokal

      11 Acquired aplastic anaemia and paroxysmal nocturnal haemoglobinuria 174
      Judith CW Marsh, Austin G Kulasekararaj, Neal S Young, Peter Hillmen

      12 Red cell immunohaematology 195
      Geoff Daniels, Marcela Contreras, Shubha Allard

      13 Clinical blood transfusion 214
      Shubha Allard, Marcela Contreras

      14 Phagocytes 246
      John Mascarenhas, Marina Kremyanskaya, Ronald Hoffman

      15 Lysosomal storage disorders 270
      Atul B Mehta, Derralynn A Hughes

      16 Normal lymphocytes and non-neoplastic lymphocyte disorders 278
      Paul Moss, Mark Drayson

      17 The spleen 303
      Paul Moss

      18 The molecular basis of haematological malignancies 314
      Niccolo Bolli, George Vassiliou

      19 Laboratory diagnosis of haematological neoplasms 332
      Torsten Haferlach, Barbara J Bain

      20 Acute myeloid leukaemia 352
      Alan K Burnett, David Grimwade

      21 Adult acute lymphoblastic Llukaemia 371
      Clare J Rowntree, Adele K Fielding

      22 Childhood acute lymphoblastic leukaemia 384
      Ajay Vora

      23 Supportive care in the management of leukaemia 399
      Eliza Gil, Vanya Gant, Panagiotis Kottaridis

      24 Chronic myeloid leukaemia 419
      David TO Yeung, Timothy P Hughes

      25 The myelodysplastic syndromes 438
      Kavita Raj, Ghulam J Mufti

      26 Myeloproliferative neoplasms 474
      Peter J Campbell, Claire Harrison, Anthony R Green

      27 Chronic lymphocytic leukaemia and other chronic B-cell disorders 500
      Emili Montserrat, Peter Hillmen

      28 T-cell lymphoproliferative disorders 524
      Pier Luigi Zinzani, Alessandro Broccoli

      29 Multiple myeloma 537
      Jesús San-Miguel, Joan Bladé

      30 Amyloidosis 562
      Simon DJ Gibbs, Philip N Hawkins

      31 The classification of lymphomas: updating the WHO classification 575
      Elias Campo, Stefano A Pileri

      32 Hodgkin lymphoma 601
      Piers Blombery, David Linch

      33 Non-Hodgkin lymphoma: low grade 614
      William Townsend, Robert Marcus

      34 Non-Hodgkin lymphoma: high grade 631
      Jessica Okosun, Kate Cwynarski

      35 Stem cell transplantation 651
      Charles Craddock, Ronjon Chakraverty

      36 Normal haemostasis 676
      Keith Gomez, John H McVey

      37 The vascular function of platelets 699
      Stephen P Watson, Neil V Morgan, Paul Harrison

      38 Haemophilia and Von Willebrand disease 715
      Michael A Laffan, K John Pasi

      39 Rare inherited coagulation disorders 733
      Flora Peyvandi, Marzia Menegatti

      40 Acquired coagulation disorders 743
      Peter W Collins, Jecko Thachil, Cheng-Hock Toh

      41 Congenital platelet disorders 761
      Maurizio Margaglione, Paul RJ Ames

      42 Primary immune thrombocytopenia 773
      Drew Provan, Adrian C Newland

      43 Thrombotic thrombocytopenic purpura and haemolytic–uraemic syndrome (congenital and acquired) 783
      Pier Mannuccio Mannucci, Flora Peyvandi, Roberta Palla

      44 Heritable thrombophilia 795
      Trevor Baglin, David Keeling

      45 Acquired venous thrombosis 809
      Beverley J Hunt, Henry G Watson

      46 Antithrombotic agents 820
      Trevor Baglin, David Keeling

      47 Management of venous thromboembolism 830
      Trevor Baglin, David Keeling

      48 Haematologicalaspectsofsystemicdisease 838
      A Victor Hoffbrand, Atul B Mehta

      49 Haematological aspects of tropical diseases 854
      Imelda Bates, Ivy Ekem

      50 Neonatal haematology 870
      Irene Roberts, Subarna Chakravorty

      51 WHO Classification: Tumours of the Haematopoietic and Lymphoid Tissues (2008) 885

      Index 888

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