Description
Book SynopsisDescribing recent developments in the engineering and generation of plants as production platforms for biopharmaceuticals, this book includes both vaccines and monoclonal antibodies. It has a particular emphasis on targeting diseases which predominate in less developed countries, encompassing the current state of technologies and describing expression systems and applications. This book also includes a variety of vaccine case studies, protecting against pervasive infectious diseases such as rabies, influenza and HIV.
Table of Contents1: Introduction, and the Promise of a Plant-derived Vaccine for Hepatitis B Virus 2: Protein Body-inducing Fusions for Recombinant Protein Production in Plants 3: Expression of Recombinant Proteins in Plant Cell Culture 4: Plant-derived Monoclonal Antibodies as Human Biologics for Infectious Disease and Cancer 5: Plant-produced Virus-like Particles 6: Expression of the Capsid Protein of Human Papillomavirus in Plants as an Alternative for the Production of Vaccines 7: Patenting of Plant-made Recombinant Pharmaceuticals and Access in the Developing World 8: Case Study 1: Rabies 9: Case Study 2: Plant-made HIV Vaccines and Neutralizing Antibodies 10: Case Study 3: The Search for a Plant-made Vaccine for Pandemic Influenza Virus