Description
Book SynopsisObesity is one of the most relevant public health concerns today and it is now evident that body weight control is achieved through highly integrated physiological interactions like nutrient selection as well as being influenced by genetic and environmental factors. Moreover, energy balance regulation is a complex process aimed at maintaining constant energy stores. Presenting a detailed and comprehensive account of the roles of specific peptides in energy balance, food intake control and co-morbidities, this review provides a better understanding of the patho-physiology of energy balance and obesity.
Table of ContentsSection 1: Central pathways involved in the control of food intake and energy expenditure 1: Orexigenic neuropeptides: Hypothalamic regulation of appetite 2: Anorexigenic peptides 3: Newcomers and supporting actors Section 2: Peripheral signals participating in energy homeostasis and obesity: associated alterations 4: The gut as a second brain 5: The adipo-hepato-insular axis in glucose homeostasis 6: Elements of the adipostat 7: Adipocytokines participating in the immune-stress response 8: Peptides involved in vascular homeostasis 9: Natriuretic peptides and other lipolytic peptides involved in the control of lipid mobilization Section 3: Integrative Perspectives 10: Hierarchy of neural pathways controlling energy homeostasis 11: Relevance of reward signals in the homeostatic control of energy balance 12: Overview of the Integrative physiology of adipose tissue in energy homeostasis 13: Is the energy homeostasis system inherently biased toward weight gain? A teleological molecular physiological and clinical view 14: Embracing complexity: The emergence of functional neuroimaging and other methodologies to study the role of the human brain in the pathophysiology of obesity. 15: Application of ""OMICS"" strategies to obesity research 16: Implications for the future of obesity management"
