Description
Book SynopsisThe subject matter in this volume was derived from papers presented at the Pediatric Andrology session of the 1st Pan American Congress of Andrology held in Caracas, Venezuela in February 1979, as well as from selected additional manuscripts of interest in this field. Prior to this session, identification of a distinct discipline and specialty devoted to pediatric andrology had not occurred, nor had it been conceptualized. Pediatric andrology encompasses many different areas: disorders of sexual development, structural disease of the genital organs, normal and abnormal puberty, undescended testes, genital tumors, gonadal function and its relationship to growth, virilization, fertility and gender identity all represent areas of specific interest, to name but a few. Andrology itself is a unique field, bringing together clinicians and basic scientists with diverse back grounds. It should be noted that between one-half and three-quarters of the clinicians contributing to this issue conduct basic research as well. It has been this unique blend of basic research and clinical medicine which has done much to unravel many of these problems characteristic of this field.
Table of Contents1. Sex differentiation of male genitalia.- 2. The fetal hormonal environment and its effect on the morphogenesis of the genital system.- 3. Stromal influence on expression of morphological and functional characteristics of urogenital epithelia.- 4. Biochemistry and biology of Müllerian Inhibiting Substance.- 5. Control of Müllerian Inhibiting Substance.- 6. Ontogeny of 5?-reductase and the androgen receptor in the penis.- 7. Studies on H-Y antigen: The genetic basis of abnormal gonadal differentiation.- 8. Abnormal sexual development: A classification with emphasis on pathology and neoplastic conditions.- 9. Male pseudohermaphroditism due to abnormal testosterone biosynthesis and metabolism.- 10. The impact of androgens on the evolution of male gender identity.- 11. Sexual differentiation of the brain.- 12. Gender identity/role (G-I/R) in male hermaphroditism.- 13. Pathogenesis of cryptorchidism.- 14. Gonadotropin therapy for the undescended testis.- 15. Congenital anomalies of the vas deferens and epididymis.- 16. Leydig cells tumor and their distinction from testicular tumors associated with congenital adrenal hyperplasia.- 17. Lower urinary tract morphology in patients with hypospadias.- 18. Micropenis: etiologic and management considerations.- Concluding remarks.
