Description

Book Synopsis
Paraneoplastic Syndromes (PNS) are a group of disorders that cause endocrinologic, hematologic, neurologic, and dermatologic manifestations of cancer. These conditions are not directly caused by tumour metastasis, but rather the malignancies produce hormones and other proteins which act to disrupt the body''s homeostasis, thereby causing symptoms. The neurological complications of PNS are the result of an immune response to tumour antigens. PNS have been associated with a variety of cancers, such as genitourinary, ovarian, and breast, but are most commonly associated with neuroendocrine tumours. These syndromes can even occur before the primary tumour is identified. Historically, these conditions were considered rare, but given the difficulties with diagnosis, the exact prevalence is unknown. This book focuses on the symptoms, diagnosis, and treatment of PNS. More specifically, it discusses current concepts in common PNS; cutaneous PNS and skin features of internal malignancy; PNS in patients with malignancies of the genitourinary tract; PNS polyneuropathies; the correction of cancer-related anemai with oxyresveratrol; and PNS associated with lung cancer.

Paraneoplastic Syndromes: Symptoms, Diagnosis &

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    A Hardback by Lora H Winter

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      Book details

      Publisher Nova Science Publishers Inc
      Published 1 June 2014
      ISBN-13 9781631178788
      978-1631178788
      ISBN-10 1631178784
      Also in:
      Oncology

      Description

      Book Synopsis
      Paraneoplastic Syndromes (PNS) are a group of disorders that cause endocrinologic, hematologic, neurologic, and dermatologic manifestations of cancer. These conditions are not directly caused by tumour metastasis, but rather the malignancies produce hormones and other proteins which act to disrupt the body''s homeostasis, thereby causing symptoms. The neurological complications of PNS are the result of an immune response to tumour antigens. PNS have been associated with a variety of cancers, such as genitourinary, ovarian, and breast, but are most commonly associated with neuroendocrine tumours. These syndromes can even occur before the primary tumour is identified. Historically, these conditions were considered rare, but given the difficulties with diagnosis, the exact prevalence is unknown. This book focuses on the symptoms, diagnosis, and treatment of PNS. More specifically, it discusses current concepts in common PNS; cutaneous PNS and skin features of internal malignancy; PNS in patients with malignancies of the genitourinary tract; PNS polyneuropathies; the correction of cancer-related anemai with oxyresveratrol; and PNS associated with lung cancer.

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