Description
Book SynopsisFocusing on the redox regulation of cell signaling responsible for oxidative stress and inflammatory tissue damage, this reference presents a comprehensive overview of research on the intracellular events mediating or preventing oxidative stress and pro-inflammatory processes induced by endogenous and xenobiotic factors.
Table of ContentsOxidants and Antioxidants: Mechanism of Action and Regulation of Gene Expression by Bio?avonoids. Transcriptional Regulation of Cellular Antioxidant Defense Mechanisms. Redox Regulation of In?ammatory Tissue Damage by Thioredoxin. Regulation of NF-kB-Driven In?ammatory Genes by Phytoestrogens. Nuclear Factor-kB as Target for Chemoprevention. Heme Oxygenase-1: An Emerging Major Cellular Defense Against Cigarette Smoke-Induced Oxidative Stress and Cytotoxicity. Biphasic Induction of HO-1 in Macrophages Treated with Lipopolysaccharide: Role of HO-1 Induction in Cell Survival from Oxidative Stress. The Role of Ga12 Proteins in the PKC and JNK-Dependent Induction of NOS by Thrombin. Actions of 8-Hydroxyguanine in DNA. Role of Oxidative Stress in Hypercholesterolemia-Induced In?ammation. Oxidative Stress in Rheumatoid Arthritis. Roles of Carbon Monoxide and Nitric Oxide in Liver Damage. Role of Oxidative Stress and In?ammatory Response in Smokers and Chronic Obstructive Pulmonary Disease. Association of Chronic In?ammation with Carcinogenesis: Implications of Anti-In?ammatory Strategies for Cancer Prevention. Molecular In?ammation as an Underlying Mechanism of Aging: The Anti-in?ammatory Action of Calorie Restriction. Oxidative Stress in Mitochondria: The Involvement in Neurodegenerative Diseases. Implications of In?ammatory Stress in Alzheimer's Disease. Biomarkers for Evaluating Antioxidant Effects. Antioxidant and Neuroprotective Potentials. Resveratrol-A Unique Polyphenolic Antioxidant Present in Grape Skins and Red Wine-Is a Preventive Medicine Against a Variety of Degenerative Diseases. Molecular Mechanisms of Prevention Against Allergic Rhinitis by Aller-7, A Novel Polyherbal Formulation. Antioxidant Character of Selenium and Its Survival Signals by Activation of PI3-K/Akt Pathways. Neuroprotection by Rasagiline and Related Propargylamines Is Mediated by Suppression of Mitochondrial Death Signal and Induction of Antiapoptotic Genes. Index.
