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Book Synopsis
Osteoblasts are highly specialised mesenchymal cells that are mainly responsible for the formation and maintenance of the skeletal architecture. They produce extracellular matrix proteins and are regulators of matrix mineralisation during bone formation and remodelling. In this book, the authors discuss the morphology, functions and clinical implications of osteoblasts. Topics include osteoblasts under mechanical strain; mesenchymal stem cells (MSC) into osteoblasts for bone tissue engineering; osteoblast function and their role in skeletal bone diseases; bone morphogenetic proteins (BMP) and osteoblastogenesis inhibitors; the effect of molecular and biochemical differentiation agents on bone formation; and the evaluation of characteristics of osteoblasts and factors related to osteoblastic differentiation and mineralisation.

Osteoblasts: Morphology, Functions & Clinical

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    A Hardback by Hugo Scheurer

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      Publisher: Nova Science Publishers Inc
      Publication Date: 15/04/2013
      ISBN13: 9781624178061, 978-1624178061
      ISBN10: 1624178065
      Also in:
      Musculoskeletal medicine Science & Nature Cellular biology (cytology)

      Description

      Book Synopsis
      Osteoblasts are highly specialised mesenchymal cells that are mainly responsible for the formation and maintenance of the skeletal architecture. They produce extracellular matrix proteins and are regulators of matrix mineralisation during bone formation and remodelling. In this book, the authors discuss the morphology, functions and clinical implications of osteoblasts. Topics include osteoblasts under mechanical strain; mesenchymal stem cells (MSC) into osteoblasts for bone tissue engineering; osteoblast function and their role in skeletal bone diseases; bone morphogenetic proteins (BMP) and osteoblastogenesis inhibitors; the effect of molecular and biochemical differentiation agents on bone formation; and the evaluation of characteristics of osteoblasts and factors related to osteoblastic differentiation and mineralisation.

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