Description
Book SynopsisThe complete mapping of the human genome, along with the development of sophisticated molecular technologies, has accelerated research on the relationship between nutrients and genes. This has led to compelling evidence garnered from epidemiological and experimental observations supporting the idea that the interaction between nutrients and genes is one of the most important mechanisms influencing carcinogenesis.
Nutrient-Gene Interactions in Cancer brings together leading authorities in the field who provide an overview and look specifically at the mechanisms known to underlie each nutrient and gene interaction. The book examines the multi-functional relationship linking nutrition and cancer development, including the complex role nutrients have in modulating cancer growth via interactions with specific genes, and the emerging new strategy for cancer chemoprevention that is based on a deepened understanding of this relationship. The authors also provide freshly illuminating in
Table of ContentsNutrients and Genes Interaction. Candidate Mechanisms for the Nutrients and Gene Interaction. Biomarkers for Nutrients and Gene Interaction. Folate and Methylenetetrahydrofolate Reductase Gene. Folate and One-Carbon Metabolism Genes. Methionine and Methionine Adenosyltransferase. b -Carotene and Retinoic Receptor Genes. Vitamin D and Vitamin D Receptor Gene. Alcohol and Alcohol Dehydrogenase Genes. Meat and N-Acetyltransferase 2 Gene. Dietary Estrogens and Estrogen Receptor Genes. Ferritin and Serine Hydroxymethyltransferase Gene. Isothiocyanate and Glutathione S-Transferase Gene. Future Directions and Implication of Research on Nutrients and Gene Interactions in Cancer.