Description
Book SynopsisWith the invention of scanning probe techniques in the early 1980s, scientists can now play with single atoms, single molecules, and even single bonds. Force, dynamics, and function can now be probed at the single-molecule level. Molecular Manipulation with Atomic Force Microscopy (AFM) presents a series of topics that discuss concepts and methodologies used to manipulate and study single (bio)molecules with AFM. The first part is dedicated to the pulling of single molecules with force spectroscopy to investigate molecular interactions, mechanics, and mechanochemical processes, and the second part to the manipulation, repositioning, and targeted delivery of single molecules on substrates.
Single molecule manipulation is an exciting area of research which made important breakthroughs in nanoscience and which could find potential applications in a diverse range of disciplines, including chemistry, biology, physics, material and polymer science, and engineering.
Trade Review
Single molecule manipulation is an exciting area of research which made important breakthroughs in nanoscience and which could find potential applications in a diverse range of disciplines, including chemistry, biology, physics, material and polymer science, and engineering. New and experienced AFM researchers looking for applications beyond imaging will find a wealth of information in this informative volume.
—Anticancer Research, 32: 715-720 (2012)
Table of ContentsPulling on Single Molecules with Force Spectroscopy:Molecular Recognition Force Spectroscopy. Mechanics of Proteins and Tailored Mechanics of Engineered Proteins. Mechanics of Polysaccharides. Mechanics and Interactions in DNA and RNA.Mechanics of Synthetic Polymers. Interplays between Chemistry and Mechanics in Single Molecules. Manipulation, Repositioning, and Targeted Delivery of Single Molecules on Substrates: Molecular Construction: Pushing, Moving, Stretching, and Connecting Individual Molecules. Extracting Molecules from Surfaces. Single Molecule Delivery by Mechanochemistry. Single-Molecule Cut and Paste. Index
