Description
Book SynopsisThe versatile RNA molecule, along with its many forms and functions, is elegantly captured in this succinct undergraduate text. Molecular Biology of RNA describes how RNA is not only an intrinsic part of the 'central dogma' of molecular biology, but also plays a part in processes as diverse as the regulation of gene expression and catalysis.
Trade ReviewReview from previous edition Highly detailed, and well illustrated, ^Molecular Biology of RNA represents the first text to address exclusively the role of RNA in biological systems. * Kevin Coward in Journal of Biological Education, 2012 *
This comprehensive textbook is pitched at just the right level and explains the concepts in sufficient detail to make them come to life. * Ilan Davis in Development, 2011 *
Table of Contents1. Introduction to Molecular Biology of RNA ; 2. RNA can form versatile structures ; 3. Catalytic RNAs ; 4. The RNA-binding proteins ; 5. Pre-mRNA splicing by the spliceosome ; 6. Regulated alternative splicing ; 7. Pre-mRNA splicing defects in development and disease ; 8. Co-transcriptional pre-mRNA processing ; 9. Nucleocytoplasmic traffic of messenger RNA ; 10. Messenger RNA localization ; 11. Translation of messenger RNA ; 12. Stability and degradation of mRNA ; 13. RNA editing ; 14. The biogenesis and nucleocytoplasmic traffic of non-coding RNAs ; 15. The 'macro' RNAs: long non-coding RNAs and epigenetics ; 16. The short non-coding RNAs and gene silencing ; 17. RNA biology: future perspectives