Description
Book SynopsisAn increasing number of technologies are being used to detect minute quantities of biomolecules and cells. However, it can be difficult to determine which technologies show the most promise for high-sensitivity and low-limit detection in different applications.
Microfluidics and Nanotechnology: Biosensing to the Single Molecule Limit details proven approaches for the detection of single cells and even single moleculesapproaches employed by the world's foremost microfluidics and nanotechnology laboratories. While similar books concentrate only on microfluidics or nanotechnology, this book focuses on the combination of soft materials (elastomers and other polymers) with hard materials (semiconductors, metals, and glass) to form integrated detection systems for biological and chemical targets. It explores physical and chemicalas well as contact and noncontactdetection methods, using case studies to demonstrate system capabilities. Presenting a snapshot of the current state
Trade Review
The book Microfluidics and Nanotechnology: Biosensing to the Single Molecule Limit, edited by Eric Lagally, offers a unique collection of detection technologies and fluidic strategies that provides inspiration for improved integration of such fields. This text provides a timely comparison of complementary advancements in biosensors and microfluidics, with state-ofthe- art developments reviewed by renowned experts.
This book represents an important contribution to the fields of microfluidics, biosensing, and single-cell analysis. The level of detail is appropriate for scientists and PhD students interested in using microfluidics for biosensing or cellular applications—perhaps in the format of a special-topics graduate course. Due to its unique yet complementary arrangement, the text provides an important perspective to all readers, but particularly for those interested in developing a new program. In this way, this book can serve as an inspiration piece for more junior scientists thinking of starting their own research group.
With its creative combination of complementary detection and fluidic technologies, this book should prove to be a timely resource for scientists looking to make an impact in biological research using novel tools such as those described within its pages.
—Springer-Verlag GmbH Germany, part of Springer Nature 2018
Table of ContentsToward Unsupervised Smart Chemical Sensor Arrays. Active CMOS Biochip for Electrochemical DNA Assays. Label-Free DNA Sensor Based on a Surface Long-Period Grating. Measuring the Physical Properties of Cells. Technologies for Low-Cost, Hall Effect-Based Magnetic Immunosensors. Two-Dimensional Paper Networks for Automated Multistep Processes in Point-of-Care Diagnostics. Droplet-Based Digital Microfluidics for Single-Cell Genetic Analysis. Droplet-Based Microfluidics for Biological Sample Preparation and Analysis. A Review of Tubeless Microfluidic Devices.
