Description
Book SynopsisThis book pursues possible strategies for synthesising mainly organic compounds, particularly those of interest to the health sector and related industries. Topics covered include addition reactions of aldehydes and ketones; the use of organometallic reagents to form carbon-carbon bonds (eg Grignard reagents); and radical reactions, including selectivity and chain reactions. Retrosynthetic analysis is introduced as a strategy for developing syntheses, along with biochemical pathways. Mechanism and Synthesis concludes with a Case Study on polymers, which demonstrates how chain reactions can be used to build up useful materials with specific properties, such as contact lenses. The Molecular World series provides an integrated introduction to all branches of chemistry for both students wishing to specialise and those wishing to gain a broad understanding of chemistry and its relevance to the everyday world and to other areas of science. The books, with their Case Studies and accompanying
Trade ReviewVery stimulating......Excellent support materials for most undergraduate chemistry courses. * Physical Sciences Educational Reviews, Volume 6, Issue 2 (David Ruddick) *
"... contains some nice enrichment material not often found in standard works." * CHOICE, May 2003 *
"I recommend this well-presented text for independent learning." * Education in Chemistry, September 2003 *
"... suitable for use as supplementary reading material for first-year undergraduates ... impressive ... The use of color illustrations throughout the text is very eye-catching ... I am happy to recommend this book to libraries ..." * The Chemical Educator, Vol 8, No 5, 2003, p 343-344 *
Table of ContentsPart 1 Carbonyl Compounds; Carbonyl Compounds in Context; The Structure of the Carbonyl Group; Nucleophilic Attack at the Carbonyl Group; Conclusion; Part 2 Synthetic Applications of Organometallic Compounds; Organomagnesium Halides; Organolithium and Organosodium Compounds; Organocopper Compounds; Review of the Reactivities of Organometallic Reagents; Organoboron Compounds; Part 3 Radical Reactions in Organic Synthesis; Reactions of Radicals; Radical-Radical Coupling Reactions (Radical Combinations); Radical Chain Reactions; Radical Fragmentation Reactions; An Application; Part 4 Strategy and Methodology in Organic Synthesis; Synthesis in Organic Chemistry; Requirements for Synthesis; Planning a Synthesis; Simple Disconnections: C-X Bonds; Simple Disconnections: C-C Bonds; CD-ROM Activity; Control in Synthesis; Further Factors Affecting the Choice of a Synthetic Route; Synthesis of a Drug; Part 5 Synthesis and Biosynthesis: Terpenes and Steroids; The Laboratory Synthesis of Monoterpenes; A Biochemical Interlude; The Synthesis of Terpenes in Living Systems; The Chemistry of Terpene Biosynthesis; From Triterpenes to Steroids; Case Study: Polymer Chemistry.
