Description
Book SynopsisThis text is intended as a practical guide for physicians and surgeons who treat diseases of the breast, both benign and malignant. Thus, general surgeons, internists, family practitioners, gynecologists, surgical oncologists, radiation oncologists, and medical oncologists will find this book useful. The management of breast diseases requires a multidisciplinary approach, and this textbook therefore includes the views of a wide range of specialists from throughout the world. Today the treatment of breast diseases is largely predicated on the results of randomized prospective trials. The results of many clinical trials are discussed in detail, and readers will find this book to be a useful guide to the evidence-based treatment of breast diseases.
The revised edition provides a comprehensive update of the previous version of the book. Specifically, it contains 2 new chapters: “Molecular Classification of Breast Cancer” and “Breast Cancer Molecular Testing for Prognosis and Prediction”. In addition, since publication of the previous edition, the results of numerous adjuvant systemic therapy and neo-adjuvant systemic therapy trials have been published, and this edition provides a comprehensive overview of these trials and discusses how they have changed the management of breast cancer. Similarly, there have been, in the last few years, important new developments in the local therapy of breast cancer. This edition discusses these new developments and particularly recent developments and controversies concerning the management of the axilla in patients with primary breast cancer. New guidelines with respect to radiotherapy are also reviewed and discussed. Finally, all chapters in the book are thoroughly revised and updated to provide readers with current understanding of the biology and treatment of breast cancer.
Table of Contents1. Anatomy and Physiology of the Breast
Martha C. Johnson and Mary L. Cutler
2. Congenital and Developmental Abnormalities of the Breast
Kristin Baumann and Telja Pursche
3. Nipple Discharge
Jill R. Dietz
4. Mastalgia
Amit Goyal and Robert E. Mansel
5. Management of Common Lactation and Breastfeeding Problems
Lisa H. Amir and Verity H. Livingstone
6. Evaluation of a Breast Mass
Alastair M. Thompson and
Andrew Evans 7. Breast Cancer Epidemiology
Alicia Brunßen, Joachim Hübner, Alexander Katalinic, Maria R. Noftz and Annika Waldmann
8. Breast Cancer Screening
Ismail Jatoi
9. Breast Imaging
Anne C. Hoyt and Irene S. Tsai
10. Premalignant and Malignant Breast Pathology
Hans-Peter Sinn
11. Breast Cancer Molecular Testing for Prognosis and Prediction
Nadia Harbeck
12. Molecular Classification of Breast Cancer
Maria Vidal, Laia Paré and Aleix Prat
13. Ductal Carcinoma in Situ
Ian H. Kunkler
14. Surgical Considerations in the Management of Primary Invasive Breast Cancer
Carissia Calvo and Ismail Jatoi
15. Management of the Axilla
John R. Benson and Vassilis Pitsinis
16. Breast Reconstructive Surgery
Yash J. Avashia, Amir Tahernia, Detlev Erdmann and Michael R. Zenn
17. The Role of Radiotherapy in Breast Cancer Management
Mutlay Sayan and Ruth Heimann
18. Adjuvant Systemic Treatment for Breast Cancer: An Overview
Rachel Nirsimloo and David A. Cameron
19. Endocrine Therapy
Olivia Pagani and Rosaria Condorelli
20. Systemic Therapy
Frederik Marmé<
21. HER2-Targeted Therapy
Phuong Dinh and Martine J. Piccart
22. Inflammatory and Locally Advanced Breast Cancer
Tamer M. Fouad, Gabriel N. Hortobagyi and Naoto T. Ueno
23. Neoadjuvant Systemic Treatment (NST)
Cornelia Liedtke and
Achim Rody 24. Metastatic Breast Cancer
Berta Sousa, Joana M. Ribeiro, Domen Ribnikar and Fátima Cardoso
25. Estrogen and Breast Cancer in Postmenopausal Women: A Critical Review
Joseph Ragaz and Shayan Shakeraneh
26. Estrogen and Cardiac Events with All-Cause Mortality: A Critical Review
Joseph Ragaz and Shayan Shakeraneh
27. Breast Diseases in Males
Darryl Schuitevoerder and John T. Vetto
28. Breast Cancer in the Older Adult
Emily J. Guerard, Madhuri V. Vithala and
Hyman B. Muss 29. Breast Cancer in Younger Women
Manuela Rabaglio and Monica Castiglione
30. Psychological Support for the Breast Cancer Patient
Donna B. Greenberg
31. Management of the Patient with a Genetic Predisposition for Breast Cancer
Sarah Colonna and Amanda Gammon
32. Chemoprevention of Breast Cancer
Jack Cuzick
33. Design, Implementation, and Interpretation of Clinical Trials
Carol K. Redmond and Jong-Hyeon Jeong
34. Structure of Breast Centers
David P. Winchester
