Description
Book SynopsisLymphedema: Complete Surgical and Medical Management is one of the first books to cover the state of the field, encompassing both surgical and nonsurgical treatments. It is divided into several areas:
- Anatomy, Physiology, and Lymphangiogenesis
- Pathophysiology and Clinical Presentation
- Diagnosis
- Treatment - including surgical and pharmacologic therapy
- Research and Future Directions
The book opens with chapters on anatomy and embryology, discusses the physiology of the lymphatic system, and examines the pathophysiology of primary and secondary lymphedema. It also reviews risk factors in breast cancer, examines lymphedema in pediatrics, and explores sentinel node biopsy. In addition, the book describes psychological and dermatological implications.
Building on this foundation, the text discusses diagnostic modalities, biomarkers, and differential lymph node mapping and clinical staging. It includes the history of lymphedema treatment and an overview of various past and present treatments in India and China, then explores pharmacological options, excisional approaches, liposuction, and venous implantation methods. Detailed presentations of lymphatic grafts and surgical treatments round out the coverage.
The book closes with a discussion on animal models, improving patient outcomes, and the potential use of stem cells in lymphedema management. Using a consistent format throughout, the book includes more than 500 illustrations, many in color. A DVD with practical surgical videos is included. With US, European, and Asian-Pacific contributing experts, this book presents a truly global approach.
Table of ContentsPart I Current Concepts in Lymphedema
1 Lymphedema: Lack of Solutions to a Clinical Problem
2 Lymphedema and Its Impact on Quality of Life
3 Quality of Life Measurement Instruments
Part II Anatomy, Physiology, and Lymphangiogenesis
4 Embryology
5 Changing Concepts in Lymphatic Pathways
6 Applied Anatomy
7 Lymphangiogenesis
8 Impact of Genetics on Lymphangiogenesis
9 Relationship Between Fat Tissue and Lymphangiogenesis
10 Lymphatic Malformations
11 Immune Regulation by the Peripheral Lymphatics
Part III Pathophysiology and Clinical Presentation
12 Pathophysiology of Primary Lymphedema
13 Pathophysiology of Secondary Lymphedema
14 Dermatologic Implications of Secondary Lymphedema of the Lower Leg
15 Filaria
16 Lymphedema in Pediatric Patients
17 Combined Lymphatic and Venous Failure: Phlebolymphedema
18 Lymphedema Risk Factors in Breast Cancer
19 Sentinel Lymph Node Biopsy Outcomes
Part IV Diagnosis of Lymphedema
20 Causes and Classification of Lymphatic Disorders
21 Basic Approaches to the Diagnosis of Lymphedema: Clinicians' Perspective
22 Biomarkers
23 Clinical Staging of Lymphedema
24 Measuring Methods
25 Hydromechanics of Intercellular Fluid and Lymph
26 Radionuclide Lymphoscintigraphy
27 Indocyanine Green Lymphography
28 Magnetic Resonance Lymphangiography
Part V Current Treatment of Lymphedema
29 Conservative Treatments for Lymphedema
30 Pharmacologic Treatment of Lymphedema
31 Excisional Approaches for the Treatment of Lymphedema
32 Liposuction
33 Multiple Lymphaticovenous Anastomoses and Multiple Lymphatic-Venous-Lymphatic Anastomoses
34 Lymphatic Grafts
35 Lymphaticovenular Anastomosis
36 Vascularized Lymph Node Transfer
37 Reverse Lymphatic Mapping
38 Local Flaps and Vascularized Lymph Node Transfer
39 Transverse Myocutaneous Gracilis With Vascularized Lymph Node Transfer
40 Lymphatic Microsurgical Preventing Healing Approach Concept
41 Combined Surgical Treatment for Breast Cancer–Related Lymphedema
42 Interventional Timing
43 Lymphedema Complications and Their Treatment
44 Treatment of Lymphedema in India
45 Surgical Treatment in China
Part VI Research and Future Directions
46 Animal Models of Lymphedema
47 Harnessing Stem Cell–Mediated Lymphangiogenesis for the Treatment of Lymphedema
48 Establishment of a Lymphedema Framework
