Description
Book SynopsisThoroughly updated with 50% new material, this introductory textbook covers the basic principles and latest research on the causes, growth, detection, and treatment of cancers. Student learning is supported with a stepwise presentation, 'Pause and Recap' boxes, end-of-chapter review questions, and additional online resources.
Trade Review'A comprehensive, engagingly written, accurate overview of a topic that has continued to rapidly evolve in recent years. As our knowledge of cancer's molecular underpinnings advances, it is essential to remain up-to-date and this book delivers. Each chapter is full of concise explanations and wonderful illustrations that convey complex concepts in a straightforward way. I highly recommend this valuable resource to all students of biology and medicine.' Andrew Lam, M.D., University of Massachusetts Medical School
'The new edition of Introduction to Cancer Biology has been well worth waiting for. It develops logically from the previous edition and brings our current understanding of all aspects of the nature of cancer biology up to date. Central to the book are chapters dealing with DNA, oncogenes, tumour suppressor genes and signalling pathways. The chapters convey the historical development of these ideas into our current understanding. Thus, the book is suitable for students, undergraduates and postgraduates with an interest or need, to develop an overview of cancer research.' Tony Bradshaw, Oxford Brookes University
'This textbook has easy to understand figures and clearly laid out chapters. My favourite is the logical roadmap describing how one should teach using this textbook. I never saw that before. I think the students will appreciate the 'pause and recap' throughout the book; what a great way to check your knowledge one step at a time.' Luiza Nogaj, Mount Saint Mary's University Los Angeles
'A comprehensive look at cancer biology and treatment with chemical-level precision.' John Schmidt, Villanova University, Pennsylvania
Table of ContentsPreface; 1. Lessons from epidemiology; 2. Causes of cancer; 3. Genetic analysis of cancer; 4. Signaling in normal cells; 5. 'Cancer genes': Mutations and cancer development; 6. What is a tumour? 7. Cancer signaling networks; 8. Cancer detection, diagnosis and radiotherapy; 9. Cancer chemotherapy; 10. The future of cancer detection and treatment; Appendix A: Tumour grading and staging; Appendix B: Classes of major oncoproteins; Appendix C: Major tumour suppressor genes; Appendix D: Ten major cancers at a glance; Glossary, References, Index.
