Description

Book Synopsis

This handbook provides an in-depth review of information across the developmental spectrum of gene and cell therapy products. From introductory information to state-of-the-art technologies and concepts, the book provides insights into upstream processes such as vector design and construction, purification, formulation and fill/finish, as well as delivery options. Planning steps for compliance with current good manufacturing practice (cGMP) to readiness for chemistry, manufacturing and controls (CMC) are also discussed. This book wraps up with examples of successes and pitfalls addressed by experts who have navigated the multiple challenges that are part of any innovative endeavor.

Features

  • Provides the most up-to-date information on the development of gene therapy, from the technology involved to gene correction and genome editing
  • Discusses siRNA, mRNA, and plasmid manufacturing
  • Describes the importance of supplier-sponsor synergies on the path to commercialization
  • Written for a diverse audience with a large number of individuals in the core technologies and supportive practices

It is intended as a one-stop resource for the availability of state-of-the-art information related to cell and gene therapy products for researchers, scientists, management and other academic and research institutions.

Handbook of Cell and Gene Therapy

    Product form

    A Paperback by Hazel Aranha

    £57.80

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    RRP £68.00 – you save £10.20 (15%)

    Order before 4pm today for delivery by Thu 27 Aug 2026.

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      Book details

      Publisher CRC Press
      Published 10 September 2024
      ISBN-13 9781032257983
      978-1032257983
      ISBN-10 1032257989
      Also in:
      Medical research

      Description

      Book Synopsis

      This handbook provides an in-depth review of information across the developmental spectrum of gene and cell therapy products. From introductory information to state-of-the-art technologies and concepts, the book provides insights into upstream processes such as vector design and construction, purification, formulation and fill/finish, as well as delivery options. Planning steps for compliance with current good manufacturing practice (cGMP) to readiness for chemistry, manufacturing and controls (CMC) are also discussed. This book wraps up with examples of successes and pitfalls addressed by experts who have navigated the multiple challenges that are part of any innovative endeavor.

      Features

      • Provides the most up-to-date information on the development of gene therapy, from the technology involved to gene correction and genome editing
      • Discusses siRNA, mRNA, and plasmid manufacturing
      • Describes the importance of supplier-sponsor synergies on the path to commercialization
      • Written for a diverse audience with a large number of individuals in the core technologies and supportive practices

      It is intended as a one-stop resource for the availability of state-of-the-art information related to cell and gene therapy products for researchers, scientists, management and other academic and research institutions.

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