Description

Book Synopsis

This fully revised third edition includes up-to-date topics and developments in the field, which has made tremendous strides since the publication of the second edition in 2004. Many novel techniques based on Next Generation Sequencing have sped up the analysis of fungi and major advances have been made in genome editing, leading to a deeper understanding of the genetics underlying cellular processes as well as their applicability. At the same time, the relevance of fungi is unbroken, both due to the serious threats to human health and welfare posed by fungal pests and pathogens, and to the many benefits that fungal biotechnology can offer for diverse emerging markets and processes that form the basis of the modern bioeconomy.

With regard to these advances, the first section of this volume, Genetics, illustrates the basic genetic processes underlying inheritance, cell biology, metabolism and “lifestyles” of fungi. The second section, Biotechnology, addresses the applied side of fungal genetics, ranging from new tools for synthetic biology to the biotechnological potential of fungi from diverse environments. Gathering chapters written by reputed scientists, the book represents an invaluable reference guide for fungal biologists, geneticists and biotechnologists alike.




Trade Review
“In such a rapidly moving area of mycology, it is not surprising that there is much new to report 16 years on. While badged as a third edition, it is more a collection of in-depth review articles, many on topics which have largely emerged in the years since the second. … a particularly valuable synopsis of the current state of fungal genomics. … and an especially exciting overview of the potential of anaerobic gut fungi.” (IMA Fungus, December 31, 2021)

Table of Contents

Molecular Genetics

1 Chromatin Structure and Function in Neurospora crassa

A.J. Courtney, A.R. Ferraro, A.D. Klocko, Z. LEWIS (U. of Georgia, USA)

zlewis@uga.edu

2 Origin, function and transmission of accessory chromosomes

M. HABIG and E. HOLTGREWE STUKENBROCK (MPI für Evolutionsbiologie, D)

estukenbrock@bot.uni-kiel.de

3 Genetics of the unfolded protein response in fungi

R. Harting and K. HEIMEL (Uni Göttingen, D)

kheimel@gwdg.de

4 From genetics to molecular oscillations: the circadian clock in Neurospora crassa

M.S. JANKOWSKI, Z.A. CHASE and J.M. HURLEY (Rensselaer Polytech, USA)

hurlej2@rpi.edu

5 small RNAs in fungi

F.E. Nicolás, L. Murcia, E. Navarro, J.T. Cánovas-Márquez, V. Garre (Univ. de Murcia, Spain)

vgarre@um.es

6 NLR function in fungi as revealed by the study of self/non-self recognition systems

A. DASKALOV, W. DYRKA and S. SAUPE (CNRS, Bordeaux, F)

sven.saupe@ibgc.cnrs.fr

7 Genetics and genomics decipher partner biology in arbuscular mycorrhizas

L. Lanfranco, G. Carotenuto, A. Genre, P. Bonfante (Torino, Italy)

paola.bonfante@unito.it

8 Coordination of fungal secondary metabolism and development

J. GERKE, A.M. KÖHLER, C. MEISTER, K.G. THIEME, H. AMOEDO, G.H. BRAUS (Göttingen, D)

gbraus@gwdg.de

9 Fungal Genomics

R. OHM (Utrecht, NL)

r.a.ohm@uu.nl

Biotechnology

10 Filamentous fungi as hosts for heterologous production of proteins and secondary metabolites in the post-genomic era

J.K. Rendsvig, M.E. Futyma, Z.D. Jarczynska, U. H. MORTENSEN (DTU, Denmark)

um@bio.dtu.dk

11 New Avenues towards drug discovery in fungi

M. Flak, M.K.C. Krespach, A.J. Pschibul, V. Schroeckh, A.A. Brakhage (Jena, D)

axel.brakhage@uni-jena.de

12 Exploiting fungal photobiology as a source of novel bio-blocks for optogenetic systems

V. Rojas, F. Salinas, L. Guzman-Zamora, A. Romero, V. Delgado and L.F. LARRONDO (PUC, Chile)

llarrondo@bio.puc.cl

13 Yeast cell factories

B. Schmelzer, M. Altvater, B. Gasser, M. Sauer, D. MATTANOVICH (BOKU, Vienna, AUT)

diethard.mattanovich@boku.ac.at

14 Engineering Saccharomyces cerevisiae for production of fatty acids and their derivatives

L. Baumann, F. Wernig, S. Henritzi, M. OREB (Frankfurt)

M.Oreb@bio.uni-frankfurt.de

15 Fungi Involved in the Biodeterioration and Bioconversion of Lignocellulose Substrates

B. GOODELL (UMass)

bgoodell@umass.edu

16 Biotechnology of marine fungi: New workhorses and new uses - using marine fungal diversity as a source for biotechnology

A. Kramer, A. LABES (HS Flensburg, D)

antje.labes@hs-flensburg.de

17 The biotechnological potential of anaerobic gut fungi

V. Dollhofer, D. Young, S. Seppälä, C. Hooker, N. Youssef, S.M. Podmirseg, M. Nagler, M. Reilly, Y. Li, K. Fliegerová, Y. Cheng, G. W. Griffith, M. Elshahed, K.V. Solomon, M.A. O’Malley, M.K. Theodorou (LFL Bayern)

Veronika.Dollhofer@lfl.bayern.de

Genetics and Biotechnology

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    A Hardback by J. Philipp Benz, Kerstin Schipper

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      View other formats and editions of Genetics and Biotechnology by J. Philipp Benz

      Publisher: Springer Nature Switzerland AG
      Publication Date: 29/10/2020
      ISBN13: 9783030499235, 978-3030499235
      ISBN10: 3030499235

      Description

      Book Synopsis

      This fully revised third edition includes up-to-date topics and developments in the field, which has made tremendous strides since the publication of the second edition in 2004. Many novel techniques based on Next Generation Sequencing have sped up the analysis of fungi and major advances have been made in genome editing, leading to a deeper understanding of the genetics underlying cellular processes as well as their applicability. At the same time, the relevance of fungi is unbroken, both due to the serious threats to human health and welfare posed by fungal pests and pathogens, and to the many benefits that fungal biotechnology can offer for diverse emerging markets and processes that form the basis of the modern bioeconomy.

      With regard to these advances, the first section of this volume, Genetics, illustrates the basic genetic processes underlying inheritance, cell biology, metabolism and “lifestyles” of fungi. The second section, Biotechnology, addresses the applied side of fungal genetics, ranging from new tools for synthetic biology to the biotechnological potential of fungi from diverse environments. Gathering chapters written by reputed scientists, the book represents an invaluable reference guide for fungal biologists, geneticists and biotechnologists alike.




      Trade Review
      “In such a rapidly moving area of mycology, it is not surprising that there is much new to report 16 years on. While badged as a third edition, it is more a collection of in-depth review articles, many on topics which have largely emerged in the years since the second. … a particularly valuable synopsis of the current state of fungal genomics. … and an especially exciting overview of the potential of anaerobic gut fungi.” (IMA Fungus, December 31, 2021)

      Table of Contents

      Molecular Genetics

      1 Chromatin Structure and Function in Neurospora crassa

      A.J. Courtney, A.R. Ferraro, A.D. Klocko, Z. LEWIS (U. of Georgia, USA)

      zlewis@uga.edu

      2 Origin, function and transmission of accessory chromosomes

      M. HABIG and E. HOLTGREWE STUKENBROCK (MPI für Evolutionsbiologie, D)

      estukenbrock@bot.uni-kiel.de

      3 Genetics of the unfolded protein response in fungi

      R. Harting and K. HEIMEL (Uni Göttingen, D)

      kheimel@gwdg.de

      4 From genetics to molecular oscillations: the circadian clock in Neurospora crassa

      M.S. JANKOWSKI, Z.A. CHASE and J.M. HURLEY (Rensselaer Polytech, USA)

      hurlej2@rpi.edu

      5 small RNAs in fungi

      F.E. Nicolás, L. Murcia, E. Navarro, J.T. Cánovas-Márquez, V. Garre (Univ. de Murcia, Spain)

      vgarre@um.es

      6 NLR function in fungi as revealed by the study of self/non-self recognition systems

      A. DASKALOV, W. DYRKA and S. SAUPE (CNRS, Bordeaux, F)

      sven.saupe@ibgc.cnrs.fr

      7 Genetics and genomics decipher partner biology in arbuscular mycorrhizas

      L. Lanfranco, G. Carotenuto, A. Genre, P. Bonfante (Torino, Italy)

      paola.bonfante@unito.it

      8 Coordination of fungal secondary metabolism and development

      J. GERKE, A.M. KÖHLER, C. MEISTER, K.G. THIEME, H. AMOEDO, G.H. BRAUS (Göttingen, D)

      gbraus@gwdg.de

      9 Fungal Genomics

      R. OHM (Utrecht, NL)

      r.a.ohm@uu.nl

      Biotechnology

      10 Filamentous fungi as hosts for heterologous production of proteins and secondary metabolites in the post-genomic era

      J.K. Rendsvig, M.E. Futyma, Z.D. Jarczynska, U. H. MORTENSEN (DTU, Denmark)

      um@bio.dtu.dk

      11 New Avenues towards drug discovery in fungi

      M. Flak, M.K.C. Krespach, A.J. Pschibul, V. Schroeckh, A.A. Brakhage (Jena, D)

      axel.brakhage@uni-jena.de

      12 Exploiting fungal photobiology as a source of novel bio-blocks for optogenetic systems

      V. Rojas, F. Salinas, L. Guzman-Zamora, A. Romero, V. Delgado and L.F. LARRONDO (PUC, Chile)

      llarrondo@bio.puc.cl

      13 Yeast cell factories

      B. Schmelzer, M. Altvater, B. Gasser, M. Sauer, D. MATTANOVICH (BOKU, Vienna, AUT)

      diethard.mattanovich@boku.ac.at

      14 Engineering Saccharomyces cerevisiae for production of fatty acids and their derivatives

      L. Baumann, F. Wernig, S. Henritzi, M. OREB (Frankfurt)

      M.Oreb@bio.uni-frankfurt.de

      15 Fungi Involved in the Biodeterioration and Bioconversion of Lignocellulose Substrates

      B. GOODELL (UMass)

      bgoodell@umass.edu

      16 Biotechnology of marine fungi: New workhorses and new uses - using marine fungal diversity as a source for biotechnology

      A. Kramer, A. LABES (HS Flensburg, D)

      antje.labes@hs-flensburg.de

      17 The biotechnological potential of anaerobic gut fungi

      V. Dollhofer, D. Young, S. Seppälä, C. Hooker, N. Youssef, S.M. Podmirseg, M. Nagler, M. Reilly, Y. Li, K. Fliegerová, Y. Cheng, G. W. Griffith, M. Elshahed, K.V. Solomon, M.A. O’Malley, M.K. Theodorou (LFL Bayern)

      Veronika.Dollhofer@lfl.bayern.de

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