Description

Book Synopsis


Table of Contents

Contributors xix

Preface xxv

Acknowledgements xxvii

How to use your textbook xxix

About the companion website xxxi

Chapter 1 The critical care unit 1
Vikki Park

Introduction 2

Levels of care 2

The critical care environment 2

Critical care patients 3

Level 1 care 4

Level 2 care 4

Level 3 care 4

Critical care competence 5

The interprofessional team 6

Communication 7

Ways of working 7

Understanding philosophies of care 8

Humanising critical care 8

Surviving critical care 9

Death in critical care 9

Resilience 9

Nursing considerations and recommendations for practice 11

Future challenges 11

Conclusion 11

References 12

Chapter 2 Organisational influences 14
Vikki Park

Introduction 15

The four UK nations 15

Legislation 15

Professional Statutory Regulatory Bodies (PSRBs) 15

Shared decision making 16

Capacity for shared decision making 16

Confidentiality 17

Decisions relating to end-of-life care 17

Risk management 18

International influences 18

National influences 18

UK government organisations 18

Networks 19

National guidelines 20

Quality assurance 20

Local policies 21

Nursing considerations and recommendations for practice 21

Conclusion 21

References 22

Chapter 3 Legal and ethical issues 24
Leonie Armstrong, Tracey Carrott, and Jacqueline Newby

Introduction 25

Confidentiality 25

End-of-life care and best interest decisions 26

Ethical themes 27

Mental Capacity Act 27

Organ donation 29

Consent (authorisation in Scotland) for organ donation 30

First person consent 31

First person opt-in 31

First person opt-out 31

Appointed/nominated representative (not Scotland) 31

Deemed consent 31

The ethics of deemed consent 32

Consent from a person in the highest-ranking relationship 32

Cadaveric organ donation 33

The organ donation process 33

Post organ retrieval 34

Organ allocation 34

Conclusion 35

References 35

Chapter 4 Professional issues in critical care 37
Aurora Medonica

Introduction 38

Opportunities for learning 38

NMC Code in critical care units: journey to independent, safe practice 38

The core principles 39

UK National Competency Framework: critical care 41

Development of critical thinking in healthcare 42

The prioritising process 42

Support systems: the student 44

Conclusion 44

References 45

Chapter 5 Using an evidence-based approach 46
Sadie Diamond-Fox and Alexandra Gatehouse Introduction 47

What is evidence-based practice (EBP)? 47

Step 1: formulating a clinical question – the PICO method 48

Step 2: locating the evidence/research: performing a systematic literature review 48

Step 3: critical appraisal and the hierarchy of evidence 49

Step 4: extracting the most relevant and useful results 51

Step 5: implementing research into practice 52

Quality healthcare in critical care 53

Clinical audit and quality improvement 53

Research and development in critical care 55

Conclusion 56

References 56

Chapter 6 Nursing care 58
Sarah Crowe and Fiona McLeod

Introduction 59

Standards of care 59

Physical care 63

Mobility 66

Critical care bundles 67

Conclusion 67

References 68

Chapter 7 Skin integrity 70
Victoria Clemett

Introduction 71

Anatomy and physiology of the skin 71

Impact of ageing on skin and tissue integrity 71

Pressure ulcers 71

Nursing assessment 75

Prevention of pressure ulcers 76

Management of pressure ulcers 79

Wound healing 79

Patient factors that affect wound healing 79

Nursing assessment 79

Recognising wound infection 81

Management of non-healing wounds 83

Conclusion 83

References 84

Chapter 8 Shock 86
Barry Hill

Introduction 87

Shock 87

Hypovolaemic shock 87

Blood analysis 88

Multiple organ dysfunction syndrome 89

Staging of hypovolaemic shock 89

Principles of managing hypovolaemic shock 90

Fluid resuscitation 91

Training and education for Registered Nurses 91

Cardiogenic shock 91

Obstructive shock 93

Altered pathophysiology 93

Tension pneumothorax 94

Cardiac tamponade 94

Pulmonary embolism (PE) 94

Distributive shock 95

Conclusion 96

References 97

Chapter 9 Communication 98
Paul Jebb

Introduction 99

Communicating effectively with patients 100

Communicating during a pandemic 100

Communication with families 102

Conclusion 103

References 103

Chapter 10 Electronic health records 105
Timothy Kuhn

Introduction 106

Digitisation within healthcare 106

Understand your responsibilities and the law in relation to record keeping 107

Intensive Care Society Guidelines 107

Understanding the different types of EHRs in critical care and how they are used 108

Understanding what patient data is available within the critical care unit and how this is recorded in an electronic health record 109

Understanding how EHRs are used in critical care audit and research 110

Understanding the benefits and barriers to EHRs 112

Conclusion 113

References 113

Chapter 11 Pharmacology 115
Sadie Diamond-Fox and Alexandra Gatehouse

Introduction 116

Principles of pharmacology and pharmacotherapy 116

The processes of drug therapy 116

Medication safety in critical care 119

Drugs and dialysis 120

Core drugs utilised within critical care 120

Respiratory drugs 120

Cardiovascular drugs 122

Haematological drugs 126

Renal drugs 126

Fluids and electrolytes 127

Gastrointestinal drugs 128

Insulin 129

H2-histamine antagonists and proton pump inhibitors (PPIs) 129

Anti-emetics 129

Laxatives and anti-diarrhoeal drugs 130

Neurological drugs 130

Analgesics 130

Opioids 130

Non-opioid analgesics 130

Epidural and regional anaesthesia 130

Sedatives and anxiolytics 131

Muscle relaxants 131

Anticonvulsants 132

Antideliriogenics 132

Immunomodulatory drugs 132

Antibacterial agents 132

Antifungals 133

Antiviral drugs 134

Corticosteroids 134

Immunoglobulins 134

Toxicology 134

Conclusion 135

References 135

Chapter 12 Anaesthesia and sedation 138
Lorraine Mutrie and Iain Carstairs

Introduction 139

Indications for sedation and anaesthesia 139

Anaesthetic and sedative medications 142

Sedative drugs 142

Neuromuscular blocking agents and reversal agents 143

Sedation management 145

Conclusion 147

References 148

Chapter 13 Medicines management and drug calculations 150
Jan Guerin

Introduction 151

Purpose of pharmacological interventions in the critically ill adult patient 152

Legal and professional issues 152

Collaborative multidisciplinary team working 154

Medication errors 154

Overview of routes and methods of administering medications in CCU 155

Rights of medication administration 158

Managing and reporting a medication error 159

Anaphylaxis 160

Pathophysiology and clinical manifestations of DIA 160

Management for DIA 160

Medication calculation formulae 160

Displacement 165

Conclusion 165

References 166

Chapter 14 Neurological critical care 167
Samantha O’Driscoll

Introduction 168

Neurological anatomy and physiology 168

Central nervous system 169

Neurological assessment 174

Signs and symptoms of increasing ICP 179

Primary and secondary brain injury 180

Management of raised ICP 180

Nursing care 181

Transfer 182

Conclusion 184

References 184

Chapter 15 Cognition 186
Barry Hill and Sadie Diamond-Fox

Introduction 187

Cognitive impairment 187

Causes of cognitive impairment 187

Signs of cognitive impairment 188

Delirium 188

Risk factors 190

Management of delirium 191

Sleep 193

Assessment of sleep in ICU 193

Conclusion 195

References 195

Chapter 16 Respiratory care: intubation and mechanical ventilation 197
Barry Hill and Lorraine Mutrie

Introduction 198

Respiratory failure 198

Hypoventilation 198

Ventilation/perfusion (V/Q) mismatch 199

Work of breathing 199

Arterial blood gases (ABGs) 200

Non-invasive

ventilation (NIV) 201

Continuous positive airway pressure (CPAP) 204

High flow nasal oxygen 204

Intubation 204

Mechanical ventilation 206

Artificial ventilation 207

Minute ventilation (Vm) 207

Fraction of inspired oxygen 207

Positive end-expiratory

pressure (PEEP) 207

Volume control 207

Pressure control 207

Inspiratory:Expiratory (I:E) ratio 208

Inverse ratio 208

Synchronisation 208

Humidification 208

Benefits of mechanical ventilation 208

Risks of mechanical ventilation 208

Ventilator care bundles 209

Prone positioning 209

Prone positioning in COVID-19 209

Weaning from mechanical ventilation 210

Conclusion 210

References 211

Chapter 17 Lung function in critical care 213
Rana Din and Joyce Smith

Introduction 214

Anatomy and physiology 214

Composition of air 215

Alveolar gas 215

Expired air 216

Lung volumes 216

Pulmonary ventilation 216

External respiration 217

Ventilation/Perfusion 217

Transport of gases 217

Internal respiration 218

Assessment of lung function 220

Normal breath sounds (vesicular) 221

Absent Sounds 221

Wheeze 222

Crackles 222

The work of breathing 222

Compliance 222

Resistance 222

Emphysema 222

Asthma 223

Obstructive sleep apnoea 224

Prone positioning 224

Conclusion 225

References 226

Chapter 18 Cardiac physiology 227
Paul Sinnott

Introduction 228

Functions of the cardiovascular system 228

Anatomy of the heart and great vessels 228

Pericardium 229

Layers of the heart 229

Chambers of the heart 230

Valves of the heart 230

Coronary circulation 232

Cardiac conduction system 235

The cardiac cycle 236

Cardiac output and blood pressure 237

Regulation of heart rate 238

Stroke volume 239

The regulation of blood pressure 240

The microcirculation 242

Capillary exchange 243

Effects of ventilation on the cardiovascular system 245

Conclusion 245

References 246

Chapter 19 Cardiovascular critical care 247
Alice Shaw and Paul Sinnott

Introduction 248

Cardiovascular assessment 248

Heart rate and rhythm 248

Atrial ectopic beats 249

Ventricular ectopic beats 253

Blood pressure 254

Invasive blood pressure monitoring 255

Central venous catheters (CVCs) and central venous pressure (CVP) 256

Markers of organ and tissue perfusion 258

Neurological status 258

Urine output 258

Blood results 259

Advanced haemodynamic monitoring 260

Cardiac pacing 262

Nursing considerations and recommendations for practice 263

Conclusion 263

References 263

Chapter 20 Fluids and electrolytes in critically ill patients 265
Barry Hill

Introduction 266

The role of the critical care nurse 266

Intravenous fluids 266

Crystalloids versus colloids critical care 267

Fluid management 268

Third spacing 269

Assessment and monitoring 269

Training and education 271

Electrolyte replacement therapy 271

Management of hyperkalaemia 272

Oral sodium and water 272

Oral rehydration therapy (ORT) 272

Oral bicarbonate 273

Parenteral preparations for fluid and electrolyte imbalance 273

Plasma and plasma substitutes 276

Plasma substitutes 276

Fluid overload 276

The four Ds of fluid management 276

Hyponatraemia 277

Hypernatraemia 277

Hypokalaemia 277

Hyperkalaemia 277

Hypophosphataemia 278

Hypocalcaemia 278

Hypomagnesaemia 278

Conclusion 279

References 279

Chapter 21 Critical care emergencies 280
Alexandra Gatehouse and Sadie Diamond-Fox

Introduction 281

A – Airway 282

B – Breathing 290

C – Circulation/Cardiovascular 291

D – Disability 298

E – Everything else (exposure, endocrine, electrolytes and environmental) 301

Care of the patient post return of spontaneous circulation (ROSC) 307

Critical care emergencies and human factors 307

Debriefing 309

Do-not-attempt-cardiopulmonary-resuscitation (DNACPR) and Recommended Summary Plan for Emergency Care and Treatment (ReSPECT) 309

Conclusion 310

References 310

Chapter 22 Gastrointestinal critical care 313
Anna Riley, Joe Box, and Aileen Aherne

Introduction 314

Anatomy and physiology 314

GI monitoring and investigation in the critically ill 317

Imaging and endoscopy 318

Bowel charts and abnormal GI motility 320

The acute abdomen in critical care 322

Common surgical procedures cared for in critical care 325

Post-operative monitoring 325

Abdominal surgical drains 326

Anaesthetics 326

Post-operative complications 326

Wound dehiscence 327

GI pharmacology 327

Conclusion 328

References 328

Chapter 23 Nutrition in critical care 330
Barry Hill and Lorraine Mutrie

Introduction 331

Pathophysiology 331

Fight or flight 332

Resistance 332

Exhaustion 332

Nutritional screening and assessment 333

Indirect calorimetry (IC) 333

Routes of administration 334

Nursing considerations and recommendations for practice 336

Care of people with feeding tubes 336

Glycaemic control 337

Refeeding syndrome 338

Discontinuing feed 339

Nutritional guidance 339

Conclusion 340

References 341

Chapter 24 Renal critical care 343
Alexandra Gatehouse and Sadie Diamond-Fox

Introduction 344

Anatomy and physiology of the renal tract 344

Vascular supply 344

Renin-angiotensin-aldosterone system (RASS) 344

The nephrons 345

Control of plasma osmolality 346

Electrolyte balance 346

Acid-base balance 352

Renal failure 352

Acute kidney injury 353

Classification of AKI 353

Pathophysiology 353

Organ cross-talk 354

Risk factors for AKI 355

Clinical features and examination 355

Investigations 355

Specific disorders associated with AKI 357

Drug-induced renal damage 357

Management of AKI 359

Clinical features and examination 361

Management 361

Chronic kidney disease 362

Management 362

Diabetic nephropathy 362

Continuous renal replacement therapy (CRRT) 364

Dosing of CRRT 364

Anticoagulation 364

Drug dosing and RRT 367

Kidney transplantation – critical care considerations 367

Conclusion 368

References 368

Chapter 25 Endocrine critical care 370
Geraldine Fitzgerald O’Connor and Emma Long

Introduction 371

Thyroid and parathyroid glands 371

Disorders of the thyroid gland 371

Thyroid crisis 372

Parathyroid glands 372

Disorders of the parathyroid glands 372

Hypocalcaemia 373

Pituitary gland 373

Disorders of the pituitary gland 373

Diabetes insipidus 374

Pathophysiology 375

Hyperglycaemia in the critically ill 376

Diabetic emergencies 376

Pathophysiology 380

Conclusion 383

References 384

Chapter 26 Haematological and immunological critical care 385
Barry Hill, Gerri Mortimore, and Pamela Arasen

Introduction 386

Normal physiology 386

Blood components 386

Haematopoiesis 387

Disorders of erythrocytes 387

B12 vitamin deficiency 387

Sickle cell anaemia 388

Genetic haemochromatosis 389

Haemostasis 390

Lymphoma 390

Disseminated intravascular coagulation 393

Thrombocytopenia 394

Neutropenia and sepsis 394

Vasculitis 396

Blood transfusions in adults 397

Blood sample collections 398

Blood groups 398

Compatibility 399

Indications for blood transfusions 399

Platelets 400

Fresh frozen plasma (FFP) 400

Cryoprecipitate 400

Granulocytes 400

Procedural safety 400

Pre-procedure and sampling 400

Administration of the blood product 400

Post-procedural care 401

Traceability 401

Patient information 402

Alternatives to blood transfusions 403

Summary of SaBTO recommendations on consent 403

Conclusion 408

References 408

Chapter 27 Musculoskeletal considerations in critical care 411
Clare L. Wade and Helen Sanger

Introduction 412

Trauma 412

Management of traumatic injury 413

Intensive care unit-acquired weakness 415

Assessment of musculoskeletal impairment or injury 418

Management of musculoskeletal injury and impairment 419

Conclusion 424

References 424

Chapter 28 Burn care within a critical care setting 426
Nicole Lee

Introduction 427

Classification of burn wound depths 427

Pathological considerations 429

Burn size estimation 430

An ABCDE approach to burn care 432

Breathing 433

Cardiovascular 433

Disability (neurological assessment) 434

Exposure (and everything else) 434

Psychological support 434

Acknowledgement 436

References 436

Chapter 29 Maternal critical care 438
Wendy Pollock

Introduction 439

Epidemiology 439

Adapted physiology 439

Recognising clinical deterioration 441

Nursing considerations and recommendations for practice 442

Conclusion 448

References 449

Chapter 30 Critical care transfers 451
Kirstin Geer, Mark Cannan, and Stuart Cox

Inter-hospital and intra-hospital patient transfers 452

Transfer of the critically ill adult 452

Critical care bed and repatriation 456

The risks of critical care transfer 457

Preparation for transfer 458

ABCDE process during critical care transfer 458

Conclusion 469

References 469

Chapter 31 Rehabilitation after critical illness 470
Helen Sanger and Clare L. Wade

Introduction 471

The impact of critical illness – what do we mean by morbidity? 471

Describing physical functioning and morbidity 472

Models of post-critical care morbidity 473

Assessment 473

Goals 475

Key timepoints in RaCI 477

Treatment 478

National guidelines and standards 480

Conclusion 481

References 481

Chapter 32 Dying and death 484
Helen Merlane and Leonie Armstrong

Introduction 485

End-of-life care 485

Palliative care 486

Dying 486

Recognising Dying 486

Advance care planning 488

Involve and support 489

Nursing the dying patient 489

The critical care environment 489

Symptom management 490

End-of-life care discharges from a critical care setting 491

Care after death 494

Conclusion 495

References 495

Index 497

Fundamentals of Critical Care

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      View other formats and editions of Fundamentals of Critical Care by Ian Peate

      Publisher: John Wiley and Sons Ltd
      Publication Date: 29/09/2022
      ISBN13: 9781119783251, 978-1119783251
      ISBN10: 1119783259

      Description

      Book Synopsis


      Table of Contents

      Contributors xix

      Preface xxv

      Acknowledgements xxvii

      How to use your textbook xxix

      About the companion website xxxi

      Chapter 1 The critical care unit 1
      Vikki Park

      Introduction 2

      Levels of care 2

      The critical care environment 2

      Critical care patients 3

      Level 1 care 4

      Level 2 care 4

      Level 3 care 4

      Critical care competence 5

      The interprofessional team 6

      Communication 7

      Ways of working 7

      Understanding philosophies of care 8

      Humanising critical care 8

      Surviving critical care 9

      Death in critical care 9

      Resilience 9

      Nursing considerations and recommendations for practice 11

      Future challenges 11

      Conclusion 11

      References 12

      Chapter 2 Organisational influences 14
      Vikki Park

      Introduction 15

      The four UK nations 15

      Legislation 15

      Professional Statutory Regulatory Bodies (PSRBs) 15

      Shared decision making 16

      Capacity for shared decision making 16

      Confidentiality 17

      Decisions relating to end-of-life care 17

      Risk management 18

      International influences 18

      National influences 18

      UK government organisations 18

      Networks 19

      National guidelines 20

      Quality assurance 20

      Local policies 21

      Nursing considerations and recommendations for practice 21

      Conclusion 21

      References 22

      Chapter 3 Legal and ethical issues 24
      Leonie Armstrong, Tracey Carrott, and Jacqueline Newby

      Introduction 25

      Confidentiality 25

      End-of-life care and best interest decisions 26

      Ethical themes 27

      Mental Capacity Act 27

      Organ donation 29

      Consent (authorisation in Scotland) for organ donation 30

      First person consent 31

      First person opt-in 31

      First person opt-out 31

      Appointed/nominated representative (not Scotland) 31

      Deemed consent 31

      The ethics of deemed consent 32

      Consent from a person in the highest-ranking relationship 32

      Cadaveric organ donation 33

      The organ donation process 33

      Post organ retrieval 34

      Organ allocation 34

      Conclusion 35

      References 35

      Chapter 4 Professional issues in critical care 37
      Aurora Medonica

      Introduction 38

      Opportunities for learning 38

      NMC Code in critical care units: journey to independent, safe practice 38

      The core principles 39

      UK National Competency Framework: critical care 41

      Development of critical thinking in healthcare 42

      The prioritising process 42

      Support systems: the student 44

      Conclusion 44

      References 45

      Chapter 5 Using an evidence-based approach 46
      Sadie Diamond-Fox and Alexandra Gatehouse Introduction 47

      What is evidence-based practice (EBP)? 47

      Step 1: formulating a clinical question – the PICO method 48

      Step 2: locating the evidence/research: performing a systematic literature review 48

      Step 3: critical appraisal and the hierarchy of evidence 49

      Step 4: extracting the most relevant and useful results 51

      Step 5: implementing research into practice 52

      Quality healthcare in critical care 53

      Clinical audit and quality improvement 53

      Research and development in critical care 55

      Conclusion 56

      References 56

      Chapter 6 Nursing care 58
      Sarah Crowe and Fiona McLeod

      Introduction 59

      Standards of care 59

      Physical care 63

      Mobility 66

      Critical care bundles 67

      Conclusion 67

      References 68

      Chapter 7 Skin integrity 70
      Victoria Clemett

      Introduction 71

      Anatomy and physiology of the skin 71

      Impact of ageing on skin and tissue integrity 71

      Pressure ulcers 71

      Nursing assessment 75

      Prevention of pressure ulcers 76

      Management of pressure ulcers 79

      Wound healing 79

      Patient factors that affect wound healing 79

      Nursing assessment 79

      Recognising wound infection 81

      Management of non-healing wounds 83

      Conclusion 83

      References 84

      Chapter 8 Shock 86
      Barry Hill

      Introduction 87

      Shock 87

      Hypovolaemic shock 87

      Blood analysis 88

      Multiple organ dysfunction syndrome 89

      Staging of hypovolaemic shock 89

      Principles of managing hypovolaemic shock 90

      Fluid resuscitation 91

      Training and education for Registered Nurses 91

      Cardiogenic shock 91

      Obstructive shock 93

      Altered pathophysiology 93

      Tension pneumothorax 94

      Cardiac tamponade 94

      Pulmonary embolism (PE) 94

      Distributive shock 95

      Conclusion 96

      References 97

      Chapter 9 Communication 98
      Paul Jebb

      Introduction 99

      Communicating effectively with patients 100

      Communicating during a pandemic 100

      Communication with families 102

      Conclusion 103

      References 103

      Chapter 10 Electronic health records 105
      Timothy Kuhn

      Introduction 106

      Digitisation within healthcare 106

      Understand your responsibilities and the law in relation to record keeping 107

      Intensive Care Society Guidelines 107

      Understanding the different types of EHRs in critical care and how they are used 108

      Understanding what patient data is available within the critical care unit and how this is recorded in an electronic health record 109

      Understanding how EHRs are used in critical care audit and research 110

      Understanding the benefits and barriers to EHRs 112

      Conclusion 113

      References 113

      Chapter 11 Pharmacology 115
      Sadie Diamond-Fox and Alexandra Gatehouse

      Introduction 116

      Principles of pharmacology and pharmacotherapy 116

      The processes of drug therapy 116

      Medication safety in critical care 119

      Drugs and dialysis 120

      Core drugs utilised within critical care 120

      Respiratory drugs 120

      Cardiovascular drugs 122

      Haematological drugs 126

      Renal drugs 126

      Fluids and electrolytes 127

      Gastrointestinal drugs 128

      Insulin 129

      H2-histamine antagonists and proton pump inhibitors (PPIs) 129

      Anti-emetics 129

      Laxatives and anti-diarrhoeal drugs 130

      Neurological drugs 130

      Analgesics 130

      Opioids 130

      Non-opioid analgesics 130

      Epidural and regional anaesthesia 130

      Sedatives and anxiolytics 131

      Muscle relaxants 131

      Anticonvulsants 132

      Antideliriogenics 132

      Immunomodulatory drugs 132

      Antibacterial agents 132

      Antifungals 133

      Antiviral drugs 134

      Corticosteroids 134

      Immunoglobulins 134

      Toxicology 134

      Conclusion 135

      References 135

      Chapter 12 Anaesthesia and sedation 138
      Lorraine Mutrie and Iain Carstairs

      Introduction 139

      Indications for sedation and anaesthesia 139

      Anaesthetic and sedative medications 142

      Sedative drugs 142

      Neuromuscular blocking agents and reversal agents 143

      Sedation management 145

      Conclusion 147

      References 148

      Chapter 13 Medicines management and drug calculations 150
      Jan Guerin

      Introduction 151

      Purpose of pharmacological interventions in the critically ill adult patient 152

      Legal and professional issues 152

      Collaborative multidisciplinary team working 154

      Medication errors 154

      Overview of routes and methods of administering medications in CCU 155

      Rights of medication administration 158

      Managing and reporting a medication error 159

      Anaphylaxis 160

      Pathophysiology and clinical manifestations of DIA 160

      Management for DIA 160

      Medication calculation formulae 160

      Displacement 165

      Conclusion 165

      References 166

      Chapter 14 Neurological critical care 167
      Samantha O’Driscoll

      Introduction 168

      Neurological anatomy and physiology 168

      Central nervous system 169

      Neurological assessment 174

      Signs and symptoms of increasing ICP 179

      Primary and secondary brain injury 180

      Management of raised ICP 180

      Nursing care 181

      Transfer 182

      Conclusion 184

      References 184

      Chapter 15 Cognition 186
      Barry Hill and Sadie Diamond-Fox

      Introduction 187

      Cognitive impairment 187

      Causes of cognitive impairment 187

      Signs of cognitive impairment 188

      Delirium 188

      Risk factors 190

      Management of delirium 191

      Sleep 193

      Assessment of sleep in ICU 193

      Conclusion 195

      References 195

      Chapter 16 Respiratory care: intubation and mechanical ventilation 197
      Barry Hill and Lorraine Mutrie

      Introduction 198

      Respiratory failure 198

      Hypoventilation 198

      Ventilation/perfusion (V/Q) mismatch 199

      Work of breathing 199

      Arterial blood gases (ABGs) 200

      Non-invasive

      ventilation (NIV) 201

      Continuous positive airway pressure (CPAP) 204

      High flow nasal oxygen 204

      Intubation 204

      Mechanical ventilation 206

      Artificial ventilation 207

      Minute ventilation (Vm) 207

      Fraction of inspired oxygen 207

      Positive end-expiratory

      pressure (PEEP) 207

      Volume control 207

      Pressure control 207

      Inspiratory:Expiratory (I:E) ratio 208

      Inverse ratio 208

      Synchronisation 208

      Humidification 208

      Benefits of mechanical ventilation 208

      Risks of mechanical ventilation 208

      Ventilator care bundles 209

      Prone positioning 209

      Prone positioning in COVID-19 209

      Weaning from mechanical ventilation 210

      Conclusion 210

      References 211

      Chapter 17 Lung function in critical care 213
      Rana Din and Joyce Smith

      Introduction 214

      Anatomy and physiology 214

      Composition of air 215

      Alveolar gas 215

      Expired air 216

      Lung volumes 216

      Pulmonary ventilation 216

      External respiration 217

      Ventilation/Perfusion 217

      Transport of gases 217

      Internal respiration 218

      Assessment of lung function 220

      Normal breath sounds (vesicular) 221

      Absent Sounds 221

      Wheeze 222

      Crackles 222

      The work of breathing 222

      Compliance 222

      Resistance 222

      Emphysema 222

      Asthma 223

      Obstructive sleep apnoea 224

      Prone positioning 224

      Conclusion 225

      References 226

      Chapter 18 Cardiac physiology 227
      Paul Sinnott

      Introduction 228

      Functions of the cardiovascular system 228

      Anatomy of the heart and great vessels 228

      Pericardium 229

      Layers of the heart 229

      Chambers of the heart 230

      Valves of the heart 230

      Coronary circulation 232

      Cardiac conduction system 235

      The cardiac cycle 236

      Cardiac output and blood pressure 237

      Regulation of heart rate 238

      Stroke volume 239

      The regulation of blood pressure 240

      The microcirculation 242

      Capillary exchange 243

      Effects of ventilation on the cardiovascular system 245

      Conclusion 245

      References 246

      Chapter 19 Cardiovascular critical care 247
      Alice Shaw and Paul Sinnott

      Introduction 248

      Cardiovascular assessment 248

      Heart rate and rhythm 248

      Atrial ectopic beats 249

      Ventricular ectopic beats 253

      Blood pressure 254

      Invasive blood pressure monitoring 255

      Central venous catheters (CVCs) and central venous pressure (CVP) 256

      Markers of organ and tissue perfusion 258

      Neurological status 258

      Urine output 258

      Blood results 259

      Advanced haemodynamic monitoring 260

      Cardiac pacing 262

      Nursing considerations and recommendations for practice 263

      Conclusion 263

      References 263

      Chapter 20 Fluids and electrolytes in critically ill patients 265
      Barry Hill

      Introduction 266

      The role of the critical care nurse 266

      Intravenous fluids 266

      Crystalloids versus colloids critical care 267

      Fluid management 268

      Third spacing 269

      Assessment and monitoring 269

      Training and education 271

      Electrolyte replacement therapy 271

      Management of hyperkalaemia 272

      Oral sodium and water 272

      Oral rehydration therapy (ORT) 272

      Oral bicarbonate 273

      Parenteral preparations for fluid and electrolyte imbalance 273

      Plasma and plasma substitutes 276

      Plasma substitutes 276

      Fluid overload 276

      The four Ds of fluid management 276

      Hyponatraemia 277

      Hypernatraemia 277

      Hypokalaemia 277

      Hyperkalaemia 277

      Hypophosphataemia 278

      Hypocalcaemia 278

      Hypomagnesaemia 278

      Conclusion 279

      References 279

      Chapter 21 Critical care emergencies 280
      Alexandra Gatehouse and Sadie Diamond-Fox

      Introduction 281

      A – Airway 282

      B – Breathing 290

      C – Circulation/Cardiovascular 291

      D – Disability 298

      E – Everything else (exposure, endocrine, electrolytes and environmental) 301

      Care of the patient post return of spontaneous circulation (ROSC) 307

      Critical care emergencies and human factors 307

      Debriefing 309

      Do-not-attempt-cardiopulmonary-resuscitation (DNACPR) and Recommended Summary Plan for Emergency Care and Treatment (ReSPECT) 309

      Conclusion 310

      References 310

      Chapter 22 Gastrointestinal critical care 313
      Anna Riley, Joe Box, and Aileen Aherne

      Introduction 314

      Anatomy and physiology 314

      GI monitoring and investigation in the critically ill 317

      Imaging and endoscopy 318

      Bowel charts and abnormal GI motility 320

      The acute abdomen in critical care 322

      Common surgical procedures cared for in critical care 325

      Post-operative monitoring 325

      Abdominal surgical drains 326

      Anaesthetics 326

      Post-operative complications 326

      Wound dehiscence 327

      GI pharmacology 327

      Conclusion 328

      References 328

      Chapter 23 Nutrition in critical care 330
      Barry Hill and Lorraine Mutrie

      Introduction 331

      Pathophysiology 331

      Fight or flight 332

      Resistance 332

      Exhaustion 332

      Nutritional screening and assessment 333

      Indirect calorimetry (IC) 333

      Routes of administration 334

      Nursing considerations and recommendations for practice 336

      Care of people with feeding tubes 336

      Glycaemic control 337

      Refeeding syndrome 338

      Discontinuing feed 339

      Nutritional guidance 339

      Conclusion 340

      References 341

      Chapter 24 Renal critical care 343
      Alexandra Gatehouse and Sadie Diamond-Fox

      Introduction 344

      Anatomy and physiology of the renal tract 344

      Vascular supply 344

      Renin-angiotensin-aldosterone system (RASS) 344

      The nephrons 345

      Control of plasma osmolality 346

      Electrolyte balance 346

      Acid-base balance 352

      Renal failure 352

      Acute kidney injury 353

      Classification of AKI 353

      Pathophysiology 353

      Organ cross-talk 354

      Risk factors for AKI 355

      Clinical features and examination 355

      Investigations 355

      Specific disorders associated with AKI 357

      Drug-induced renal damage 357

      Management of AKI 359

      Clinical features and examination 361

      Management 361

      Chronic kidney disease 362

      Management 362

      Diabetic nephropathy 362

      Continuous renal replacement therapy (CRRT) 364

      Dosing of CRRT 364

      Anticoagulation 364

      Drug dosing and RRT 367

      Kidney transplantation – critical care considerations 367

      Conclusion 368

      References 368

      Chapter 25 Endocrine critical care 370
      Geraldine Fitzgerald O’Connor and Emma Long

      Introduction 371

      Thyroid and parathyroid glands 371

      Disorders of the thyroid gland 371

      Thyroid crisis 372

      Parathyroid glands 372

      Disorders of the parathyroid glands 372

      Hypocalcaemia 373

      Pituitary gland 373

      Disorders of the pituitary gland 373

      Diabetes insipidus 374

      Pathophysiology 375

      Hyperglycaemia in the critically ill 376

      Diabetic emergencies 376

      Pathophysiology 380

      Conclusion 383

      References 384

      Chapter 26 Haematological and immunological critical care 385
      Barry Hill, Gerri Mortimore, and Pamela Arasen

      Introduction 386

      Normal physiology 386

      Blood components 386

      Haematopoiesis 387

      Disorders of erythrocytes 387

      B12 vitamin deficiency 387

      Sickle cell anaemia 388

      Genetic haemochromatosis 389

      Haemostasis 390

      Lymphoma 390

      Disseminated intravascular coagulation 393

      Thrombocytopenia 394

      Neutropenia and sepsis 394

      Vasculitis 396

      Blood transfusions in adults 397

      Blood sample collections 398

      Blood groups 398

      Compatibility 399

      Indications for blood transfusions 399

      Platelets 400

      Fresh frozen plasma (FFP) 400

      Cryoprecipitate 400

      Granulocytes 400

      Procedural safety 400

      Pre-procedure and sampling 400

      Administration of the blood product 400

      Post-procedural care 401

      Traceability 401

      Patient information 402

      Alternatives to blood transfusions 403

      Summary of SaBTO recommendations on consent 403

      Conclusion 408

      References 408

      Chapter 27 Musculoskeletal considerations in critical care 411
      Clare L. Wade and Helen Sanger

      Introduction 412

      Trauma 412

      Management of traumatic injury 413

      Intensive care unit-acquired weakness 415

      Assessment of musculoskeletal impairment or injury 418

      Management of musculoskeletal injury and impairment 419

      Conclusion 424

      References 424

      Chapter 28 Burn care within a critical care setting 426
      Nicole Lee

      Introduction 427

      Classification of burn wound depths 427

      Pathological considerations 429

      Burn size estimation 430

      An ABCDE approach to burn care 432

      Breathing 433

      Cardiovascular 433

      Disability (neurological assessment) 434

      Exposure (and everything else) 434

      Psychological support 434

      Acknowledgement 436

      References 436

      Chapter 29 Maternal critical care 438
      Wendy Pollock

      Introduction 439

      Epidemiology 439

      Adapted physiology 439

      Recognising clinical deterioration 441

      Nursing considerations and recommendations for practice 442

      Conclusion 448

      References 449

      Chapter 30 Critical care transfers 451
      Kirstin Geer, Mark Cannan, and Stuart Cox

      Inter-hospital and intra-hospital patient transfers 452

      Transfer of the critically ill adult 452

      Critical care bed and repatriation 456

      The risks of critical care transfer 457

      Preparation for transfer 458

      ABCDE process during critical care transfer 458

      Conclusion 469

      References 469

      Chapter 31 Rehabilitation after critical illness 470
      Helen Sanger and Clare L. Wade

      Introduction 471

      The impact of critical illness – what do we mean by morbidity? 471

      Describing physical functioning and morbidity 472

      Models of post-critical care morbidity 473

      Assessment 473

      Goals 475

      Key timepoints in RaCI 477

      Treatment 478

      National guidelines and standards 480

      Conclusion 481

      References 481

      Chapter 32 Dying and death 484
      Helen Merlane and Leonie Armstrong

      Introduction 485

      End-of-life care 485

      Palliative care 486

      Dying 486

      Recognising Dying 486

      Advance care planning 488

      Involve and support 489

      Nursing the dying patient 489

      The critical care environment 489

      Symptom management 490

      End-of-life care discharges from a critical care setting 491

      Care after death 494

      Conclusion 495

      References 495

      Index 497

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