Description
Book SynopsisDNA testing and its forensic analysis are recognized as the gold standard in forensic identification science methods. However, there is a great need for a hands-on step-by-step guide to teach the forensic DNA community how to interpret DNA mixtures, how to assign a likelihood ratio, and how to use the subsequent likelihood ratio when reporting interpretation conclusions.
Forensic DNA Profiling: A Practical Guide to Assigning Likelihood Ratios will provide a roadmap for labs all over the world and the next generation of analysts who need this foundational understanding. The techniques used in forensic DNA analysis are based upon the accepted principles of molecular biology. The interpretation of a good-quality DNA profile generated from a crime scene stain from a single-source donor provides an unambiguous result when using the most modern forensic DNA methods. Unfortunately, many crime scene profiles are not single source. They are described as mixed
Table of Contents
1: An Introduction and Review of DNA Profile Interpretation
2: An Introduction to Statistics and Proposition Setting
3: Assigning the LR: Single-Source Examples Population Genetics Models
4: Application of the Binary LR for Mixtures
5: LRs Considering Relatives as Alternate Contributors
6: Probabilistic Genotyping: Semicontinuous Models
7: Probabilistic Genotyping: Continuous Models
8: Considerations on Validation of Probabilistic Genotyping Software
Appendix 1: Allele Frequencies
Appendix 2: Model Answers
