Description
Book SynopsisTable of Contents51. Defining thresholds for vitamin D I: scientific rationale for serum 25-hydroxyvitamin D cutoffs of 25 and 50 nmol/L; 52. Defining thresholds for vitamin D II; 53. Methods of evaluating population studies of vitamin D: strengths and weaknesses; 54. Worldwide vitamin D status; 55. Vitamin D in fooddCompounds, stability, sources; 56. Determinants of vitamin D levels from sun exposure: a global perspective; 57. Vitamin D supplement use as a public health strategy to augment diet and sustain population adequacy; 58. Vitamin D and food fortification; 59. Bariatric surgery, vitamin D, and bone loss; 60. Genetic determinants of 25-hydroxyvitamin D concentrations; 61. Effect of vitamin D on health and disease: evidence from Mendelian randomization; 62. Growth plate histology, bone histomorphometry, and radiologic features of nutritional rickets and osteomalacia; 63. Vitamin D deficiency and nutritional rickets in infants and children; 64. Clinical disorders of phosphate homeostasis; 65. The hypocalcemic disorders; 66. Vitamin D hydroxylationedeficient rickets, type 1A; 67. The role of genetic variation in CYP2R1, the principal vitamin D 25- hydroxylase, and CYP3A4 in vitamin D homeostasis; 68. Hereditary 1,25-dihydroxyvitamin D resistant rickets (VDDR-2A); 69. Infantile hypercalcemia and CYP24A1 mutations; 70. Vitamin D and osteoporosis; 71. Adult vitamin D deficiencydfracture and fall prevention: findings from randomized controlled trials; 72. Randomized clinical trials of vitamin D and bone health; 73. Calcifediol as a therapeutic; 74. Vitamin D and organ transplantation; 75. Vitamin D, obesity, the metabolic syndrome and its sequelae; 76. The role of vitamin D in type 2 diabetes; 77. Liver metabolism and disease; 78. Vitamin D, hypertension, and cardiovascular disease; 79. Vitamin D and renal disease; 80. Vitamin D and kidney stones; 81. Hypercalcemia due to vitamin D toxicity; 82. Vitamin D and Paget’s disease; 83. Vitamin D metabolism and disorders in companion animals; 84. Overview of vitamin D actions in cancer; 85. Vitamin D status and cancer incidence, mortality, and prognosis; 86. Antiproliferative and immunoregulatory actions of vitamin D derivatives on hematological malignancies: control of differentiation, proliferation, and cell death; 87. Vitamin D, inflammation, and cancer; 88. Vitamin D actions in mammary gland and breast cancer; 89. Vitamin D and colorectal cancer; 90. Vitamin D in the management of lung cancer: influence of tumor stage, tumor genotype, and treatment modality; 91. Vitamin D and prostate cancer; 92. Vitamin D and pancreatic cancer; 93. Sunlight, skin cancer and vitamin D; 94 . Vitamin D and antibacterial immunity; 95. Vitamin D and antiviral immunity; 96. Vitamin D and adaptive immunity in health and disease; 97. Vitamin D, microbiota, and inflammatory bowel disease; 98. Vitamin D and tuberculosis; 99. The role of vitamin D in COVID-19; 100 . Vitamin D and type 1 diabetes; 101. Vitamin D mechanisms of protection in multiple sclerosis; 102. Vitamin D and the epidemiology of multiple sclerosis; 103. Vitamin D and rheumatoid arthritis; 104. Psoriasis and other skin disorders; 105. Vitamin D, acute respiratory infection, and Asthma/COPD; 106. Vitamin D and acute illness; Index for Volume 2
