Description
Book SynopsisDrug abuse has been, and continues to be, a global societal issue with diverse sets of impacts. Drugs of Abuse: Pharmacology and Molecular Mechanisms introduces the basic principles of pharmacology and neuroscience of drug abuse. Understanding the chemistry of commonly abused drugs and their impact on brain function will provide students and researchers with a more profound understanding of the molecular basis of drug abuse and addiction.
Drugs of Abuse: Pharmacology and Molecular Mechanisms opens with a brief history of drug use and abuse. Subsequent sections look at specific families of drugs, including stimulants, depressants, and hallucinogens among others, and explore how their chemical make-up interacts with brain function. The final chapter provides a brief overview of clinical substance abuse treatment.
Providing a concise, accessible introductory overview of the topic, Drugs of Abuse: Pharmacology and Molecular Mechanisms will be a valuabl
Trade Review
“Overall, an excellent resource for understanding current information about drugs of abuse that will appeal to a wide audience. Summing Up: Highly recommended. Students of all levels, general readers, and professionals/practitioners.” (Choice, 1 November 2014)
Table of Contents
Contributor List ix
Preface xi
Acknowledgments xiii
1 Introduction 1
Part I Stimulants 13
2 Biochemistry of Neurotransmission 15
3 Amphetamine and Amphetamine Analogs 33
4 Cocaine 65
Part II Depressants, Sedative Hypnotics, and Anxiolytics 75
5 Benzodiazepines and Barbiturates 77
Part III Dissociative Anesthetics 93
6 Phencyclidine and Ketamine 95
7 γ Hydroxybutyrate 105
Part IV Analgesics 115
8 Morphine and Morphine Analogs 117
Carlos Cepeda
Part V Hallucinogens 135
9 Lysergic Acid Diethylamide and Mescaline 137
10 Marijuana 153
11 Inhalants and Miscellaneous Drugs 167
Part VI Recovery and Relapse 181
12 Treatment of Substance Dependency 183
Mark DeAntonio
Index 189
