Description

Book Synopsis
COGNITIVE INTELLIGENCE AND BIG DATA IN HEALTHCARE Applications of cognitive intelligence, advanced communication, and computational methods can drive healthcare research and enhance existing traditional methods in disease detection and management and prevention. As health is the foremost factor affecting the quality of human life, it is necessary to understand how the human body is functioning by processing health data obtained from various sources more quickly. Since an enormous amount of data is generated during data processing, a cognitive computing system could be applied to respond to queries, thereby assisting in customizing intelligent recommendations. This decision-making process could be improved by the deployment of cognitive computing techniques in healthcare, allowing for cutting-edge techniques to be integrated into healthcare to provide intelligent services in various healthcare applications. This book tackles all these issues and provides insight into these diversifie

Table of Contents

Preface xv

1 Era of Computational Cognitive Techniques in Healthcare Systems 1
Deependra Rastogi, Varun Tiwari, Shobhit Kumar and Prabhat Chandra Gupta

1.1 Introduction 2

1.2 Cognitive Science 3

1.3 Gap Between Classical Theory of Cognition 4

1.4 Cognitive Computing’s Evolution 6

1.5 The Coming Era of Cognitive Computing 7

1.6 Cognitive Computing Architecture 9

1.6.1 The Internet-of-Things and Cognitive Computing 10

1.6.2 Big Data and Cognitive Computing 11

1.6.3 Cognitive Computing and Cloud Computing 13

1.7 Enabling Technologies in Cognitive Computing 13

1.7.1 Reinforcement Learning and Cognitive Computing 13

1.7.2 Cognitive Computing with Deep Learning 15

1.7.2.1 Relational Technique and Perceptual Technique 15

1.7.2.2 Cognitive Computing and Image Understanding 16

1.8 Intelligent Systems in Healthcare 17

1.8.1 Intelligent Cognitive System in Healthcare (Why and How) 20

1.9 The Cognitive Challenge 32

1.9.1 Case Study: Patient Evacuation 32

1.9.2 Case Study: Anesthesiology 32

1.10 Conclusion 34

References 35

2 Proposal of a Metaheuristic Algorithm of Cognitive Computing for Classification of Erythrocytes and Leukocytes in Healthcare Informatics 41
Ana Carolina Borges Monteiro, Reinaldo Padilha França, Rangel Arthur and Yuzo Iano

2.1 Introduction 42

2.2 Literature Concept 44

2.2.1 Cognitive Computing Concept 44

2.2.2 Neural Networks Concepts 47

2.2.3 Convolutional Neural Network 49

2.2.4 Deep Learning 52

2.3 Materials and Methods (Metaheuristic Algorithm Proposal) 55

2.4 Case Study and Discussion 57

2.5 Conclusions with Future Research Scopes 60

References 61

3 Convergence of Big Data and Cognitive Computing in Healthcare 67
R. Sathiyaraj, U. Rahamathunnisa, M.V. Jagannatha Reddy and T. Parameswaran

3.1 Introduction 68

3.2 Literature Review 70

3.2.1 Role of Cognitive Computing in Healthcare Applications 70

3.2.2 Research Problem Study by IBM 73

3.2.3 Purpose of Big Data in Healthcare 74

3.2.4 Convergence of Big Data with Cognitive Computing 74

3.2.4.1 Smart Healthcare 74

3.2.4.2 Big Data and Cognitive Computing-Based Smart Healthcare 75

3.3 Using Cognitive Computing and Big Data, a Smart Healthcare Framework for EEG Pathology Detection and Classification 76

3.3.1 EEG Pathology Diagnoses 76

3.3.2 Cognitive–Big Data-Based Smart Healthcare 77

3.3.3 System Architecture 79

3.3.4 Detection and Classification of Pathology 80

3.3.4.1 EEG Preprocessing and Illustration 80

3.3.4.2 CNN Model 80

3.3.5 Case Study 81

3.4 An Approach to Predict Heart Disease Using Integrated Big Data and Cognitive Computing in Cloud 83

3.4.1 Cloud Computing with Big Data in Healthcare 86

3.4.2 Heart Diseases 87

3.4.3 Healthcare Big Data Techniques 88

3.4.3.1 Rule Set Classifiers 88

3.4.3.2 Neuro Fuzzy Classifiers 89

3.4.3.3 Experimental Results 91

3.5 Conclusion 92

References 93

4 IoT for Health, Safety, Well-Being, Inclusion, and Active Aging 97
R. Indrakumari, Nilanjana Pradhan, Shrddha Sagar and Kiran Singh

4.1 Introduction 98

4.2 The Role of Technology in an Aging Society 99

4.3 Literature Survey 100

4.4 Health Monitoring 101

4.5 Nutrition Monitoring 105

4.6 Stress-Log: An IoT-Based Smart Monitoring System 106

4.7 Active Aging 108

4.8 Localization 108

4.9 Navigation Care 111

4.10 Fall Monitoring 113

4.10.1 Fall Detection System Architecture 114

4.10.2 Wearable Device 114

4.10.3 Wireless Communication Network 114

4.10.4 Smart IoT Gateway 115

4.10.5 Interoperability 115

4.10.6 Transformation of Data 115

4.10.7 Analyzer for Big Data 115

4.11 Conclusion 115

References 116

5 Influence of Cognitive Computing in Healthcare Applications 121
Lucia Agnes Beena T. and Vinolyn Vijaykumar

5.1 Introduction 122

5.2 Bond Between Big Data and Cognitive Computing 124

5.3 Need for Cognitive Computing in Healthcare 126

5.4 Conceptual Model Linking Big Data and Cognitive Computing 128

5.4.1 Significance of Big Data 128

5.4.2 The Need for Cognitive Computing 129

5.4.3 The Association Between the Big Data and Cognitive Computing 130

5.4.4 The Advent of Cognition in Healthcare 132

5.5 IBM’s Watson and Cognitive Computing 133

5.5.1 Industrial Revolution with Watson 134

5.5.2 The IBM’s Cognitive Computing Endeavour in Healthcare 135

5.6 Future Directions 137

5.6.1 Retail 138

5.6.2 Research 139

5.6.3 Travel 139

5.6.4 Security and Threat Detection 139

5.6.5 Cognitive Training Tools 140

5.7 Conclusion 141

References 141

6 An Overview of the Computational Cognitive from a Modern Perspective, Its Techniques and Application Potential in Healthcare Systems 145
Reinaldo Padilha França, Ana Carolina Borges Monteiro, Rangel Arthur and Yuzo Iano

6.1 Introduction 146

6.2 Literature Concept 148

6.2.1 Cognitive Computing Concept 148

6.2.1.1 Application Potential 151

6.2.2 Cognitive Computing in Healthcare 153

6.2.3 Deep Learning in Healthcare 157

6.2.4 Natural Language Processing in Healthcare 160

6.3 Discussion 162

6.4 Trends 163

6.5 Conclusions 164

References 165

7 Protecting Patient Data with 2F- Authentication 169
G. S. Pradeep Ghantasala, Anu Radha Reddy and R. Mohan Krishna Ayyappa

7.1 Introduction 170

7.2 Literature Survey 175

7.3 Two-Factor Authentication 177

7.3.1 Novel Features of Two-Factor Authentication 178

7.3.2 Two-Factor Authentication Sorgen 178

7.3.3 Two-Factor Security Libraries 179

7.3.4 Challenges for Fitness Concern 180

7.4 Proposed Methodology 181

7.5 Medical Treatment and the Preservation of Records 186

7.5.1 Remote Method of Control 187

7.5.2 Enabling Healthcare System Technology 187

7.6 Conclusion 189

References 190

8 Data Analytics for Healthcare Monitoring and Inferencing 197
Gend Lal Prajapati, Rachana Raghuwanshi and Rambabu Raghuwanshi

8.1 An Overview of Healthcare Systems 198

8.2 Need of Healthcare Systems 198

8.3 Basic Principle of Healthcare Systems 199

8.4 Design and Recommended Structure of Healthcare Systems 199

8.4.1 Healthcare System Designs on the Basis of these Parameters 200

8.4.2 Details of Healthcare Organizational Structure 201

8.5 Various Challenges in Conventional Existing Healthcare System 202

8.6 Health Informatics 202

8.7 Information Technology Use in Healthcare Systems 203

8.8 Details of Various Information Technology Application Use in Healthcare Systems 203

8.9 Healthcare Information Technology Makes it Possible to Manage Patient Care and Exchange of Health Information Data, Details are Given Below 204

8.10 Barriers and Challenges to Implementation of Information Technology in Healthcare Systems 205

8.11 Healthcare Data Analytics 206

8.12 Healthcare as a Concept 206

8.13 Healthcare’s Key Technologies 207

8.14 The Present State of Smart Healthcare Application 207

8.15 Data Analytics with Machine Learning Use in Healthcare Systems 208

8.16 Benefit of Data Analytics in Healthcare System 210

8.17 Data Analysis and Visualization: COVID-19 Case Study in India 210

8.18 Bioinformatics Data Analytics 222

8.18.1 Notion of Bioinformatics 222

8.18.2 Bioinformatics Data Challenges 222

8.18.3 Sequence Analysis 222

8.18.4 Applications 223

8.18.5 COVID-19: A Bioinformatics Approach 224

8.19 Conclusion 224

References 225

9 Features Optimistic Approach for the Detection of Parkinson’s Disease 229
R. Shantha Selva Kumari, L. Vaishalee and P. Malavikha

9.1 Introduction 230

9.1.1 Parkinson’s Disease 230

9.1.2 Spect Scan 231

9.2 Literature Survey 232

9.3 Methods and Materials 233

9.3.1 Database Details 233

9.3.2 Procedure 234

9.3.3 Pre-Processing Done by PPMI 235

9.3.4 Image Analysis and Features Extraction 235

9.3.4.1 Image Slicing 235

9.3.4.2 Intensity Normalization 237

9.3.4.3 Image Segmentation 239

9.3.4.4 Shape Features Extraction 240

9.3.4.5 SBR Features 241

9.3.4.6 Feature Set Analysis 242

9.3.4.7 Surface Fitting 242

9.3.5 Classification Modeling 243

9.3.6 Feature Importance Estimation 246

9.3.6.1 Need for Analysis of Important Features 246

9.3.6.2 Random Forest 247

9.4 Results and Discussion 248

9.4.1 Segmentation 248

9.4.2 Shape Analysis 249

9.4.3 Classification 249

9.5 Conclusion 252

References 253

10 Big Data Analytics in Healthcare 257
Akanksha Sharma, Rishabha Malviya and Ramji Gupta

10.1 Introduction 258

10.2 Need for Big Data Analytics 260

10.3 Characteristics of Big Data 264

10.3.1 Volume 264

10.3.2 Velocity 265

10.3.3 Variety 265

10.3.4 Veracity 265

10.3.5 Value 265

10.3.6 Validity 265

10.3.7 Variability 266

10.3.8 Viscosity 266

10.3.9 Virality 266

10.3.10 Visualization 266

10.4 Big Data Analysis in Disease Treatment and Management 267

10.4.1 For Diabetes 267

10.4.2 For Heart Disease 268

10.4.3 For Chronic Disease 270

10.4.4 For Neurological Disease 271

10.4.5 For Personalized Medicine 271

10.5 Big Data: Databases and Platforms in Healthcare 279

10.6 Importance of Big Data in Healthcare 285

10.6.1 Evidence-Based Care 285

10.6.2 Reduced Cost of Healthcare 285

10.6.3 Increases the Participation of Patients in the Care Process 285

10.6.4 The Implication in Health Surveillance 285

10.6.5 Reduces Mortality Rate 285

10.6.6 Increase of Communication Between Patients and Healthcare Providers 286

10.6.7 Early Detection of Fraud and Security Threats in Health Management 286

10.6.8 Improvement in the Care Quality 286

10.7 Application of Big Data Analytics 286

10.7.1 Image Processing 286

10.7.2 Signal Processing 287

10.7.3 Genomics 288

10.7.4 Bioinformatics Applications 289

10.7.5 Clinical Informatics Application 291

10.8 Conclusion 293

References 294

11 Case Studies of Cognitive Computing in Healthcare Systems: Disease Prediction, Genomics Studies, Medical Image Analysis, Patient Care, Medical Diagnostics, Drug Discovery 303
V. Sathananthavathi and G. Indumathi

11.1 Introduction 304

11.1.1 Glaucoma 304

11.2 Literature Survey 306

11.3 Methodology 309

11.3.1 Sclera Segmentation 310

11.3.1.1 Fully Convolutional Network 311

11.3.2 Pupil/Iris Ratio 313

11.3.2.1 Canny Edge Detection 314

11.3.2.2 Mean Redness Level (MRL) 315

11.3.2.3 Red Area Percentage (RAP) 316

11.4 Results and Discussion 317

11.4.1 Feature Extraction from Frontal Eye Images 318

11.4.1.1 Level of Mean Redness (MRL) 318

11.4.1.2 Percentage of Red Area (RAP) 318

11.4.2 Images of the Frontal Eye Pupil/Iris Ratio 318

11.4.2.1 Histogram Equalization 319

11.4.2.2 Morphological Reconstruction 319

11.4.2.3 Canny Edge Detection 319

11.4.2.4 Adaptive Thresholding 320

11.4.2.5 Circular Hough Transform 321

11.4.2.6 Classification 322

11.5 Conclusion and Future Work 324

References 325

12 State of Mental Health and Social Media: Analysis, Challenges, Advancements 327
Atul Pankaj Patil, Kusum Lata Jain, Smaranika Mohapatra and Suyesha Singh

12.1 Introduction 328

12.2 Introduction to Big Data and Data Mining 328

12.3 Role of Sentimental Analysis in the Healthcare Sector 330

12.4 Case Study: Analyzing Mental Health 332

12.4.1 Problem Statement 332

12.4.2 Research Objectives 333

12.4.3 Methodology and Framework 333

12.4.3.1 Big 5 Personality Model 333

12.4.3.2 Openness to Explore 334

12.4.3.3 Methodology 335

12.4.3.4 Detailed Design Methodologies 340

12.4.3.5 Work Done Details as Required 341

12.5 Results and Discussion 343

12.6 Conclusion and Future 345

References 346

13 Applications of Artificial Intelligence, Blockchain, and Internet-of-Things in Management of Chronic Disease 349
Geetanjali, Rishabha Malviya, Rajendra Awasthi, Pramod Kumar Sharma, Nidhi Kala, Vinod Kumar and Sanjay Kumar Yadav

13.1 Introduction 350

13.2 Artificial Intelligence and Management of Chronic Diseases 351

13.3 Blockchain and Healthcare 354

13.3.1 Blockchain and Healthcare Management of Chronic Disease 355

13.4 Internet-of-Things and Healthcare Management of Chronic Disease 358

13.5 Conclusions 360

References 360

14 Research Challenges and Future Directions in Applying Cognitive Computing in the Healthcare Domain 367
BKSP Kumar Raju Alluri

14.1 Introduction 367

14.2 Cognitive Computing Framework in Healthcare 371

14.3 Benefits of Using Cognitive Computing for Healthcare 372

14.4 Applications of Deploying Cognitive Assisted Technology in Healthcare Management 374

14.4.1 Using Cognitive Services for a Patient’s Healthcare Management 375

14.4.2 Using Cognitive Services for Healthcare Providers 376

14.5 Challenges in Using the Cognitive Assistive Technology in Healthcare Management 377

14.6 Future Directions for Extending Heathcare Services Using CATs 380

14.7 Addressing CAT Challenges in Healthcare as a General Framework 384

14.8 Conclusion 384

References 385

Index 391

Cognitive Intelligence and Big Data in Healthcare

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    A Hardback by Sumathi, T. Poongodi, B. Balamurugan


      View other formats and editions of Cognitive Intelligence and Big Data in Healthcare by Sumathi

      Publisher: John Wiley & Sons Inc
      Publication Date: 8/30/2022 12:00:00 AM
      ISBN13: 9781119768883, 978-1119768883
      ISBN10: 1119768888

      Description

      Book Synopsis
      COGNITIVE INTELLIGENCE AND BIG DATA IN HEALTHCARE Applications of cognitive intelligence, advanced communication, and computational methods can drive healthcare research and enhance existing traditional methods in disease detection and management and prevention. As health is the foremost factor affecting the quality of human life, it is necessary to understand how the human body is functioning by processing health data obtained from various sources more quickly. Since an enormous amount of data is generated during data processing, a cognitive computing system could be applied to respond to queries, thereby assisting in customizing intelligent recommendations. This decision-making process could be improved by the deployment of cognitive computing techniques in healthcare, allowing for cutting-edge techniques to be integrated into healthcare to provide intelligent services in various healthcare applications. This book tackles all these issues and provides insight into these diversifie

      Table of Contents

      Preface xv

      1 Era of Computational Cognitive Techniques in Healthcare Systems 1
      Deependra Rastogi, Varun Tiwari, Shobhit Kumar and Prabhat Chandra Gupta

      1.1 Introduction 2

      1.2 Cognitive Science 3

      1.3 Gap Between Classical Theory of Cognition 4

      1.4 Cognitive Computing’s Evolution 6

      1.5 The Coming Era of Cognitive Computing 7

      1.6 Cognitive Computing Architecture 9

      1.6.1 The Internet-of-Things and Cognitive Computing 10

      1.6.2 Big Data and Cognitive Computing 11

      1.6.3 Cognitive Computing and Cloud Computing 13

      1.7 Enabling Technologies in Cognitive Computing 13

      1.7.1 Reinforcement Learning and Cognitive Computing 13

      1.7.2 Cognitive Computing with Deep Learning 15

      1.7.2.1 Relational Technique and Perceptual Technique 15

      1.7.2.2 Cognitive Computing and Image Understanding 16

      1.8 Intelligent Systems in Healthcare 17

      1.8.1 Intelligent Cognitive System in Healthcare (Why and How) 20

      1.9 The Cognitive Challenge 32

      1.9.1 Case Study: Patient Evacuation 32

      1.9.2 Case Study: Anesthesiology 32

      1.10 Conclusion 34

      References 35

      2 Proposal of a Metaheuristic Algorithm of Cognitive Computing for Classification of Erythrocytes and Leukocytes in Healthcare Informatics 41
      Ana Carolina Borges Monteiro, Reinaldo Padilha França, Rangel Arthur and Yuzo Iano

      2.1 Introduction 42

      2.2 Literature Concept 44

      2.2.1 Cognitive Computing Concept 44

      2.2.2 Neural Networks Concepts 47

      2.2.3 Convolutional Neural Network 49

      2.2.4 Deep Learning 52

      2.3 Materials and Methods (Metaheuristic Algorithm Proposal) 55

      2.4 Case Study and Discussion 57

      2.5 Conclusions with Future Research Scopes 60

      References 61

      3 Convergence of Big Data and Cognitive Computing in Healthcare 67
      R. Sathiyaraj, U. Rahamathunnisa, M.V. Jagannatha Reddy and T. Parameswaran

      3.1 Introduction 68

      3.2 Literature Review 70

      3.2.1 Role of Cognitive Computing in Healthcare Applications 70

      3.2.2 Research Problem Study by IBM 73

      3.2.3 Purpose of Big Data in Healthcare 74

      3.2.4 Convergence of Big Data with Cognitive Computing 74

      3.2.4.1 Smart Healthcare 74

      3.2.4.2 Big Data and Cognitive Computing-Based Smart Healthcare 75

      3.3 Using Cognitive Computing and Big Data, a Smart Healthcare Framework for EEG Pathology Detection and Classification 76

      3.3.1 EEG Pathology Diagnoses 76

      3.3.2 Cognitive–Big Data-Based Smart Healthcare 77

      3.3.3 System Architecture 79

      3.3.4 Detection and Classification of Pathology 80

      3.3.4.1 EEG Preprocessing and Illustration 80

      3.3.4.2 CNN Model 80

      3.3.5 Case Study 81

      3.4 An Approach to Predict Heart Disease Using Integrated Big Data and Cognitive Computing in Cloud 83

      3.4.1 Cloud Computing with Big Data in Healthcare 86

      3.4.2 Heart Diseases 87

      3.4.3 Healthcare Big Data Techniques 88

      3.4.3.1 Rule Set Classifiers 88

      3.4.3.2 Neuro Fuzzy Classifiers 89

      3.4.3.3 Experimental Results 91

      3.5 Conclusion 92

      References 93

      4 IoT for Health, Safety, Well-Being, Inclusion, and Active Aging 97
      R. Indrakumari, Nilanjana Pradhan, Shrddha Sagar and Kiran Singh

      4.1 Introduction 98

      4.2 The Role of Technology in an Aging Society 99

      4.3 Literature Survey 100

      4.4 Health Monitoring 101

      4.5 Nutrition Monitoring 105

      4.6 Stress-Log: An IoT-Based Smart Monitoring System 106

      4.7 Active Aging 108

      4.8 Localization 108

      4.9 Navigation Care 111

      4.10 Fall Monitoring 113

      4.10.1 Fall Detection System Architecture 114

      4.10.2 Wearable Device 114

      4.10.3 Wireless Communication Network 114

      4.10.4 Smart IoT Gateway 115

      4.10.5 Interoperability 115

      4.10.6 Transformation of Data 115

      4.10.7 Analyzer for Big Data 115

      4.11 Conclusion 115

      References 116

      5 Influence of Cognitive Computing in Healthcare Applications 121
      Lucia Agnes Beena T. and Vinolyn Vijaykumar

      5.1 Introduction 122

      5.2 Bond Between Big Data and Cognitive Computing 124

      5.3 Need for Cognitive Computing in Healthcare 126

      5.4 Conceptual Model Linking Big Data and Cognitive Computing 128

      5.4.1 Significance of Big Data 128

      5.4.2 The Need for Cognitive Computing 129

      5.4.3 The Association Between the Big Data and Cognitive Computing 130

      5.4.4 The Advent of Cognition in Healthcare 132

      5.5 IBM’s Watson and Cognitive Computing 133

      5.5.1 Industrial Revolution with Watson 134

      5.5.2 The IBM’s Cognitive Computing Endeavour in Healthcare 135

      5.6 Future Directions 137

      5.6.1 Retail 138

      5.6.2 Research 139

      5.6.3 Travel 139

      5.6.4 Security and Threat Detection 139

      5.6.5 Cognitive Training Tools 140

      5.7 Conclusion 141

      References 141

      6 An Overview of the Computational Cognitive from a Modern Perspective, Its Techniques and Application Potential in Healthcare Systems 145
      Reinaldo Padilha França, Ana Carolina Borges Monteiro, Rangel Arthur and Yuzo Iano

      6.1 Introduction 146

      6.2 Literature Concept 148

      6.2.1 Cognitive Computing Concept 148

      6.2.1.1 Application Potential 151

      6.2.2 Cognitive Computing in Healthcare 153

      6.2.3 Deep Learning in Healthcare 157

      6.2.4 Natural Language Processing in Healthcare 160

      6.3 Discussion 162

      6.4 Trends 163

      6.5 Conclusions 164

      References 165

      7 Protecting Patient Data with 2F- Authentication 169
      G. S. Pradeep Ghantasala, Anu Radha Reddy and R. Mohan Krishna Ayyappa

      7.1 Introduction 170

      7.2 Literature Survey 175

      7.3 Two-Factor Authentication 177

      7.3.1 Novel Features of Two-Factor Authentication 178

      7.3.2 Two-Factor Authentication Sorgen 178

      7.3.3 Two-Factor Security Libraries 179

      7.3.4 Challenges for Fitness Concern 180

      7.4 Proposed Methodology 181

      7.5 Medical Treatment and the Preservation of Records 186

      7.5.1 Remote Method of Control 187

      7.5.2 Enabling Healthcare System Technology 187

      7.6 Conclusion 189

      References 190

      8 Data Analytics for Healthcare Monitoring and Inferencing 197
      Gend Lal Prajapati, Rachana Raghuwanshi and Rambabu Raghuwanshi

      8.1 An Overview of Healthcare Systems 198

      8.2 Need of Healthcare Systems 198

      8.3 Basic Principle of Healthcare Systems 199

      8.4 Design and Recommended Structure of Healthcare Systems 199

      8.4.1 Healthcare System Designs on the Basis of these Parameters 200

      8.4.2 Details of Healthcare Organizational Structure 201

      8.5 Various Challenges in Conventional Existing Healthcare System 202

      8.6 Health Informatics 202

      8.7 Information Technology Use in Healthcare Systems 203

      8.8 Details of Various Information Technology Application Use in Healthcare Systems 203

      8.9 Healthcare Information Technology Makes it Possible to Manage Patient Care and Exchange of Health Information Data, Details are Given Below 204

      8.10 Barriers and Challenges to Implementation of Information Technology in Healthcare Systems 205

      8.11 Healthcare Data Analytics 206

      8.12 Healthcare as a Concept 206

      8.13 Healthcare’s Key Technologies 207

      8.14 The Present State of Smart Healthcare Application 207

      8.15 Data Analytics with Machine Learning Use in Healthcare Systems 208

      8.16 Benefit of Data Analytics in Healthcare System 210

      8.17 Data Analysis and Visualization: COVID-19 Case Study in India 210

      8.18 Bioinformatics Data Analytics 222

      8.18.1 Notion of Bioinformatics 222

      8.18.2 Bioinformatics Data Challenges 222

      8.18.3 Sequence Analysis 222

      8.18.4 Applications 223

      8.18.5 COVID-19: A Bioinformatics Approach 224

      8.19 Conclusion 224

      References 225

      9 Features Optimistic Approach for the Detection of Parkinson’s Disease 229
      R. Shantha Selva Kumari, L. Vaishalee and P. Malavikha

      9.1 Introduction 230

      9.1.1 Parkinson’s Disease 230

      9.1.2 Spect Scan 231

      9.2 Literature Survey 232

      9.3 Methods and Materials 233

      9.3.1 Database Details 233

      9.3.2 Procedure 234

      9.3.3 Pre-Processing Done by PPMI 235

      9.3.4 Image Analysis and Features Extraction 235

      9.3.4.1 Image Slicing 235

      9.3.4.2 Intensity Normalization 237

      9.3.4.3 Image Segmentation 239

      9.3.4.4 Shape Features Extraction 240

      9.3.4.5 SBR Features 241

      9.3.4.6 Feature Set Analysis 242

      9.3.4.7 Surface Fitting 242

      9.3.5 Classification Modeling 243

      9.3.6 Feature Importance Estimation 246

      9.3.6.1 Need for Analysis of Important Features 246

      9.3.6.2 Random Forest 247

      9.4 Results and Discussion 248

      9.4.1 Segmentation 248

      9.4.2 Shape Analysis 249

      9.4.3 Classification 249

      9.5 Conclusion 252

      References 253

      10 Big Data Analytics in Healthcare 257
      Akanksha Sharma, Rishabha Malviya and Ramji Gupta

      10.1 Introduction 258

      10.2 Need for Big Data Analytics 260

      10.3 Characteristics of Big Data 264

      10.3.1 Volume 264

      10.3.2 Velocity 265

      10.3.3 Variety 265

      10.3.4 Veracity 265

      10.3.5 Value 265

      10.3.6 Validity 265

      10.3.7 Variability 266

      10.3.8 Viscosity 266

      10.3.9 Virality 266

      10.3.10 Visualization 266

      10.4 Big Data Analysis in Disease Treatment and Management 267

      10.4.1 For Diabetes 267

      10.4.2 For Heart Disease 268

      10.4.3 For Chronic Disease 270

      10.4.4 For Neurological Disease 271

      10.4.5 For Personalized Medicine 271

      10.5 Big Data: Databases and Platforms in Healthcare 279

      10.6 Importance of Big Data in Healthcare 285

      10.6.1 Evidence-Based Care 285

      10.6.2 Reduced Cost of Healthcare 285

      10.6.3 Increases the Participation of Patients in the Care Process 285

      10.6.4 The Implication in Health Surveillance 285

      10.6.5 Reduces Mortality Rate 285

      10.6.6 Increase of Communication Between Patients and Healthcare Providers 286

      10.6.7 Early Detection of Fraud and Security Threats in Health Management 286

      10.6.8 Improvement in the Care Quality 286

      10.7 Application of Big Data Analytics 286

      10.7.1 Image Processing 286

      10.7.2 Signal Processing 287

      10.7.3 Genomics 288

      10.7.4 Bioinformatics Applications 289

      10.7.5 Clinical Informatics Application 291

      10.8 Conclusion 293

      References 294

      11 Case Studies of Cognitive Computing in Healthcare Systems: Disease Prediction, Genomics Studies, Medical Image Analysis, Patient Care, Medical Diagnostics, Drug Discovery 303
      V. Sathananthavathi and G. Indumathi

      11.1 Introduction 304

      11.1.1 Glaucoma 304

      11.2 Literature Survey 306

      11.3 Methodology 309

      11.3.1 Sclera Segmentation 310

      11.3.1.1 Fully Convolutional Network 311

      11.3.2 Pupil/Iris Ratio 313

      11.3.2.1 Canny Edge Detection 314

      11.3.2.2 Mean Redness Level (MRL) 315

      11.3.2.3 Red Area Percentage (RAP) 316

      11.4 Results and Discussion 317

      11.4.1 Feature Extraction from Frontal Eye Images 318

      11.4.1.1 Level of Mean Redness (MRL) 318

      11.4.1.2 Percentage of Red Area (RAP) 318

      11.4.2 Images of the Frontal Eye Pupil/Iris Ratio 318

      11.4.2.1 Histogram Equalization 319

      11.4.2.2 Morphological Reconstruction 319

      11.4.2.3 Canny Edge Detection 319

      11.4.2.4 Adaptive Thresholding 320

      11.4.2.5 Circular Hough Transform 321

      11.4.2.6 Classification 322

      11.5 Conclusion and Future Work 324

      References 325

      12 State of Mental Health and Social Media: Analysis, Challenges, Advancements 327
      Atul Pankaj Patil, Kusum Lata Jain, Smaranika Mohapatra and Suyesha Singh

      12.1 Introduction 328

      12.2 Introduction to Big Data and Data Mining 328

      12.3 Role of Sentimental Analysis in the Healthcare Sector 330

      12.4 Case Study: Analyzing Mental Health 332

      12.4.1 Problem Statement 332

      12.4.2 Research Objectives 333

      12.4.3 Methodology and Framework 333

      12.4.3.1 Big 5 Personality Model 333

      12.4.3.2 Openness to Explore 334

      12.4.3.3 Methodology 335

      12.4.3.4 Detailed Design Methodologies 340

      12.4.3.5 Work Done Details as Required 341

      12.5 Results and Discussion 343

      12.6 Conclusion and Future 345

      References 346

      13 Applications of Artificial Intelligence, Blockchain, and Internet-of-Things in Management of Chronic Disease 349
      Geetanjali, Rishabha Malviya, Rajendra Awasthi, Pramod Kumar Sharma, Nidhi Kala, Vinod Kumar and Sanjay Kumar Yadav

      13.1 Introduction 350

      13.2 Artificial Intelligence and Management of Chronic Diseases 351

      13.3 Blockchain and Healthcare 354

      13.3.1 Blockchain and Healthcare Management of Chronic Disease 355

      13.4 Internet-of-Things and Healthcare Management of Chronic Disease 358

      13.5 Conclusions 360

      References 360

      14 Research Challenges and Future Directions in Applying Cognitive Computing in the Healthcare Domain 367
      BKSP Kumar Raju Alluri

      14.1 Introduction 367

      14.2 Cognitive Computing Framework in Healthcare 371

      14.3 Benefits of Using Cognitive Computing for Healthcare 372

      14.4 Applications of Deploying Cognitive Assisted Technology in Healthcare Management 374

      14.4.1 Using Cognitive Services for a Patient’s Healthcare Management 375

      14.4.2 Using Cognitive Services for Healthcare Providers 376

      14.5 Challenges in Using the Cognitive Assistive Technology in Healthcare Management 377

      14.6 Future Directions for Extending Heathcare Services Using CATs 380

      14.7 Addressing CAT Challenges in Healthcare as a General Framework 384

      14.8 Conclusion 384

      References 385

      Index 391

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