Description

Book Synopsis

Many new drugs on the market are chiral compounds, that is, they can exist in two non-superimposable mirror-image forms. Asymmetric catalysis encompasses a large variety of processes for obtaining such compounds. The performance of the catalyst in those processes largely depends on the ligand that makes up the catalyst. This book describes the most relevant ligand libraries for some key processes, including an overview of the state of art and the key mechanistic aspects that favor a high catalytic performance.

Key Features:

  • The book presents historical content from the time of discovery for each family of ligands.
  • Provides a description of the synthetic route and the ligand library's application in various catalytic asymmetric reactions
  • Suitable as supplementary reading for courses targeting the design, synthesis and application of chiral catalysts, asymmetric catalysis and sustainable production
  • Edited by a distinguished scientist in the

Chiral Ligands

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    A Paperback by Montserrat Diéguez

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      Book details

      Publisher CRC Press
      Published 5/27/2024
      ISBN-13 9780367761707
      978-0367761707
      ISBN-10 036776170X
      Also in:
      Pharmacology

      Description

      Book Synopsis

      Many new drugs on the market are chiral compounds, that is, they can exist in two non-superimposable mirror-image forms. Asymmetric catalysis encompasses a large variety of processes for obtaining such compounds. The performance of the catalyst in those processes largely depends on the ligand that makes up the catalyst. This book describes the most relevant ligand libraries for some key processes, including an overview of the state of art and the key mechanistic aspects that favor a high catalytic performance.

      Key Features:

      • The book presents historical content from the time of discovery for each family of ligands.
      • Provides a description of the synthetic route and the ligand library's application in various catalytic asymmetric reactions
      • Suitable as supplementary reading for courses targeting the design, synthesis and application of chiral catalysts, asymmetric catalysis and sustainable production
      • Edited by a distinguished scientist in the

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