Description

Book Synopsis
Provides a sound theoretical basis for understanding chemical kinetics and its uses in studying drug stability. Treats the calculations, approximations, and estimates that are useful to the pharmacist in professional practice, and presents a collection of selected drug-stability data from the pharmaceutical literature. This Handbook makes accessible to the pharmacist much of the information necessary to make pharmaceutical decisions about drug stability. Changes in this edition include thorough revision of the chapter on oxidation, addition of a new chapter on solid-state stability, and a tripling of the number of stability monographs. All monographs figures have been redrawn, most of them from published data, and all sources are cited.

Table of Contents
PRINCIPLES.

Stability Calculations.

Interpretation of Kinetic Data.

Hydrolysis and Other Acyl Transfers.

Oxidation and Photolysis.

Solid-State Chemical Decompostion.

Strategy and Tactics of Stability Testing.

STABILITY MONOGRAPHS.

Appendixes.

Index.

Chemical Stability of Pharmaceuticals

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    A Hardback by Kenneth A. Connors, Gordon L. Amidon, Valentino J. Stella

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      Publisher: John Wiley & Sons Inc
      Publication Date: Publication Date: 19/11/1986
      ISBN13: 9780471879558, 978-0471879558
      ISBN10: 047187955X
      Also in:
      Pharmacology Chemistry

      Description

      Book Synopsis
      Provides a sound theoretical basis for understanding chemical kinetics and its uses in studying drug stability. Treats the calculations, approximations, and estimates that are useful to the pharmacist in professional practice, and presents a collection of selected drug-stability data from the pharmaceutical literature. This Handbook makes accessible to the pharmacist much of the information necessary to make pharmaceutical decisions about drug stability. Changes in this edition include thorough revision of the chapter on oxidation, addition of a new chapter on solid-state stability, and a tripling of the number of stability monographs. All monographs figures have been redrawn, most of them from published data, and all sources are cited.

      Table of Contents
      PRINCIPLES.

      Stability Calculations.

      Interpretation of Kinetic Data.

      Hydrolysis and Other Acyl Transfers.

      Oxidation and Photolysis.

      Solid-State Chemical Decompostion.

      Strategy and Tactics of Stability Testing.

      STABILITY MONOGRAPHS.

      Appendixes.

      Index.

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