Description

Book Synopsis


Table of Contents

List of Contributors xiv

Foreword xvii

Preface xviii

Part I Knowledge for Practice 1

1 Mechanics of the Cardiovascular System 3
Brendan Greaney and Angela M. Kucia

Overview 3

Basic Heart Anatomy 3

References 11

2 Regulation of Cardiac and Vascular Function 12
Brendan Greaney and Angela M. Kucia

Overview 12

Central Nervous System Regulation of the Cardiovascular System 12

Vasomotor Control 14

Baroreceptors 14

Gravity and Venous Return 14

Chemoreceptors 15

Humoral Control 16

Electrolytes 18

Conclusion 19

References 20

3 Cardiac Electrophysiology 21
Brendan Greaney and Angela M. Kucia

Overview 21

Cardiac Cells 21

The Action Potential 22

The Action Potential in Non-Pacemaker Cells 22

The Cardiac Conduction System 24

The Electrocardiogram 26

Conclusion 26

References 28

4 The Coronary Circulation 29
Brendan Greaney and Angela M. Kucia

Overview 29

The Coronary Circulation 29

The Left Main Coronary Artery 30

The Left Anterior Descending Artery 31

The Left Circumflex Artery 31

The Right Coronary Artery 31

Collateral Circulation 32

Microvascular Circulation 32

Coronary Venous Circulation 32

References 33

Part II Cardiovascular Disease Assessment 35

5 Risk Factors for Cardiovascular Disease 37
Angela M. Kucia and Angela Hartley

Overview 37

Absolute Risk 37

Classification of Risk Factors for CVD 38

Biomedical Risk Factors 39

Behavioural Risk Factors 44

Psychosocial Risk Factors 46

Conclusion 48

References 49

6 Cardiovascular Assessment 52
Jan Keenan and Angela M. Kucia

Overview 52

Health History 53

Physical Examination 54

Conclusion 65

References 66

7 Laboratory Tests Used in Acute Cardiac Assessment 67
David Barrett and Angela M. Kucia

Overview 67

Generic Laboratory Tests 67

Common Laboratory Tests Used in Cardiovascular Disease 67

Laboratory Specimen Collection 73

Conclusion 74

References 74

8 Diagnostic Procedures 76
Steven A. Unger and Angela M. Kucia

Overview 76

Purpose of Diagnostic Tests 76

Preparation for Diagnostic Procedures 77

Medical Imaging Tests 78

Electrocardiography Tests 93

Physiological Testing 93

Stress Testing 95

Conclusion 100

References 100

Part III Detection and Management of Heart Rhythm Disturbances 103

9 Electrocardiogram (ECG) Interpretation 105
Carol Oldroyd and Angela M. Kucia

Overview 105

Normal Sequence of Depolarisation and Repolarisation 106

Theoretical Basis of Electrocardiography 107

ECG Leads 107

The Cardiac Axis 110

Determination of Heart Rate and Electrocardiographic Intervals 111

Chamber Enlargement 112

Bundle Branch Block 114

ECG Changes Related to Myocardial Ischaemia and Infarction 117

Myocardial Infarction 118

The ST-Segment 118

Pericarditis 118

Key Point 119

T-Wave Abnormalities 120

Q-Waves 120

Site of Infarction 121

Incremental ECG Leads 121

Obtaining a 12-Lead ECG 122

Equipment Preparation 122

Patient Preparation 123

Conclusion 125

References 126

10 Cardiac Monitoring in the Clinical Setting 128
Angela M. Kucia and Carol Oldroyd

Overview 128

ECG Monitoring Systems and Lead Formats 129

Three-Electrode Monitoring Systems 129

Five-Electrode Monitoring Systems 129

Twelve-Lead (10 Electrode) Monitoring Systems 130

Telemetry Monitoring Systems 131

Indications for Arrhythmia Monitoring in the Clinical Setting 132

Alarm Fatigue 134

References 138

11 Arrhythmias 139
Angela M. Kucia

Overview 139

Mechanisms of Arrhythmia Generation 139

Ectopy, Aberrancy and Escape Beats 145

Sinus Dysrhythmias 147

Atrial Dysrhythmias 150

Ventricular Rhythms and Tachyarrhythmias 156

Heart Block Related to Atrioventricular Nodal Conduction 162

Conclusion 169

References 170

12 Assessment and Management of Cardiac Rhythm Disturbances (Arrhythmias) 173
Carolyn E. Shepherd, Jenny Tagney, and Angela M. Kucia

Overview 173

Assessment 173

Taking a Clinical History 174

Physical Examination 174

Diagnostic Investigations 177

Smartphone Technology 180

Imaging 180

Diagnosis of Cardiac Channelopathies 182

Treatment Strategies for Arrhythmia 183

Pharmacological Therapy 183

Electrical (Direct Current) Synchronised Cardioversion 187

Defibrillation 188

Cardiac Ablation 189

Temporary Pacing 190

Temporary Transvenous Pacing 190

Transcutaneous Pacing 190

Other Forms of Temporary Pacing 191

Implantable Cardiac Devices 191

Implantable Pacemakers 191

Implantable Cardioverter Defibrillators 193

Implantation Procedure for Cardiac Devices 194

Implantable Device Complications 196

Practical Advice for Patients Following Device Implantation 197

Advanced Nursing Roles in Arrhythmia Management 199

References 199

Part IV Detection and Management of Acute Coronary Syndromes 205

13 Pathogenesis of Acute Coronary Syndromes 207
Angela M. Kucia and John D. Horowitz

Overview 207

Acute Coronary Syndrome 207

Atherosclerosis 208

Endothelial Dysfunction 208

Inflammation 208

Plaque Rupture and Thrombosis 209

Pathological Characteristics of Myocardial Ischaemia and Infarction 210

Conclusion 213

References 214

14 Chest Pain Assessment 216
Angela M. Kucia, John F. Beltrame, and Jan Keenan

Overview 216

Background 216

Coronary Heart Disease 217

Angina Pectoris 217

Acute Coronary Syndrome 218

Myocardial Infarction with Non-Obstructive Coronaries (MINOCA) 220

Presentation with Chest Pain in the Emergency Department 220

Typical Clinical Presentation of Ischaemic Chest Pain 221

Atypical Presentations 222

Chest Pain Assessment 223

Physical Examination in ACS Patients 225

The 12‑lead Electrocardiogram in ACS 225

Troponin 227

Clinical Assessment and Risk Stratification in ACS 227

Conclusion 228

References 228

15 Risk Stratification in Acute Coronary Syndromes 231
Deborah Wright, Cassandra Ryan, and Angela M. Kucia

Overview 231

Background 231

The Nature of Risk in Cardiovascular Disease 233

Risk Stratification for Differentiating Between Likely Cardiac-Related Pain and Non-Cardiac Pain 233

Risk Stratification Tools 235

The HEART Score 235

Rule-in/Rule-out Strategies for NSTE-ACS 236

Conclusion 237

References 238

16 Management of Acute Coronary Syndromes 240
Christopher J. Zeitz, Ian D. Jones, and Angela M. Kucia

Overview 240

Background 240

Considerations in Nursing Care of the Patient with Acute Coronary Syndrome 241

ST Elevation Acute Coronary Syndrome (STE-ACS) 242

ST-segment Myocardial Infarction (STEMI) 242

Ischaemic ECG Abnormalities not Meeting STEMI Criteria 245

Cardiac Biomarkers in STEMI 245

Principles of Reperfusion Strategies 245

Mechanical Reperfusion 246

Role of the Nurse when Caring for a Patient Receiving Thrombolysis 248

Complications of STEMI 249

Non-ST-segment Elevation Acute Coronary Syndrome (NSTE-ACS) 252

Convalescence and Secondary Prevention 253

Conclusion 254

References 255

17 Discharge Planning and Convalescence 257
David R. Thompson, Patricia M. Davidson, and Rosemary A. Webster

Overview 257

Hospitalisation 257

Patient and Partner Reactions and Needs after an Acute Cardiac Event 258

Discharge Planning 258

High-Risk Groups 260

Convalescence 261

Promoting Self-Care and Self-Management in the Convalescent Phase 263

Common Concerns of Partners and Family Members 265

Facilitating Convalescence 265

Home-Based Services 266

Nurse-Led Clinics 266

Community Health Workers 266

Information Technology 267

Nursing Strategies to Promote Convalescence 267

Palliative Care 267

Conclusion 267

References 268

18 Prevention Strategies in Cardiovascular Disease 272
Rosemary A. Webster, Patricia M. Davidson, Praba Rabasse, and Angela M. Kucia

Overview 272

Prevention Strategies 272

Primary Prevention in Cardiovascular Disease 273

Secondary Prevention in Cardiovascular Disease 273

Target Population for Secondary Prevention 274

Cardiac Rehabilitation 274

Assessment and Short-Term Monitoring 276

Lifestyle/Behavioural Modification 276

Psychosocial Risk Factors 283

Medication Adherence 283

Recovery and Longer-Term Maintenance 284

Conclusion 285

References 285

Part V Cardiac Arrest 289

19 Sudden Cardiac Death 291
Pete Gregory and Angela M. Kucia

Overview 291

Background 292

Burden of Disease 292

Risk Factors for Sudden Cardiac Death 293

Screening in the General Population for Risk of Sudden Cardiac Death 294

Mechanisms of Sudden Cardiac Death 294

Sudden Cardiac Death in Structural Heart Disease 296

Cardiomyopathies and Sudden Cardiac Death 297

Inherited Primary Arrhythmia Syndromes 298

Sudden Cardiac Death Related to Special Populations 300

Impact of Sudden Cardiac Death on Families and Loved Ones 300

Conclusion 303

References 303

20 Pre-hospital Management of Cardiac Emergencies 306
Pete Gregory and Angela M. Kucia

Overview 306

Introduction 307

Hazards to the Victim and Rescuer 308

Scene Safety 308

Risks to the Rescuer 308

Resuscitation During the COVID-19 Pandemic 308

Risks to the Victim 309

Circumstances that make OHCA Different from Hospital Resuscitation 310

Pauses in Chest Compressions 312

Automated External Defibrillation 312

Practical Factors Affecting Defibrillation 312

Chest Compressions Following Defibrillation 313

Conclusion 313

References 314

21 In-Hospital Resuscitation 317
Angela M. Kucia and Melanie Rushton

Overview 317

Prevention: Systems for Identifying Patients at Risk of Cardiac Arrest 319

Recommended Strategies for the Prevention of Avoidable Cardiac Arrest 320

Rescuer Safety 323

Equipment 325

Basic Life Support 325

Advanced Life Support 326

Post-Resuscitation Care 327

Audit and Data Collection 328

Conclusion 328

References 329

22 Ethical Issues in Resuscitation and end of Life Care 332
Angela M. Kucia and Annabella S. Gloster

Overview 332

Guiding Ethical Principles in Resuscitation 332

Medical Futility 333

Resuscitation Orders 334

Advanced Care Planning and Advanced Directives 335

Withdrawal of Treatment 336

Witnessed Resuscitation 337

Organ Donation 337

Training and Research with the Newly Dead 338

Conclusion 338

References 339

Part VI Chronic Cardiac Conditions 341

23 Heart Failure 343
Salimah Hassan, Christopher Nicholson, Robyn Lotto, and Angela M. Kucia

Overview 343

Definition of Heart Failure 344

Heart Failure Terminology 344

Epidemiology 346

Significance 347

Prognosis 347

Aetiology 347

Diagnosis 348

Investigations 353

Chronic Heart Failure Management 354

Comorbidities in Heart Failure 361

Systems of Care 364

End of Life 365

Acute Heart Failure 365

Conclusion 367

References 367

24 Congenital Heart Disease 372
Robyn Lotto, Christopher Nicholson, and Angela M. Kucia

Overview 372

Background 372

Epidemiology 372

Risk Factors for the Development of Congenital Heart Disease 373

Embryology 374

Congenital Heart Disease Classification 375

CHD with Shunt Between Systemic and Pulmonary Circulation 376

Acyanotic CHD 378

Acyanotic CHD with Outflow Obstruction 381

Cyanotic CHD 383

Dextrocardia 386

Conclusion 393

References 394

25 Structural Heart Disease 399
Christopher Nicholson, Salimah Hassan, Robyn Lotto, and Angela M. Kucia

Overview 399

Valvular Heart Disease 399

Cardiomyopathy 404

Other Forms of Cardiomyopathy 407

The Multidisciplinary Team Caring for Patients with Acquired Structural Heart Disease 408

Conclusion 408

References 409

26 Takotsubo Syndrome 412
Angela M. Kucia

Overview 412

Background 412

Epidemiology 413

Prognosis 413

Pathophysiology 415

Triggers for TTS 416

Clinical Presentation 417

Wall Motion Abnormalities in TTS 419

Cardiac Biomarkers 420

Diagnostic Criteria 420

Diagnostic Imaging 420

Clinical Course 421

Management 422

Conclusion 423

References 424

27 Non-Obstructive Coronary Artery Disease (MINOCA/INOCA) 428
Angela M. Kucia and John F. Beltrame

Overview 428

Myocardial Infarction with Non-Obstructive Coronary Arteries (MINOCA) 428

Management 430

Conclusion 434

References 435

Index 437

Cardiac Care

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    A Paperback / softback by Angela M. Kucia, Ian D. Jones

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      View other formats and editions of Cardiac Care by Angela M. Kucia

      Publisher: John Wiley and Sons Ltd
      Publication Date: 29/09/2022
      ISBN13: 9781119117780, 978-1119117780
      ISBN10: 111911778X

      Description

      Book Synopsis


      Table of Contents

      List of Contributors xiv

      Foreword xvii

      Preface xviii

      Part I Knowledge for Practice 1

      1 Mechanics of the Cardiovascular System 3
      Brendan Greaney and Angela M. Kucia

      Overview 3

      Basic Heart Anatomy 3

      References 11

      2 Regulation of Cardiac and Vascular Function 12
      Brendan Greaney and Angela M. Kucia

      Overview 12

      Central Nervous System Regulation of the Cardiovascular System 12

      Vasomotor Control 14

      Baroreceptors 14

      Gravity and Venous Return 14

      Chemoreceptors 15

      Humoral Control 16

      Electrolytes 18

      Conclusion 19

      References 20

      3 Cardiac Electrophysiology 21
      Brendan Greaney and Angela M. Kucia

      Overview 21

      Cardiac Cells 21

      The Action Potential 22

      The Action Potential in Non-Pacemaker Cells 22

      The Cardiac Conduction System 24

      The Electrocardiogram 26

      Conclusion 26

      References 28

      4 The Coronary Circulation 29
      Brendan Greaney and Angela M. Kucia

      Overview 29

      The Coronary Circulation 29

      The Left Main Coronary Artery 30

      The Left Anterior Descending Artery 31

      The Left Circumflex Artery 31

      The Right Coronary Artery 31

      Collateral Circulation 32

      Microvascular Circulation 32

      Coronary Venous Circulation 32

      References 33

      Part II Cardiovascular Disease Assessment 35

      5 Risk Factors for Cardiovascular Disease 37
      Angela M. Kucia and Angela Hartley

      Overview 37

      Absolute Risk 37

      Classification of Risk Factors for CVD 38

      Biomedical Risk Factors 39

      Behavioural Risk Factors 44

      Psychosocial Risk Factors 46

      Conclusion 48

      References 49

      6 Cardiovascular Assessment 52
      Jan Keenan and Angela M. Kucia

      Overview 52

      Health History 53

      Physical Examination 54

      Conclusion 65

      References 66

      7 Laboratory Tests Used in Acute Cardiac Assessment 67
      David Barrett and Angela M. Kucia

      Overview 67

      Generic Laboratory Tests 67

      Common Laboratory Tests Used in Cardiovascular Disease 67

      Laboratory Specimen Collection 73

      Conclusion 74

      References 74

      8 Diagnostic Procedures 76
      Steven A. Unger and Angela M. Kucia

      Overview 76

      Purpose of Diagnostic Tests 76

      Preparation for Diagnostic Procedures 77

      Medical Imaging Tests 78

      Electrocardiography Tests 93

      Physiological Testing 93

      Stress Testing 95

      Conclusion 100

      References 100

      Part III Detection and Management of Heart Rhythm Disturbances 103

      9 Electrocardiogram (ECG) Interpretation 105
      Carol Oldroyd and Angela M. Kucia

      Overview 105

      Normal Sequence of Depolarisation and Repolarisation 106

      Theoretical Basis of Electrocardiography 107

      ECG Leads 107

      The Cardiac Axis 110

      Determination of Heart Rate and Electrocardiographic Intervals 111

      Chamber Enlargement 112

      Bundle Branch Block 114

      ECG Changes Related to Myocardial Ischaemia and Infarction 117

      Myocardial Infarction 118

      The ST-Segment 118

      Pericarditis 118

      Key Point 119

      T-Wave Abnormalities 120

      Q-Waves 120

      Site of Infarction 121

      Incremental ECG Leads 121

      Obtaining a 12-Lead ECG 122

      Equipment Preparation 122

      Patient Preparation 123

      Conclusion 125

      References 126

      10 Cardiac Monitoring in the Clinical Setting 128
      Angela M. Kucia and Carol Oldroyd

      Overview 128

      ECG Monitoring Systems and Lead Formats 129

      Three-Electrode Monitoring Systems 129

      Five-Electrode Monitoring Systems 129

      Twelve-Lead (10 Electrode) Monitoring Systems 130

      Telemetry Monitoring Systems 131

      Indications for Arrhythmia Monitoring in the Clinical Setting 132

      Alarm Fatigue 134

      References 138

      11 Arrhythmias 139
      Angela M. Kucia

      Overview 139

      Mechanisms of Arrhythmia Generation 139

      Ectopy, Aberrancy and Escape Beats 145

      Sinus Dysrhythmias 147

      Atrial Dysrhythmias 150

      Ventricular Rhythms and Tachyarrhythmias 156

      Heart Block Related to Atrioventricular Nodal Conduction 162

      Conclusion 169

      References 170

      12 Assessment and Management of Cardiac Rhythm Disturbances (Arrhythmias) 173
      Carolyn E. Shepherd, Jenny Tagney, and Angela M. Kucia

      Overview 173

      Assessment 173

      Taking a Clinical History 174

      Physical Examination 174

      Diagnostic Investigations 177

      Smartphone Technology 180

      Imaging 180

      Diagnosis of Cardiac Channelopathies 182

      Treatment Strategies for Arrhythmia 183

      Pharmacological Therapy 183

      Electrical (Direct Current) Synchronised Cardioversion 187

      Defibrillation 188

      Cardiac Ablation 189

      Temporary Pacing 190

      Temporary Transvenous Pacing 190

      Transcutaneous Pacing 190

      Other Forms of Temporary Pacing 191

      Implantable Cardiac Devices 191

      Implantable Pacemakers 191

      Implantable Cardioverter Defibrillators 193

      Implantation Procedure for Cardiac Devices 194

      Implantable Device Complications 196

      Practical Advice for Patients Following Device Implantation 197

      Advanced Nursing Roles in Arrhythmia Management 199

      References 199

      Part IV Detection and Management of Acute Coronary Syndromes 205

      13 Pathogenesis of Acute Coronary Syndromes 207
      Angela M. Kucia and John D. Horowitz

      Overview 207

      Acute Coronary Syndrome 207

      Atherosclerosis 208

      Endothelial Dysfunction 208

      Inflammation 208

      Plaque Rupture and Thrombosis 209

      Pathological Characteristics of Myocardial Ischaemia and Infarction 210

      Conclusion 213

      References 214

      14 Chest Pain Assessment 216
      Angela M. Kucia, John F. Beltrame, and Jan Keenan

      Overview 216

      Background 216

      Coronary Heart Disease 217

      Angina Pectoris 217

      Acute Coronary Syndrome 218

      Myocardial Infarction with Non-Obstructive Coronaries (MINOCA) 220

      Presentation with Chest Pain in the Emergency Department 220

      Typical Clinical Presentation of Ischaemic Chest Pain 221

      Atypical Presentations 222

      Chest Pain Assessment 223

      Physical Examination in ACS Patients 225

      The 12‑lead Electrocardiogram in ACS 225

      Troponin 227

      Clinical Assessment and Risk Stratification in ACS 227

      Conclusion 228

      References 228

      15 Risk Stratification in Acute Coronary Syndromes 231
      Deborah Wright, Cassandra Ryan, and Angela M. Kucia

      Overview 231

      Background 231

      The Nature of Risk in Cardiovascular Disease 233

      Risk Stratification for Differentiating Between Likely Cardiac-Related Pain and Non-Cardiac Pain 233

      Risk Stratification Tools 235

      The HEART Score 235

      Rule-in/Rule-out Strategies for NSTE-ACS 236

      Conclusion 237

      References 238

      16 Management of Acute Coronary Syndromes 240
      Christopher J. Zeitz, Ian D. Jones, and Angela M. Kucia

      Overview 240

      Background 240

      Considerations in Nursing Care of the Patient with Acute Coronary Syndrome 241

      ST Elevation Acute Coronary Syndrome (STE-ACS) 242

      ST-segment Myocardial Infarction (STEMI) 242

      Ischaemic ECG Abnormalities not Meeting STEMI Criteria 245

      Cardiac Biomarkers in STEMI 245

      Principles of Reperfusion Strategies 245

      Mechanical Reperfusion 246

      Role of the Nurse when Caring for a Patient Receiving Thrombolysis 248

      Complications of STEMI 249

      Non-ST-segment Elevation Acute Coronary Syndrome (NSTE-ACS) 252

      Convalescence and Secondary Prevention 253

      Conclusion 254

      References 255

      17 Discharge Planning and Convalescence 257
      David R. Thompson, Patricia M. Davidson, and Rosemary A. Webster

      Overview 257

      Hospitalisation 257

      Patient and Partner Reactions and Needs after an Acute Cardiac Event 258

      Discharge Planning 258

      High-Risk Groups 260

      Convalescence 261

      Promoting Self-Care and Self-Management in the Convalescent Phase 263

      Common Concerns of Partners and Family Members 265

      Facilitating Convalescence 265

      Home-Based Services 266

      Nurse-Led Clinics 266

      Community Health Workers 266

      Information Technology 267

      Nursing Strategies to Promote Convalescence 267

      Palliative Care 267

      Conclusion 267

      References 268

      18 Prevention Strategies in Cardiovascular Disease 272
      Rosemary A. Webster, Patricia M. Davidson, Praba Rabasse, and Angela M. Kucia

      Overview 272

      Prevention Strategies 272

      Primary Prevention in Cardiovascular Disease 273

      Secondary Prevention in Cardiovascular Disease 273

      Target Population for Secondary Prevention 274

      Cardiac Rehabilitation 274

      Assessment and Short-Term Monitoring 276

      Lifestyle/Behavioural Modification 276

      Psychosocial Risk Factors 283

      Medication Adherence 283

      Recovery and Longer-Term Maintenance 284

      Conclusion 285

      References 285

      Part V Cardiac Arrest 289

      19 Sudden Cardiac Death 291
      Pete Gregory and Angela M. Kucia

      Overview 291

      Background 292

      Burden of Disease 292

      Risk Factors for Sudden Cardiac Death 293

      Screening in the General Population for Risk of Sudden Cardiac Death 294

      Mechanisms of Sudden Cardiac Death 294

      Sudden Cardiac Death in Structural Heart Disease 296

      Cardiomyopathies and Sudden Cardiac Death 297

      Inherited Primary Arrhythmia Syndromes 298

      Sudden Cardiac Death Related to Special Populations 300

      Impact of Sudden Cardiac Death on Families and Loved Ones 300

      Conclusion 303

      References 303

      20 Pre-hospital Management of Cardiac Emergencies 306
      Pete Gregory and Angela M. Kucia

      Overview 306

      Introduction 307

      Hazards to the Victim and Rescuer 308

      Scene Safety 308

      Risks to the Rescuer 308

      Resuscitation During the COVID-19 Pandemic 308

      Risks to the Victim 309

      Circumstances that make OHCA Different from Hospital Resuscitation 310

      Pauses in Chest Compressions 312

      Automated External Defibrillation 312

      Practical Factors Affecting Defibrillation 312

      Chest Compressions Following Defibrillation 313

      Conclusion 313

      References 314

      21 In-Hospital Resuscitation 317
      Angela M. Kucia and Melanie Rushton

      Overview 317

      Prevention: Systems for Identifying Patients at Risk of Cardiac Arrest 319

      Recommended Strategies for the Prevention of Avoidable Cardiac Arrest 320

      Rescuer Safety 323

      Equipment 325

      Basic Life Support 325

      Advanced Life Support 326

      Post-Resuscitation Care 327

      Audit and Data Collection 328

      Conclusion 328

      References 329

      22 Ethical Issues in Resuscitation and end of Life Care 332
      Angela M. Kucia and Annabella S. Gloster

      Overview 332

      Guiding Ethical Principles in Resuscitation 332

      Medical Futility 333

      Resuscitation Orders 334

      Advanced Care Planning and Advanced Directives 335

      Withdrawal of Treatment 336

      Witnessed Resuscitation 337

      Organ Donation 337

      Training and Research with the Newly Dead 338

      Conclusion 338

      References 339

      Part VI Chronic Cardiac Conditions 341

      23 Heart Failure 343
      Salimah Hassan, Christopher Nicholson, Robyn Lotto, and Angela M. Kucia

      Overview 343

      Definition of Heart Failure 344

      Heart Failure Terminology 344

      Epidemiology 346

      Significance 347

      Prognosis 347

      Aetiology 347

      Diagnosis 348

      Investigations 353

      Chronic Heart Failure Management 354

      Comorbidities in Heart Failure 361

      Systems of Care 364

      End of Life 365

      Acute Heart Failure 365

      Conclusion 367

      References 367

      24 Congenital Heart Disease 372
      Robyn Lotto, Christopher Nicholson, and Angela M. Kucia

      Overview 372

      Background 372

      Epidemiology 372

      Risk Factors for the Development of Congenital Heart Disease 373

      Embryology 374

      Congenital Heart Disease Classification 375

      CHD with Shunt Between Systemic and Pulmonary Circulation 376

      Acyanotic CHD 378

      Acyanotic CHD with Outflow Obstruction 381

      Cyanotic CHD 383

      Dextrocardia 386

      Conclusion 393

      References 394

      25 Structural Heart Disease 399
      Christopher Nicholson, Salimah Hassan, Robyn Lotto, and Angela M. Kucia

      Overview 399

      Valvular Heart Disease 399

      Cardiomyopathy 404

      Other Forms of Cardiomyopathy 407

      The Multidisciplinary Team Caring for Patients with Acquired Structural Heart Disease 408

      Conclusion 408

      References 409

      26 Takotsubo Syndrome 412
      Angela M. Kucia

      Overview 412

      Background 412

      Epidemiology 413

      Prognosis 413

      Pathophysiology 415

      Triggers for TTS 416

      Clinical Presentation 417

      Wall Motion Abnormalities in TTS 419

      Cardiac Biomarkers 420

      Diagnostic Criteria 420

      Diagnostic Imaging 420

      Clinical Course 421

      Management 422

      Conclusion 423

      References 424

      27 Non-Obstructive Coronary Artery Disease (MINOCA/INOCA) 428
      Angela M. Kucia and John F. Beltrame

      Overview 428

      Myocardial Infarction with Non-Obstructive Coronary Arteries (MINOCA) 428

      Management 430

      Conclusion 434

      References 435

      Index 437

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