Description
Book SynopsisA comprehensive text in the field of biomaterials science and tissue engineering, covering fundamental principles and methods related to processing-microstructure-property linkages as applied to biomaterials science. Essential concepts and techniques of the cell biology are discussed in detail, with a focus quantitatively and qualitatively evaluating cell-material interaction. It gives detailed discussion on the processing, structure and properties of metals, ceramics and polymers, together with techniques and guidelines. Comprehensive coverage of in vitro and in vivo biocompatibility property evaluation of materials for bone, neural as well as cardiovascular tissue engineering applications, together with representative protocols. Supported by several multiple-choice questions, fill in the blanks, review questions, numerical problems and solutions to selected problems, this is an ideal text for undergraduate and graduate students in understanding fundamental concepts and the latest dev
Trade Review'This book emphasizes the fundamentals of both Materials and Biological Sciences. On the Materials science front, it contains chapters which provide non-specialists with a fundamental understanding on the conventional and advanced manufacturing techniques as well as mechanical properties. Clearly, the strength of this textbook lies in the clear description of the in vitro and in vivo biocompatibility assessment protocols, an asset for non-biologists. The conclusion presents a number of chapters describing case studies, primarily from the author's own research. The number of problem sets and assignments are also important attributes.' Cato T. Laurencin, Chief Executive Officer, Connecticut Institute for Clinical and Translational Science, University of Connecticut
'The book is extremely well structured and every chapter is critical for anyone planning to design medical devices or implants. For example, the inclusion of a chapter on biofilms is a wonderful addition and you will not normally find this in a biomaterials text. For the last thirty years I have been teaching graduate level materials science both in the US and India. This would be a book I would make a mandatory course reference, as I have wanted to include more biological considerations into the standard materials science course.' Shantikumar Nair, Director, Center for Nanosciences, Amrita Vishwa Vidyapeetham University Kochi, India
Table of ContentsForeword I; Foreword II; Preface; Section I. Overview: 1. Introduction; 2. Materials for Biomedical Applications; 3. Tissue Engineering Scaffolds: Principles and Properties; Section II. Fundamentals – Materials Science: 4. Conventional and Advanced Manufacturing of Biomaterials; 5. Probing Structure of Materials at Multiple Length Scales; 6. Mechanical Properties: Principles and Assessment; Section III. Fundamentals – Biological Science: 7. Cells, Proteins and Nucleic Acids: Structure and Properties; 8. Cell-Material Interaction and Biocompatibility; 9. Probing Cell Response, in vitro; 10. Bacterial Growth and Biofilm Formation; 11. Probing Tissue Response, in vivo; Section IV. Illustrative Examples of Biomaterials Development: 12. Case Study: Corrosion and Wear of Selected Ti-alloys; 13. Case Study: Calcium Phosphate–Mullite Composites; 14. Case Study: Compression Moulded HDPE-based Hybrid Biocomposites; 15. Case Study: Phase Stability, Bactericidal and Cytocompatibility of HA–Ag; 16. Case Study: HA-CaTiO3 based Multifunctional Composites; 17. Case Study: Compatibility of Neuronal/Cardiac Cells with Patterned Substrates; 18. Perspectives; Appendix A; Appendix B; References; Index; Colour Plates.
