Description
Book SynopsisCardiovascular disease (CVD) is the leading cause of morbidity and mortality in women and men worldwide and represents a major financial burden to world health care systems. Importantly, CVD has eclipsed cancer as the leading cause of death for women globally. Through advancements in research and clinical testing, the symptoms and risk factors for CVD have been well established for men, but not for women. Consequently, there is an immediate need for new innovative research that will bridge this gap and allow for improved early diagnosis and treatment of CVD in women. This book will serve as a guide for health care providers to better understand the physiological, biochemical, and genetic differences in heart disease in women with the goal of providing improved education, awareness and treatment of cardiovascular disease in women. The book will cover topics such as: sex dependent clinical outcomes of cardiovascular disease, cardiac protection by estrogen, cardiac health during menopause, cardiac rehabilitation programs, fitness and exercise, cardio-oncology, shift work and the CVD risk, and pregnancy related CVD.
Table of Contents1. Lorrie KirshenbaumInstitute of Cardiovascular Sciences, Departments of Physiology and Pathophysiology, and Pharmacology and Therapeutics, University of Manitoba Winnipeg, Manitoba, CanadaEmail: LKirshenbaum@sbrc.ca Title: Attenuation of Bnip3 Mediated Doxorubicin-Induced Cell Death in Cardiac Myocytes
2. Inna Rabinovich-NikitinInstitute of Cardiovascular Sciences, Department of Physiology and Pathophysiology, University of ManitobaWinnipeg, Manitoba, CanadaEmail: IRabinovich-Nikitin@sbrc.ca Title: Sex Dependent Regulation of Circadian Rhythms in Health and Disease
3. Tami MartinoOntario Veterinary College, Centre for Cardiovascular Investigations, Guelph University Guelph, Ontario, CanadaEmail: tmartino@uoguelph.ca Title: Circadian Pharmacological Approach to Treat Myocardial Infarct
4. Ross FeldmanInstitute of Cardiovascular Sciences, St. Boniface HospitalWinnipeg, Manitoba, CanadaEmail: RFeldman@sbrc.ca Title: GPER Function as a Determinant of the Progression of Atherosclerotic Disease in Women
5. Paula HarveyDepartment of Medicine, Women’s College HospitalToronto, Ontario, CanadaEmail: paula.harvey@wchospital.ca Title: Novel Therapeutic Approach to Treat Cardiac-Rheumatology in Females
6. Moira K. KapralDepartment of Medicine and Institute of Health Policy, Management and Evaluation, University Health Network and Toronto General HospitalToronto, Ontario, CanadaEmail: moira.kapral@uhn.ca Title: Correlation between Sex, Immigration Status, Ethnicity, and Long-term Outcomes of Ischemic Stroke
7. Jodi EdwardsSchool of Epidemiology and Public Health, University of Ottawa Heart InstituteOttawa, Ontario, CanadaEmail: jedwards@ottawaheart.ca Title: Risk Assessment and Predictive Modelling for The Heart-Brain Interface in Women
8. Heather TullochDepartment of Medicine, Faculty of Medicine, University of Ottawa Heart Institute Ottawa, Ontario, CanadaEmail: hetulloch@ottawaheart.ca Title: Insomnia Interventions for Female Cardiac Patients
9. Maurice Enriquez-SaranoAmerican College of Cardiology, Mayo ClinicRochester, Minnesota, United StatesEmail: sarano.maurice@mayo.edu Title: Aortic Stenosis Progression, Cardiac Damage, and Survival: Comparison Between Men and Women
10. Anita AsgarMontreal Heart Institute, Universite de MontrealMontreal, Québec, CanadaEmail: anita.asgar@umontreal.ca Title: Treatment and Management of Valvular Heart Disease and Cost-Effectiveness Analysis
11. Maral OuzounianPeter Munk Cardiac Centre, University Health NetworkToronto, Ontario, CanadaEmail: maral.ouzounian@uhn.ca Title: Association of Mortality and Acute Aortic Events with Ascending Aortic Aneurysm
12. Sharonne HayesDepartment of Cardiovascular Medicine, Mayo ClinicRochester, Minnesota, United StatesEmail: hayes.sharonne@mayo.edu Title: Improving Diagnosis and Treatment for Patients Who Suffer Spontaneous Coronary Artery Dissection (SCAD)
13. Mamas A. MamasInstitute for Primary Care and Health Sciences, Keele UniversityKeele, EnglandEmail: m.mamas@keele.ac.uk Title: Preeclampsia and Future Cardiovascular Health
14. Kara NerenbergDepartment of Medicine, University of CalgaryCalgary, Alberta, CanadaEmail: kara.nerenberg@ucalgary.ca Title: Cardiovascular Disease in Women with a History of Pregnancy Complications
15. Michele TurekDepartment of Medicine, Cumming School of Medicine, University of Ottawa Heart Institute and The Ottawa HospitalOttawa, Ontario, CanadaEmail: mturek@ottawaheart.ca Title: Hormone Replacement Treatment for Cardiovascular Disease
16. Husam Abdel-QadirDepartment of Medicine, Women’s College Hospital and University Health Network Toronto, Ontario, CanadaEmail: husam.abdel-qadir@wchospital.ca Title: Cardiovascular Mortality Following Early-Stage Breast Cancer
17. Erin MichosCiccarone Center for the Prevention of Cardiovascular Disease, Johns Hopkins University School of MedicineBaltimore, Maryland, United StatesEmail: edonnel1@jhmi.edu Title: Lipid Management for the Prevention of Atherosclerotic Cardiovascular Disease in Women
18. Tracey J.F. ColellaKITE Research Institute, University Health NetworkToronto, Ontario, CanadaEmail: tracey.colella@uhn.ca Title: Sex Differences in Cardiac Rehabilitation Enrollment
19. Robert ReidDepartment of Obstetrics and Gynaecology, University of Ottawa Heart InstituteOttawa, Ontario, CanadaEmail: breid@ottawaheart.ca Title: Promoting Exercise and Physical Activity in Female Patients with Heart Disease
20. Karin H. HumphriesCentre for Improved Cardiovascular Health, University of British ColumbiaVancouver, British Columbia, CanadaEmail: khumphries@icvhealth.ubc.ca Title: Sex and Gender Differences in the Diagnosis, Treatment, and Outcomes of Coronary Artery Disease
21. Thais CoutinhoCanadian Women's Heart Health Centre, University of Ottawa Heart InstituteOttawa, Ontario, CanadaEmail: tcoutinho@ottawaheart.caTitle: Sex Differences in Arterial Aging and its Implications on Cardiovascular Diseases
22. Amy West PollakCardiovascular Medicine, Mayo Clinic Jacksonville, Florida, United StatesEmail: pollak.amy@mayo.eduTitle: Impact of a Novel Community-Based Lifestyle Intervention Program on Type 2 Diabetes and Cardiovascular Risk
23. Lisa MielniczukDivision of Cardiology, University of Ottawa Heart InstituteOttawa, Ontario, CanadaEmail: lmielniczuk@ottawaheart.ca Title: Clinical Outcomes Related to Heart Failure and Pulmonary Hypertension
24. Colleen NorrisFaculty of Nursing, University of AlbertaEdmonton, Alberta, CanadaEmail: colleen.norris@ualberta.ca Title: Examination of Health-Related Quality of Life in Women with Coronary Artery Disease
25. Krystina B. LewisFaculty of Health Sciences, University of OttawaOttawa, Ontario, CanadaEmail: klewi3@uottawa.ca Title: The Risks and Benefits of Implantable Cardioverter-Defibrillator Generator Replacement
26. Beth L. AbramsonDivision of Cardiology, St. Michael's Hospital and University of TorontoToronto, Ontario, CanadaEmail: abramsonb@smh.ca Title: The Effects and Roles of Estrogen in Managing Hypertension in Menopausal Women
27. Sharon L. MulvaghDepartment of Cardiovascular Medicine, Mayo ClinicRochester, Minnesota, United StatesEmail: smulvagh@mayo.edu Title: The Effects of Menopausal Hormone Therapy on the Vascular System
28. Tara L. SedlakLeslie Diamond Women's Heart Center, Vancouver General, St. Paul’s, and UBC Hospitals, Vancouver, British Columbia, CanadaEmail: Tara.Sedlak@vch.ca Title: Influence of Sex Differences in Non-Obstructive Coronary Artery Disease
29. Karen ReueDepartment of Human Genetics, University of California at Los Angeles (UCLA)Los Angeles, California, United StatesEmail: reuek@ucla.eduTitle: Diet1 and Resistance to High Cholesterol Levels and Cardiovascular Disease
30. Harriette G.C. Van SpallDepartment of Medicine and Department of Health Research Methods, McMaster UniversityHamilton, Ontario, CanadaEmail: harriette.vanspall@phri.ca Title: Interventions to Improve Clinical Outcomes Following Hospitalization for Heart Failure
31. Shelley ZierothInstitute of Cardiovascular Sciences, Institute of Cardiovascular SciencesWinnipeg, Manitoba, CanadaEmail: SZieroth@sbgh.mb.ca Title: Sex-Dependent Cardioprotective Effects of the Phytoestrogen Resveratrol
32. Mary Norine WalshHeart Failure and Cardiac Transplantation Program, St. Vincent Heart Centre, Indianapolis, Indiana, United StatesEmail: macwalsh@iquest.net Title: Blood Pressure Across a Woman's Life Cycle
33. Martha GulatiDepartment of Medicine, College of Medicine - Phoenix and the University of Arizona Phoenix, Arizona, United StatesEmail: marthagulati@email.arizona.edu Title: Women’s Fitness Levels and Heart Rate Response to Exercise
34. Paul OhCardiovascular Prevention and Rehabilitation Program, University Health Network Toronto, Ontario, CanadaEmail: paul.oh@uhn.ca Title: Supervised Exercise Therapy Through Cardiac Rehabilitation following Peripheral Arterial Disease
35. Delphine BaetzCarMeN Laboratory, Claude Bernard University Lyon 1Lyon, FranceEmail: delphine.baetz@univ-lyon1.frTitle: Sex Differences in ANT2-Mediated ATP Import into Mitochondria for Protection Against Hypoxia Lethal Injury