Description

Book Synopsis
A vital resource on blood and bone marrow cell morphology in laboratory animal medicine. This fully revised new edition is an essential reference for clinical pathologists in diagnostic laboratories, and medical or veterinary research. The atlas contains over 400 color images of cells from the peripheral blood and bone marrow from a variety of animals encountered in laboratory animal medicine, in health and disease.

Key features:

  • New chapter on flow cytometry and its application in terms of routine analyses as a means of identifying abnormalities in cell marker expression, which is of particular relevance for pre-clinical safety assessment
  • Covers the most recent developments in laboratory animal hematology, including parameters measured by the latest generation of analyzers
  • Coverage of a wide range of laboratory animal species, as well as those used in clinical veterinary trials
  • Photomicrographs present normal and abnormal blood cells from a

    Trade Review

    “This book may not be useful for the typical veterinary student or practitioner, but it is an excellent resource for those involved in preclinical studies on toxicosis.” (Journal of The American Veterinary Medical Association, 15 June 2012)

    "A fine college reference!." (The Midwest Book Review, 1 November 2011)

    Table of Contents

    Foreword vii

    Introduction ix

    Dedication xi

    Acknowledgments xiii

    1 Rodents 1

    Mouse 1

    Introduction 1

    Blood picture 1

    Typical ranges (Siemens Advia 120) 2

    Hamster 15

    Introduction 15

    Blood picture 15

    Guinea Pig 17

    Introduction 17

    Blood picture 17

    Rat – Sprague Dawley (SD)/Han Wistar (HW) 18

    Introduction 18

    Blood picture 18

    Typical ranges (Siemens Advia 120) 19

    References 36

    2 Rabbit 37

    Introduction 37

    Blood picture 37

    References 39

    4 Dog 45

    Introduction 45

    Blood picture 45

    Typical ranges (Siemens Advia 120) 46

    References 64

    5 Monkey 65

    Introduction 65

    Blood picture 65

    Marmoset 66

    Cynomolgus 71

    Introduction 71

    Blood picture 71

    Typical ranges (Siemens Advia 120) 72

    Baboon 84

    Rhesus Monkey 86

    References 87

    6 Other species 89

    Pig 89

    Introduction 89

    Blood picture 89

    Horse 91

    Introduction 91

    Blood picture 91

    Goat and Sheep 94

    Assorted Other Species 96

    References 103

    3 Cat 41

    Introduction 41

    Blood picture 41

    References 44

    7 Blood collection procedures 105

    Common bleeding sites 105

    Anticoagulants 105

    Staining 105

    8 Artifacts 107

    Collection artifacts 107

    Sample transport and storage 109

    Anticoagulant 110

    Storage artifacts 111

    Blood smear preparation 113

    Stain precipitate 113

    References 114

    9 Bone marrow 115

    Introduction 115

    Review of marrow sampling techniques 115

    Recommended methods for marrow sampling 116

    Preparation and staining of smears 118

    Evaluation 119

    Interpretation 119

    References 120

    10 Comparative applications in flow cytometry 121

    Application of flow cytometry in comparative hematology 122

    References 132

    Index 135

Atlas of Comparative Diagnostic and Experimental

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Order before 4pm today for delivery by Sat 20 Dec 2025.

A Hardback by Clifford Smith, Alfred Jarecki

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    View other formats and editions of Atlas of Comparative Diagnostic and Experimental by Clifford Smith

    Publisher: John Wiley and Sons Ltd
    Publication Date: 15/07/2011
    ISBN13: 9781405171076, 978-1405171076
    ISBN10: 1405171073

    Description

    Book Synopsis
    A vital resource on blood and bone marrow cell morphology in laboratory animal medicine. This fully revised new edition is an essential reference for clinical pathologists in diagnostic laboratories, and medical or veterinary research. The atlas contains over 400 color images of cells from the peripheral blood and bone marrow from a variety of animals encountered in laboratory animal medicine, in health and disease.

    Key features:

    • New chapter on flow cytometry and its application in terms of routine analyses as a means of identifying abnormalities in cell marker expression, which is of particular relevance for pre-clinical safety assessment
    • Covers the most recent developments in laboratory animal hematology, including parameters measured by the latest generation of analyzers
    • Coverage of a wide range of laboratory animal species, as well as those used in clinical veterinary trials
    • Photomicrographs present normal and abnormal blood cells from a

      Trade Review

      “This book may not be useful for the typical veterinary student or practitioner, but it is an excellent resource for those involved in preclinical studies on toxicosis.” (Journal of The American Veterinary Medical Association, 15 June 2012)

      "A fine college reference!." (The Midwest Book Review, 1 November 2011)

      Table of Contents

      Foreword vii

      Introduction ix

      Dedication xi

      Acknowledgments xiii

      1 Rodents 1

      Mouse 1

      Introduction 1

      Blood picture 1

      Typical ranges (Siemens Advia 120) 2

      Hamster 15

      Introduction 15

      Blood picture 15

      Guinea Pig 17

      Introduction 17

      Blood picture 17

      Rat – Sprague Dawley (SD)/Han Wistar (HW) 18

      Introduction 18

      Blood picture 18

      Typical ranges (Siemens Advia 120) 19

      References 36

      2 Rabbit 37

      Introduction 37

      Blood picture 37

      References 39

      4 Dog 45

      Introduction 45

      Blood picture 45

      Typical ranges (Siemens Advia 120) 46

      References 64

      5 Monkey 65

      Introduction 65

      Blood picture 65

      Marmoset 66

      Cynomolgus 71

      Introduction 71

      Blood picture 71

      Typical ranges (Siemens Advia 120) 72

      Baboon 84

      Rhesus Monkey 86

      References 87

      6 Other species 89

      Pig 89

      Introduction 89

      Blood picture 89

      Horse 91

      Introduction 91

      Blood picture 91

      Goat and Sheep 94

      Assorted Other Species 96

      References 103

      3 Cat 41

      Introduction 41

      Blood picture 41

      References 44

      7 Blood collection procedures 105

      Common bleeding sites 105

      Anticoagulants 105

      Staining 105

      8 Artifacts 107

      Collection artifacts 107

      Sample transport and storage 109

      Anticoagulant 110

      Storage artifacts 111

      Blood smear preparation 113

      Stain precipitate 113

      References 114

      9 Bone marrow 115

      Introduction 115

      Review of marrow sampling techniques 115

      Recommended methods for marrow sampling 116

      Preparation and staining of smears 118

      Evaluation 119

      Interpretation 119

      References 120

      10 Comparative applications in flow cytometry 121

      Application of flow cytometry in comparative hematology 122

      References 132

      Index 135

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