Description
Book Synopsis1 Antibody-Drug Conjugates: A Historical Review.- 2 Payloads of Antibody-Drug Conjugates.- 3 Selecting an Optimal Antibody for Antibody-Drug Conjugate Therapy.- 4 Linker Design for Antibody-Drug Conjugates.- 5 Formulation Development for Antibody-Drug Conjugates.- 6 Bioanalytical Assay for Characterization of Antibody Drug Conjugates.- 7 Pharmacokinetics/Pharmacodynamics and Disposition of Antibody-Drug Conjugates.- 8 Regulatory Considerations.- 9 Major ADC Companies, Current Clinical Trials, Recent Patents Issued and Patent Applications, and Cost Analysis of Drug Therapy.- 10 Mylotarg: Revisiting its Clinical Potential Post-Withdrawal.- 11 ADCETRIS: A Regulatory Case Study of a New Generation Antibody Drug Conjugate.- 12 Ado-Trastuzumab Emtansine.- 13 The Antibody-Drug Conjugate Glembatumumab Vedotin (CDX-011) and its Use in Treatment of Breast Cancer.- 14 Summary and Future Directions.
