Description
Book SynopsisIntroduction to Pain and its relation to Nervous System Disorders provides an accessible overview of the latest developments in the science underpinning pain research, including, but not limited to, the physiological, pathological and psychological aspects.
Table of ContentsList of contributors ix
Foreword xiii
Acknowledgements xv
Notes on authors xvii
Introduction 1
Section I: Neurobiology of pain: Recent advances 11
1 Anatomy of pain pathways 13
Andrew J. Todd
2 Spinal plasticity of the nociceptive system: The role of central sensitization in chronic pain states 35
Alban Latremolière
3 Symptoms and pathology in neuropathic pain 89
Matthew Thakur and Stephen B. McMahon
4 Recent advances in neuroimmune interactions in neuropathic pain: The role of microglia 123
Elizabeth A. Old, Louise S. C. Nicol and Marzia Malcangio
5 Genetics and epigenetics of pain 149
Franziska Denk and Stephen B. McMahon
6 The cannabinoid system and its role in nociception 169
Massimiliano Beltramo
7 EphB receptors and persistent pain 201
Isabella Gavazzi
Section II: Pain in the brain 225
8 Brain imaging in experimental pain 227
Massieh Moayedi and Tim V. Salomons
9 Placebo effects in pain 249
Luana Colloca, Adam P. Horin and Damien Finniss
10 Psychology and pain 267
Lance M. McCracken
Section III: Pain in the lifecycle and in nervous system disorders 281
11 Pain in neonates and infants 283
Fiona Moultrie, Sezgi Goksan, Ravi Poorun and Rebeccah Slater
12 How do people with autism spectrum disorders (ASD) experience pain? 295
Cecile Rattaz, Amandine Dubois and Amaria Baghdadli
13 Pain and depression: The janus factor of human suffering 317
Angela Iannitelli and Paola Tirassa
14 Pain in multiple sclerosis: From classification to treatment 345
Claudio Solaro and Michele Messmer
15 Pain perception in dementia 361
Miriam Kunz and Stefan Lautenbacher
16 The role of cognitive impairment in the placebo and nocebo effects 373
Martina Amanzio
17 An overview of pain in parkinson’s disease 387
Panagiotis Zis, Elisaveta Sokolov and Kallol Ray Chaudhuri
Appendix: Interviews with chronic pain patients 409
Index 000
