Description
Book SynopsisHuman health issues relating to amino acids are extremely broad and include metabolic disorders of amino acid metabolism as well as their presence in food and use as supplements. This book covers the biochemistry of amino acid metabolism in the context of health and disease. It discusses their use as food supplements, in clinical therapy and nutritional support and focuses on major recent developments, highlighting new areas of research that will be needed to sustain further interest in the field.
Table of ContentsPART I: ENZYMES AND METABOLISM 1: Glutamate Dehydrogenase 2: Aminotransferases 3: Arginase 4: Bypassing the Endothelial L-Arginine-Nitric-Oxide Pathway: Effects of Dietary Nitrite and Nitrate on Cardiovascular Function 5: Histidine Decarboxylase 6: Glutamate Decarboxylase 7: Glutaminase 8: D-Serine and Serine Racemase in Retina 9: Tryptophan Hydroxylase 10: Methionine Metabolism PART II: DYNAMICS 11: Amino Acid Transport Across Each Side of the Blood-Brain Barrier 12: Inter-Organ Fluxes of Amino Acids 13: Cellular Adaptation to Amino Acid Availability: Mechanisms Involved in the Regulation of Gene Expression PART III: NUTRITION 14: Endogenous Amino Acids at the Terminal Ileum of the Adult Human 15: Metabolic Availability of Amino Acids in Food Proteins: New Methodology 16: Amino Acid Requirements: Quantitative Estimates 17: Amino Acid Supplements and Muscular Performance 18: Amino Acids in Clinical and Nutritional Support: Glutamine in Duchenne Muscular Dystrophy 19: Adverse Effects 20: The Umami Taste of Glutamate PART IV: HEALTH 21: Homocysteine Status: Factors Affecting and Health Risks 22: Modified Amino Acid-Based Molecules: Accumulation and Health Implications 23: Phenylketonuria: Newborn Identification Through to Adulthood 24: Principles of Rapid Tryptophan Depletion and its use in Research on Neuropsychiatric Disorders 25: Excitatory Amino Acids in Neurological and Neurodegenerative Disorders 26: Efficacy of L-DOPA Therapy in Parkinson's Disease 27: Amino Acid Profiles for Diagnostic Applications PART V: CONCLUSIONS 28: Emergence of a New Momentum
