Description
Book SynopsisA practical, all-inclusive roadmap to understanding and executing advanced surgical research
Advanced Concepts in Surgical Research is a practical, reader-friendly guide to planning, conducting, and evaluating solid, evidence-based surgical research that leads to high-quality results. Geared to the investigator who has already mastered basic principles, this book focuses on more advanced topics such as randomized controlled trials, survey design, observational studies, meta analyses, statistical concepts, reporting of data, and much more.
Special Features:
- Includes tips and insights from experienced surgical researchers on how to conduct an effective clinical study and avoid pitfalls
- Supplies hard-to-find information on current topics such as randomization systems and technology and publication bias
- Provides standardized, easy-to-reference text boxes with highlighted key concepts, on-the-spot definitions of terminology in Jargon Simplified sections, and real-world case examples from the literature
- Presents nearly 60 illustrations and tables to help in visualizing key concepts
Filled with proven research methodologies, clinical data, examples, and strategies that can be applied across a wide range of disciplines, Advanced Concepts in Surgical Research illuminates the challenges and solutions of modern day surgical research. It is essential for any clinician undertaking a well-defined, systematic, clinically relevant, and ultimately successful surgical research study.
Table of Contents1 Factorial Randomized Trials
2 Expertise-Based Randomized Trials
3 Randomization Systems and Technology
4 Blinding and Concealment
5 Composite Outcome in Orthopaedics: Understanding the Concepts
6 Adjudication of Outcomes—Systems and Approaches
7 Subgroup Analyses
8 Trial Management—Advanced Concepts and Systems
9 Case–Control Studies
10 Cohort Studies
11 Survey Design
12 Qualitative Studies
13 Economic Analysis
14 Literature Searches
15 Understanding Effect Sizes
16 Fixed Effects versus Random Effects
17 Heterogeneity
18 Uncovering Publication Bias
19 Statistical Pooling—Programs and Systems
20 Meta-analysis of Observations Studies
21 Meta-regression
22 Preparing a Statistical Analysis Plan
23 Regression Analysis
24 Survival Analysis
25 Interim Analyses in Randomized Trials
26 Conflicts of Interest Reporting
27 Authorship—Modern Approaches and Reporting
28 Randomized Trials Reporting Checklists
29 Observational Studies Reporting Checklists
30 Meta-analysis Reporting Checklists
Resources and Contacts for Surgical Research
Glossary of Terms
