Description

Book Synopsis
  • Provides a comprehensive update on therapies for Parkinson's disease and other movement disorders
  • Describes the basic mechanisms of neurodegeneration, pharmacologic interventions for motor and non-motor symptoms, and surgical management
  • Features summary tables and algorithms that serve as a quick reference guide for practical treatment decisions
  • The expert guidance of recognised authorities will enable readers of this book to plan their patients' care with greater confidence


Trade Review
"This book can be strongly recommended and is an asset to libraries of both movement disorder specialists and general neurologists. Its logical structure, linking therapy with underlying pathophysiology, means that it will remain a useful reference even as new therapies inevitably emerge." (The Lancet Neurology, July 2009)

Table of Contents

Preface ix

Contributors xi

Part I Parkinson’s Disease and Parkinsonism

1 The Etiopathogenesis of Parkinson’s Disease: Basic Mechanisms of Neurodegeneration 3
C. Warren Olanow and Kevin McNaught

2 Physiology of Parkinson’s Disease 25
Shlomo Elias, Zvi Israel and Hagai Bergman

3 Pharmacology of Parkinson’s Disease 37
Jonathan M. Brotchie

4 The Treatment of Early Parkinson’s Disease 49
Olivier Rascol and Regina Katzenschlager

5 Treatment of Motor Complications in Advanced Parkinson’s Disease 71
Susan H. Fox and Anthony E. Lang

6 Managing the Non-Motor Symptoms of Parkinson’s Disease 91
Werner Poewe and Klaus Seppi

7 Surgery for Parkinson’s Disease 121
Jens Volkmann

8 Future Cell- and Gene-Based Therapies for Parkinson’s Disease 145
Tomas Björklund, Asuka Morizane, Deniz Kirik and Patrik Brundin

9 Parkinson-Plus Disorders 157
Martin Köllensperger and Gregor K. Wenning

Part II Tremor Disorders

10 Essential Tremor 179
Rodger J. Elble

11 Other Tremor Disorders 193
Günther Deuschl

Part III Dystonia, Cramps, and Spasms

12 Pathophysiology of Dystonia 205
Mark Hallett

13 General Management Approach to Dystonia 217
Cynthia L. Comella

14 Botulinum Toxin for Treatment of Dystonia 227
Dirk Dressler

15 Surgical Treatments of Dystonia 241
Christopher Kenney and Joseph Jankovic

16 Wilson’s Disease 251
George J. Brewer

17 Cramps and Spasms 263
Christine D. Esper, Pratibha G. Aia, Leslie J. Cloud and Stewart A. Factor

18 Stiff Person Syndrome 283
Philip D. Thompson and Hans-Michael Meinck

Part IV Chorea, Tics and other Movement Disorders

19 Huntington’s Disease 295
Kevin M. Biglan and Ira Shoulson

20 Chorea 317
Francisco Cardoso

21 Treatment of Tics and Tourette Syndrome 331
Harvey S. Singer and Erika L.F. Hedderick

22 Therapeutics of Paroxysmal Dyskinesias 345
Shyamal H. Mehta and Kapil D. Sethi

23 Treatment of Miscellaneous Disorders 353
Marie Vidailhet, Emmanuel Roze and David Grabli

24 Myoclonus 363
Shu-Ching Hu, Steven J. Frucht and Hiroshi Shibasaki

Part V Drug-induced Movement Disorders

25 Neuroleptic-Induced Movement Disorders 373
S. Elizabeth Zauber and Christopher G. Goetz

26 Other Drug-Induced Dyskinesias 389
Oscar S. Gershanik

Part VI Ataxia and Disorders of Gait and Balance

27 Ataxia 407
Thomas Klockgether

28 Treatment of Gait and Balance Disorders 417
Bastiaan R. Bloem, Alexander C. Geurts, S. Hassin-Baer and Nir Giladi

Part VII Restless Legs Syndrome

29 The Restless Legs Syndrome 447
Richard P. Allen and Birgit H€ogl

Part VIII Pediatric Movement Disorders

30 Pediatric Movement Disorders 471
Jonathan W. Mink

Part IX Psychogenic Movement Disorders

31 Psychogenic Movement Disorders 479
Elizabeth Peckham and Mark Hallett

Index 489

Therapeutics of Parkinsons Disease and Other

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    A Hardback by Mark Hallett, Werner Poewe

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      Publisher: John Wiley & Sons Inc
      Publication Date: Publication Date: 17/10/2008
      ISBN13: 9780470066485, 978-0470066485
      ISBN10: 0470066482

      Description

      Book Synopsis
      • Provides a comprehensive update on therapies for Parkinson's disease and other movement disorders
      • Describes the basic mechanisms of neurodegeneration, pharmacologic interventions for motor and non-motor symptoms, and surgical management
      • Features summary tables and algorithms that serve as a quick reference guide for practical treatment decisions
      • The expert guidance of recognised authorities will enable readers of this book to plan their patients' care with greater confidence


      Trade Review
      "This book can be strongly recommended and is an asset to libraries of both movement disorder specialists and general neurologists. Its logical structure, linking therapy with underlying pathophysiology, means that it will remain a useful reference even as new therapies inevitably emerge." (The Lancet Neurology, July 2009)

      Table of Contents

      Preface ix

      Contributors xi

      Part I Parkinson’s Disease and Parkinsonism

      1 The Etiopathogenesis of Parkinson’s Disease: Basic Mechanisms of Neurodegeneration 3
      C. Warren Olanow and Kevin McNaught

      2 Physiology of Parkinson’s Disease 25
      Shlomo Elias, Zvi Israel and Hagai Bergman

      3 Pharmacology of Parkinson’s Disease 37
      Jonathan M. Brotchie

      4 The Treatment of Early Parkinson’s Disease 49
      Olivier Rascol and Regina Katzenschlager

      5 Treatment of Motor Complications in Advanced Parkinson’s Disease 71
      Susan H. Fox and Anthony E. Lang

      6 Managing the Non-Motor Symptoms of Parkinson’s Disease 91
      Werner Poewe and Klaus Seppi

      7 Surgery for Parkinson’s Disease 121
      Jens Volkmann

      8 Future Cell- and Gene-Based Therapies for Parkinson’s Disease 145
      Tomas Björklund, Asuka Morizane, Deniz Kirik and Patrik Brundin

      9 Parkinson-Plus Disorders 157
      Martin Köllensperger and Gregor K. Wenning

      Part II Tremor Disorders

      10 Essential Tremor 179
      Rodger J. Elble

      11 Other Tremor Disorders 193
      Günther Deuschl

      Part III Dystonia, Cramps, and Spasms

      12 Pathophysiology of Dystonia 205
      Mark Hallett

      13 General Management Approach to Dystonia 217
      Cynthia L. Comella

      14 Botulinum Toxin for Treatment of Dystonia 227
      Dirk Dressler

      15 Surgical Treatments of Dystonia 241
      Christopher Kenney and Joseph Jankovic

      16 Wilson’s Disease 251
      George J. Brewer

      17 Cramps and Spasms 263
      Christine D. Esper, Pratibha G. Aia, Leslie J. Cloud and Stewart A. Factor

      18 Stiff Person Syndrome 283
      Philip D. Thompson and Hans-Michael Meinck

      Part IV Chorea, Tics and other Movement Disorders

      19 Huntington’s Disease 295
      Kevin M. Biglan and Ira Shoulson

      20 Chorea 317
      Francisco Cardoso

      21 Treatment of Tics and Tourette Syndrome 331
      Harvey S. Singer and Erika L.F. Hedderick

      22 Therapeutics of Paroxysmal Dyskinesias 345
      Shyamal H. Mehta and Kapil D. Sethi

      23 Treatment of Miscellaneous Disorders 353
      Marie Vidailhet, Emmanuel Roze and David Grabli

      24 Myoclonus 363
      Shu-Ching Hu, Steven J. Frucht and Hiroshi Shibasaki

      Part V Drug-induced Movement Disorders

      25 Neuroleptic-Induced Movement Disorders 373
      S. Elizabeth Zauber and Christopher G. Goetz

      26 Other Drug-Induced Dyskinesias 389
      Oscar S. Gershanik

      Part VI Ataxia and Disorders of Gait and Balance

      27 Ataxia 407
      Thomas Klockgether

      28 Treatment of Gait and Balance Disorders 417
      Bastiaan R. Bloem, Alexander C. Geurts, S. Hassin-Baer and Nir Giladi

      Part VII Restless Legs Syndrome

      29 The Restless Legs Syndrome 447
      Richard P. Allen and Birgit H€ogl

      Part VIII Pediatric Movement Disorders

      30 Pediatric Movement Disorders 471
      Jonathan W. Mink

      Part IX Psychogenic Movement Disorders

      31 Psychogenic Movement Disorders 479
      Elizabeth Peckham and Mark Hallett

      Index 489

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