Description
Book SynopsisNitro compounds (compounds containing NO2) are useful intermediates for the synthesis of natural products and other complex organic molecules. Historically used in the synthesis of explosives, they are increasingly important to the modern pharmaceutical, agrochemical, and fine chemical industries.
Trade Review"Special attention is paid to environmentally-friendly methods for nitration, and new reactions discovered in recent years." (SciTech Book News, Vol. 25, No. 3, September 2001)
"This book is a very useful reference work that is highly recommended to synthetic organic chemists who might use nitro compounds in their work." (Polymer News, Vol. 26, No. 9, 2001)
"this book is thoughtfully laid out, well referenced and easy to read. a highly competent rendering of the use of the nitro group in modern organic synthesis." (Perkin Transactions, No.19, 2001)
"...outstanding new addition to the Wiley Series in Organic Nitro Chemistry.... I can recommend this book as an important addition to chemistry libraries and a valuable acquisition by the synthetic organic chemist.... Even if one is not actually working with nitro compounds, there is enough fascinating chemistry in this volume to foment the imagination of any synthetic chemist." (Journal of Natural Products, Vol. 64, 2001)
"In conclusion, this monograph provides the organic chemistry community with a comprehensive, yet clearly presented account of nitro group chemistry." (Synthesis, No. 16, 2001)
"...there is no comparable book available.... It will be of considerable interest to upper-division undergraduates...and especially to graduate students, faculty, and professionals..." (Choice, Vol. 39, No. 5, January 2002)
"...a valuable addition to institutional libraries and to the personal library of scientists.... Highly recommended." (Journal of Medicinal Chemistry, Vol. 45, No. 6, 2002)
"excellent coverage of the use of nitro groups in organic synthesis" (Chemistry & Industry, 15 April 2002)
Table of ContentsSeries Foreword.
Preface.
Acknowledgments.
Abbreviations.
Introduction.
Preparation of Nitro Compounds.
The Nitro-Aldol (Henry) Reaction.
Michael Addition.
Alkylation, Acylation, Halogenation of Nitro Compounds.
Conversion of Nitro Compounds into Other Compounds.
Substitution and Elimination of NO_2 in R-NO_2._
Cycloaddition Chemistry of Nitro Compounds.
Nucleophilic Aromatic Displacement.
Synthesis of Heterocyclic Compounds.
Index.
