Description
Book Synopsis The American Psychiatric Association Publishing Textbook of Psychopharmacology is an indispensable and comprehensive resource for clinicians and trainees who prescribe psychotropic medications. Updated to reflect the new DSM-5 classification, this revised Fifth Edition maintains the user-friendly structure of its predecessors while offering in-depth coverage of the latest research in pharmacological principles, classes of drugs, and psychiatric disorders. Introductory chapters provide a theoretical grounding in clinical applications, with topics ranging from neurotransmitters to brain imaging in psychopharmacology. The bulk of the book is devoted to various classes of drugs, including antidepressants, anxiolytics, antipsychotics, mood stabilizers, and other agents, with each class divided into chapters on specific drugs—either new or revised to include the latest findings and trends. Finally, the section on psychopharmacological treatment addresses evidence-based principles of clinical care for the full spectrum of mental disorders and conditions—from depression to chronic pain—as well as for specific populations and circumstances—from children and adolescents to psychiatric emergencies—offering information on topics such as medication selection, combination and maintenance dosing regimens, monitoring and management of side effects, and strategies for optimizing treatment response.
The book's beneficial features are many:
• The section on principles of pharmacology has been revised and reorganized to incorporate recent discoveries from the fields of neurobiology, genetics, brain imaging, and epidemiology.
• History and discovery, structure–activity relationships, pharmacological profiles, pharmacokinetics and disposition, mechanisms of action, indications and efficacy, side effects and toxicology, and drug–drug interactions are addressed for each agent. This consistent structure places the desired information at the clinician's fingertips and facilitates study for trainees.
• Coverage of drugs approved since the last edition is thorough, encompassing new antidepressants (e.g., vortioxetine), new antipsychotics (e.g., cariprazine), and agents on the clinical horizon (e.g., ketamine).
• More than 180 tables and graphs present critically important data in an accessible way.
A work of uncommon scientific rigor and clinical utility, The American Psychiatric Association Publishing Textbook of Psychopharmacology provides state-of-the-art information on both the principles and the practice of psychopharmacological treatment of psychiatric disorders.
Trade ReviewThis comprehensive, up-to-date reference on present day psychotropics thoroughly reviews the basics of psychopharmacology and individual drugs. The chapters on treatment tend to be a bit thin, although they cover all the evidence-based research. Unfortunately, while these chapters cover the basic "must know" information, they do not help with the management of the many complicated patients we encounter on a daily basis. The useful appendix at the end of the book covers both approved and off-label uses of various medications including dosing.
-- Michael Easton, MD(Rush University Medical Center) * Doody *
Table of ContentsContributors
Introduction
Part I: Principles of Pharmacology
Chapter 1. Basic Principles of Molecular Biology and Genomics
Chapter 2. Neurotransmitters
Chapter 3. Genetics
Chapter 4. Psychoneuroendocrinology
Chapter 5. Brain–Immune System Interactions
Chapter 6. Pharmacokinetics
Chapter 7. Brain Imaging in Psychopharmacology
Part II: Classes of Psychiatric Treatments Antidepressants and Anxiolytics
Chapter 8. Monoamine Oxidase Inhibitors
Chapter 9. Tricyclics
Chapter 10. Fluoxetine
Chapter 11. Sertraline
Chapter 12. Paroxetine
Chapter 13. Fluvoxamine
Chapter 14. Citalopram
Chapter 15. Trazodone and Nefazodone
Chapter 16. Vortioxetine
Chapter 17. Mirtazapine
Chapter 18. Bupropion
Chapter 19. Venlafaxine
Chapter 20. Duloxetine, Milnacipran, and Levomilnacipran
Chapter 21. Ketamine
Chapter 22. Benzodiazepines
Chapter 23. Buspirone
Antipsychotics
Chapter 24. Classic Antipsychotics
Chapter 25. Clozapine
Chapter 26. Olanzapine
Chapter 27. Quetiapine
Chapter 28. Risperidone and Paliperidone
Chapter 29. Aripiprazole
Chapter 30. Ziprasidone
Chapter 31. Asenapine
Chapter 32. Iloperidone
Chapter 33. Lurasidone
Chapter 34. Cariprazine
Chapter 35. Drugs to Treat Extrapyramidal Side Effects
Drugs for Treatment of Bipolar Disorder
Chapter 36. Lithium
Chapter 37. Valproate Bowden
Chapter 38. Carbamazepine
Chapter 39. Gabapentin
Chapter 40. Lamotrigine
Chapter 41. Topiramate
Other Agents
Chapter 42. Agents for Cognitive Disorders
Chapter 43. Sedative-Hypnotics
Chapter 44. Psychostimulants and Wakefulness-Promoting Agents
Chapter 45. Neurostimulation
Part III: Psychopharmacological Treatment
Chapter 46. Treatment of Depression
Chapter 47. Treatment of Bipolar Disorder
Chapter 48. Treatment of Anxiety and Related Disorders
Chapter 49. Treatment of Schizophrenia
Chapter 50. Treatment of Substance-Related Disorders
Chapter 51. Treatment of Personality Disorders
Chapter 52. Treatment of Eating Disorders
Chapter 53. Treatment of Insomnia
Chapter 54. Treatment of Chronic Pain
Chapter 55. Treatment of Child and Adolescent Disorders
Chapter 56. Treatment During Late Life
Chapter 57. Psychopharmacology During Pregnancy and Lactation
Chapter 58. Treatment of Psychiatric Emergencies
Chapter 59. Treatment of Agitation and Aggression in the Elderly
