Description
Book SynopsisThis highly illustrated book provides an up-to-date description of the structure and function of the translation system including ribosomes, tRNAs, translation factors, antibiotics and aminoacyl-tRNA synthetases.Research on translation is undergoing rapid changes and is receiving significant attention as evidenced by the Nobel Prize in Chemistry 2009. The structural research by crystallography and cryo-EM forms part of an interactive framework that involves biochemistry and molecular computation. The book provides a comprehensive overview of translation in light of the structural results. It is a valuable resource for scientists in this and related fields, as well as for students taking courses with a focus on translation.There is no other book in this field currently except the previous edition of this book. The authors have for a long time worked in the field of structure and function of the translation system.
Table of ContentsThe Basics of Translation; Historical Milestones; Methods of Studying Structure; The Message - mRNA; The Adaptor - tRNA; The Workbench - Ribosomes; The Structure of the Ribosome; Ribosomal Sites and Ribosomal States; The Catalysts - Translation Factors; Inhibitors of Protein Synthesis - Antibiotics, Resistance; The Process - Translation; Protein Processing, Folding and Targeting; Evolution of the Translation Apparatus.
