Description

Book Synopsis

Since the first edition of Stochastic Modelling for Systems Biology, there have been many interesting developments in the use of likelihood-free methods of Bayesian inference for complex stochastic models. Having been thoroughly updated to reflect this, this third edition covers everything necessary for a good appreciation of stochastic kinetic modelling of biological networks in the systems biology context. New methods and applications are included in the book, and the use of R for practical illustration of the algorithms has been greatly extended. There is a brand new chapter on spatially extended systems, and the statistical inference chapter has also been extended with new methods, including approximate Bayesian computation (ABC). Stochastic Modelling for Systems Biology, Third Edition is now supplemented by an additional software library, written in Scala, described in a new appendix to the book.

New in the Third Edition

  • New chapter on s

    Trade Review

    "...stochastic modeling has drawn the attention of many researchers in biology and physiology. A textbook, with much elaboration, is highly valuable to understanding the underlying mathematical and computational methods in biological stochastic modeling. Prof Wilkinson has designed the content of this book to fill a gap in the educational text/reference books available for students/researchers learning about stochastic modeling in biological systems... This third edition book almost covers all of the material necessary for students studying stochastic kinetics modelling. The exercises in every chapter certainly illustrate the theory and concept of the book. Appendices A and B elaborate on all of the SBML code and other software associated with the book. The codes are also complemented by links to the author’s webpage and a GitHub repository. The author must be appreciated for adding so many references for further reading. The content of the book is designed for a one-semester graduate-level course in stochastic modeling in biology. Thus, this book is targeted at master and graduate students in interdisciplinary subjects such as applied mathematics, computational biology, bioinformatics, biophysics, Biochemistry, and biomedical engineering."
    - Chitaranjan Mahapatra, Appeared in ISCB News, January 2020



    Table of Contents

    Introduction to biological modelling

    Representation of biochemical networks

    Probability models

    Stochastic simulation

    Markov processes

    Chemical and biochemical kinetics

    Case studies

    Beyond the Gillespie algorithm

    Spatially extended systems

    Bayesian inference and MCMC

    Inference for stochastic kinetic models

    Conclusions

    Appendices

Stochastic Modelling for Systems Biology Third

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    £87.39

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    RRP £91.99 – you save £4.60 (5%)

    Order before 4pm tomorrow for delivery by Fri 26 Jun 2026.

    A Hardback by Darren J. Wilkinson

    15 in stock


      View other formats and editions of Stochastic Modelling for Systems Biology Third by Darren J. Wilkinson

      Publisher: Taylor & Francis Ltd
      Publication Date: 1/21/2018 12:11:00 AM
      ISBN13: 9781138549289, 978-1138549289
      ISBN10: 1138549282

      Description

      Book Synopsis

      Since the first edition of Stochastic Modelling for Systems Biology, there have been many interesting developments in the use of likelihood-free methods of Bayesian inference for complex stochastic models. Having been thoroughly updated to reflect this, this third edition covers everything necessary for a good appreciation of stochastic kinetic modelling of biological networks in the systems biology context. New methods and applications are included in the book, and the use of R for practical illustration of the algorithms has been greatly extended. There is a brand new chapter on spatially extended systems, and the statistical inference chapter has also been extended with new methods, including approximate Bayesian computation (ABC). Stochastic Modelling for Systems Biology, Third Edition is now supplemented by an additional software library, written in Scala, described in a new appendix to the book.

      New in the Third Edition

      • New chapter on s

        Trade Review

        "...stochastic modeling has drawn the attention of many researchers in biology and physiology. A textbook, with much elaboration, is highly valuable to understanding the underlying mathematical and computational methods in biological stochastic modeling. Prof Wilkinson has designed the content of this book to fill a gap in the educational text/reference books available for students/researchers learning about stochastic modeling in biological systems... This third edition book almost covers all of the material necessary for students studying stochastic kinetics modelling. The exercises in every chapter certainly illustrate the theory and concept of the book. Appendices A and B elaborate on all of the SBML code and other software associated with the book. The codes are also complemented by links to the author’s webpage and a GitHub repository. The author must be appreciated for adding so many references for further reading. The content of the book is designed for a one-semester graduate-level course in stochastic modeling in biology. Thus, this book is targeted at master and graduate students in interdisciplinary subjects such as applied mathematics, computational biology, bioinformatics, biophysics, Biochemistry, and biomedical engineering."
        - Chitaranjan Mahapatra, Appeared in ISCB News, January 2020



        Table of Contents

        Introduction to biological modelling

        Representation of biochemical networks

        Probability models

        Stochastic simulation

        Markov processes

        Chemical and biochemical kinetics

        Case studies

        Beyond the Gillespie algorithm

        Spatially extended systems

        Bayesian inference and MCMC

        Inference for stochastic kinetic models

        Conclusions

        Appendices

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